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Inventory (Details) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
Dec. 31, 2022
Raw materials $ 29,448 $ 31,874
Work-in-process 93,829 54,455
Finished goods 34,287 34,630
Total inventory 157,564 120,959
Inventories - current 40,876 41,995 [1]
Inventories-noncurrent 116,688 $ 78,964 [1]
Inventory incurred prior to FDA approval $ 40,700  
Maximum    
Period of lower average per unit cost of materials 24 months  
[1] The condensed consolidated balance sheet at December 31, 2022 has been derived from the audited consolidated financial statements at that date.