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License Agreements - Syros (Details) $ in Thousands | 1 Months Ended | 3 Months Ended |
--- | --- | --- | ---
Jan. 31, 2018 USD ($) item | Mar. 31, 2023 USD ($) shares | Mar. 31, 2022 USD ($) | Dec. 31, 2022 USD ($)
License Agreements |  |  |  |  |
Fair market long term investments |  | $ 128,313 |  | $ 133,676 | [1]
Unrealized gain (loss) on long term investments |  | $ (5,318) | $ (46,585) |  |
Syros Pharmaceuticals, Inc. |  |  |  |  |
License Agreements |  |  |  |  |
Common stock held from investment (in shares) | shares |  | 93,753 |  |  |
Fair market long term investments |  | $ 300 |  | $ 300 |
Unrealized gain (loss) on long term investments |  | $ (100) | $ (1,900) |  |
Syros Pharmaceuticals, Inc. |  |  |  |  |
License Agreements |  |  |  |  |
Number of program targets | item | 7 |  |  |  |
Syros Pharmaceuticals, Inc. | Maximum |  |  |  |  |
License Agreements |  |  |  |  |
Target selection and option exercise fee payment | $ 54,000 |  |  |  |
Syros Pharmaceuticals, Inc. | Maximum | Development and Regulatory Milestones |  |  |  |  |
License Agreements |  |  |  |  |
Additional milestone payments under the license agreement | 50,000 |  |  |  |
Syros Pharmaceuticals, Inc. | Maximum | Commercialization Milestones |  |  |  |  |
License Agreements |  |  |  |  |
Additional milestone payments under the license agreement | $ 65,000 |  |  |  |
[1] | The condensed consolidated balance sheet at December 31, 2022 has been derived from the audited consolidated financial statements at that date.

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