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Property and Equipment, net - Property and equipment, net (Details) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Property and equipment, net
Property and Equipment, gross	$ 967,377	$ 952,124
Less accumulated depreciation and amortization	(225,676)	(212,814)
Property and equipment, net	741,701	739,310	[1]
Office equipment
Property and equipment, net
Property and Equipment, gross	23,144	22,734
Laboratory equipment
Property and equipment, net
Property and Equipment, gross	195,999	192,141
Computer equipment
Property and equipment, net
Property and Equipment, gross	94,661	92,115
Land
Property and equipment, net
Property and Equipment, gross	10,484	10,429
Building and leasehold improvements
Property and equipment, net
Property and Equipment, gross	567,863	564,170
Operating lease right-of-use assets
Property and equipment, net
Property and Equipment, gross	21,818	23,311
Construction in progress
Property and equipment, net
Property and Equipment, gross	$ 53,408	$ 47,224
[1] The condensed consolidated balance sheet at December 31, 2022 has been derived from the audited consolidated financial statements at that date.

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Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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