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Accrued and Other Current Liabilities (Tables) | 3 Months Ended
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Mar. 31, 2023
Payables and Accruals [Abstract] |
Schedule of accrued and other current liabilities | Accrued and other current liabilities consisted of the following (in thousands):
| March 31, 2023 |  | December 31, 2022
Royalties | $ | 286,230 |  | $ | 263,466
Clinical related costs | 117,417 |  | 130,570
Sales allowances | 220,753 |  | 192,133
Sales and marketing | 60,674 |  | 31,149
Construction in progress | 3,059 |  | 3,493
Operating lease liabilities | 7,388 |  | 8,195
Other current liabilities | 129,922 |  | 72,047
Total accrued and other current liabilities | $ | 825,443 |  | $ | 701,053

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