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License Agreements - MacroGenics (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended
Mar. 31, 2023
Jul. 31, 2022
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
License Agreements          
Research and development     $ 406,641 $ 353,373  
MacroGenics          
License Agreements          
Research and development     17,800 $ 13,500  
MacroGenics | Accrued Liabilities          
License Agreements          
Accrued and other liabilities $ 1,300   $ 1,300   $ 2,900
MacroGenics | Minimum          
License Agreements          
Royalty payments on future global net sales (as a percent)     15.00%    
MacroGenics | Maximum          
License Agreements          
Royalty payments on future global net sales (as a percent)     24.00%    
Regulatory Milestone | MacroGenics          
License Agreements          
Milestone payment made under license agreement 15,000        
Milestone payment, estimated useful life     13 years 6 months    
Development and Regulatory Milestones | MacroGenics | Maximum          
License Agreements          
Additional milestone payments under the license agreement 320,000   $ 320,000    
Development Milestones | MacroGenics          
License Agreements          
Milestone payment made under license agreement   $ 30,000      
Developmental And Regulatory Milestones | MacroGenics          
License Agreements          
Milestone payment made under license agreement     115,000    
Commercialization Milestones | MacroGenics | Maximum          
License Agreements          
Additional milestone payments under the license agreement $ 330,000   $ 330,000