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Inventory (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Inventory Disclosure [Abstract]    
Raw materials $ 31,874 $ 1,275
Work-in-process 54,455 39,895
Finished goods 34,630 15,768
Total inventory 120,959 56,938
Inventories - current 41,995 27,904
Inventories-noncurrent 78,964 $ 29,034
Inventory incurred prior to FDA approval $ 47,500  
Period of lower average per unit cost of materials 25 months