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License Agreements - Novartis (Details) - Novartis - USD ($) $ in Millions | 1 Months Ended | 3 Months Ended | 161 Months Ended |
--- | --- | --- | --- | ---
Nov. 30, 2009 | Mar. 31, 2023 | Mar. 31, 2022 | Mar. 31, 2023 | Dec. 31, 2022
License Agreements |  |  |  |  |
Royalties payable |  | $ 276.9 |  | $ 276.9 | $ 253.5
JAKAFI | UNITED STATES |  |  |  |  |
License Agreements |  |  |  |  |
Royalties payable on net sales |  | 23.4 | $ 21.7 |  |
JAKAFI | Non-US |  |  |  |  |
License Agreements |  |  |  |  |
Royalties payable on net sales |  | 76.7 | 70.9 |  |
TABRECTA PROD SERV | Non-US |  |  |  |  |
License Agreements |  |  |  |  |
Royalties payable on net sales |  | $ 4.2 | $ 3.5 |  |
Minimum | JAKAVI |  |  |  |  |
License Agreements |  |  |  |  |
Royalty payments on future global net sales (as a percent) |  | 12.00% |  |  |
Maximum | JAKAVI |  |  |  |  |
License Agreements |  |  |  |  |
Royalty payments on future global net sales (as a percent) |  | 14.00% |  |  |
Development Milestones |  |  |  |  |
License Agreements |  |  |  |  |
Amount recognized and received for the achievement of a predefined milestone |  |  |  | 157.0 |
Development Milestones | Maximum |  |  |  |  |
License Agreements |  |  |  |  |
Upfront and immediate milestone payment to be received under license agreement | $ 174.0 |  |  |  |
Regulatory Milestones |  |  |  |  |
License Agreements |  |  |  |  |
Amount recognized and received for the achievement of a predefined milestone |  |  |  | 340.0 |
Regulatory Milestones | Maximum |  |  |  |  |
License Agreements |  |  |  |  |
Upfront and immediate milestone payment to be received under license agreement | 495.0 |  |  |  |
Commercialization Milestones |  |  |  |  |
License Agreements |  |  |  |  |
Amount recognized and received for the achievement of a predefined milestone |  |  |  | $ 200.0 |
Commercialization Milestones | Maximum |  |  |  |  |
License Agreements |  |  |  |  |
Upfront and immediate milestone payment to be received under license agreement | 500.0 |  |  |  |
Development and Regulatory Milestones | Maximum |  |  |  |  |
License Agreements |  |  |  |  |
Upfront and immediate milestone payment to be received under license agreement | $ 75.0 |  |  |  |

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- Definition The increase (decrease) during the reporting period in the obligations due for compensation payments related to the use of copyrights, patents, trade names, licenses, technology. Royalty payments are also paid by the lease holders for oil, gas, and mineral extraction. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=126954810&loc=d3e3602-108585 + Details
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