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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Cash flows from operating activities: |  |  |
Net income (loss) | $ 340,660 | $ 948,581 | $ (295,697)
Adjustments to reconcile net income (loss) to net cash provided by operating activities: |  |  |
Depreciation and amortization | 67,855 | 57,844 | 51,807
Stock-based compensation | 188,420 | 183,006 | 177,877
Deferred income taxes (including benefit from valuation allowance release) | 57,091 | (465,604) | (350)
Unrealized foreign exchange losses (gains) and other, net | 17,366 | 1,417 | 546
Unrealized loss (gain) on long term investments | 87,590 | 24,072 | (10,426)
Loss on change in fair value of acquisition-related contingent consideration | 12,149 | 14,741 | 23,385
Changes in operating assets and liabilities: |  |  |
Accounts receivable | (28,579) | (134,306) | (173,185)
Prepaid expenses and other assets | (30,739) | (64,080) | (8,050)
Inventory | (67,504) | (20,965) | (19,468)
Accounts payable | 105,436 | 73,343 | 15,120
Accrued and other liabilities | 220,196 | 131,439 | 113,842
Net cash provided by (used in) operating activities | 969,941 | 749,488 | (124,599)
Cash flows from investing activities: |  |  |
Purchase of long term investments | 0 | (33,510) | (95,468)
Sale of long term investments | 0 | 10,473 | 17,250
Capital expenditures | (77,833) | (181,006) | (187,379)
Purchases of marketable securities | (79,860) | (235,167) | (516,874)
Sale and maturities of marketable securities | 79,151 | 231,511 | 513,470
Net cash used in investing activities | (78,542) | (207,699) | (269,001)
Cash flows from financing activities: |  |  |
Proceeds from issuance of common stock under stock plans | 61,115 | 58,626 | 133,064
Tax withholdings related to restricted and performance share vesting | (26,301) | (29,940) | (22,759)
Payment of finance lease liabilities | (2,862) | (2,417) | (836)
Payment of contingent consideration | (32,746) | (20,093) | (37,760)
Net cash (used in) provided by financing activities | (794) | 6,176 | 71,709
Effect of exchange rates on cash, cash equivalents, and restricted cash | 3,355 | (3,570) | 2,949
Net increase (decrease) in cash, cash equivalents, and restricted cash | 893,960 | 544,395 | (318,942)
Cash, cash equivalents, and restricted cash at beginning of period | 2,059,160 | 1,514,765 | 1,833,707
Cash, cash equivalents, restricted cash and investments at end of period | 2,953,120 | 2,059,160 | 1,514,765
Supplemental Schedule of Cash Flow Information |  |  |
Income taxes paid | 136,242 | 67,731 | 70,712
Reclassification to common stock and additional paid in capital in connection with conversions of 1.25% convertible senior notes due 2020 | 0 | 0 | 18,999
Unpaid purchases of property and equipment | 3,493 | 27,098 | 22,807
Leased assets obtained in exchange for new operating lease liabilities | 6,745 | 14,416 | 19,908
Leased assets obtained in exchange for new finance lease liabilities | $ 1,862 | $ 1,513 | $ 2,160

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