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Revenues (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Revenues |  |  |
Total revenues | $ 3,394,635 | $ 2,986,267 | $ 2,666,702
Product revenues, net |  |  |
Revenues |  |  |
Total revenues | 2,746,897 | 2,322,012 | 2,068,736
JAKAFI |  |  |
Revenues |  |  |
Total revenues | 2,409,225 | 2,134,508 | 1,937,850
ICLUSIG |  |  |
Revenues |  |  |
Total revenues | 105,838 | 109,395 | 105,002
PEMAZYRE |  |  |
Revenues |  |  |
Total revenues | 83,445 | 68,531 | 25,884
MINJUVI |  |  |
Revenues |  |  |
Total revenues | 19,654 | 4,910 | 0
OPZELURA |  |  |
Revenues |  |  |
Total revenues | 128,735 | 4,668 | 0
Product royalty revenues |  |  |
Revenues |  |  |
Total revenues | 482,738 | 569,255 | 392,966
JAKAVI Royalty Revenues |  |  |
Revenues |  |  |
Total revenues | 331,575 | 337,991 | 277,902
OLUMIANT Royalty Revenues |  |  |
Revenues |  |  |
Total revenues | 134,547 | 220,875 | 110,920
TABRECTA Royalty Revenues |  |  |
Revenues |  |  |
Total revenues | 15,411 | 10,389 | 4,144
PEMAZYRE Royalty Revenues |  |  |
Revenues |  |  |
Total revenues | 1,205 | 0 | 0
Milestone and contract revenues |  |  |
Revenues |  |  |
Total revenues | $ 165,000 | $ 95,000 | $ 205,000

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