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License Agreements - Agenus (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended
	Feb. 28, 2017	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022
License Agreements
Fair market long term investments		$ 128,313		$ 133,676	[1]
Unrealized gain (loss) on long term investments		$ (5,318)	$ (46,585)
Agenus
License Agreements
Common stock held from investment (in shares)		12,100,000
Fair market long term investments		$ 18,300		$ 29,000
Unrealized gain (loss) on long term investments		(10,600)	$ (9,200)
Agenus
License Agreements
Period of notice for termination of license agreement	12 months
Agenus | Development, Regulatory and Commercialization Milestones
License Agreements
Milestone payment made under license agreement		30,000
Additional milestone payments under the license agreement		$ 500,000
Royalty-bearing product other than GITR, OX40 and one undisclosed target | Minimum | Agenus
License Agreements
Royalty payments on future global net sales (as a percent)	6.00%
Royalty-bearing product other than GITR, OX40 and one undisclosed target | Maximum | Agenus
License Agreements
Royalty payments on future global net sales (as a percent)	12.00%
Royalty-bearing product GITR, OX40 and one undisclosed target | Maximum | Agenus
License Agreements
Royalty payments on future global net sales (as a percent)	15.00%
[1] The condensed consolidated balance sheet at December 31, 2022 has been derived from the audited consolidated financial statements at that date.

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