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License Agreements - Merus (Details) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | ---
Jan. 31, 2023 USD ($) | Jan. 31, 2022 item | Dec. 31, 2016 item | Jun. 30, 2023 USD ($) shares | Jun. 30, 2022 USD ($) | Jun. 30, 2023 USD ($) shares | Jun. 30, 2022 USD ($) | Dec. 31, 2022 USD ($)
License Agreements |  |  |  |  |  |  |  |
Unrealized gain (loss) on long term investments |  |  |  | $ 41,811 | $ (24,897) | $ 36,493 | $ (71,482) |
Merus |  |  |  |  |  |  |  |
License Agreements |  |  |  |  |  |  |  |
Common stock held from investment (in shares) | shares |  |  |  | 3,600,000 |  | 3,600,000 |  |
Fair market value of our long term investments |  |  |  | $ 93,500 |  | $ 93,500 |  | $ 54,900
Unrealized gain (loss) on long term investments |  |  |  | 28,200 | $ (13,500) | 38,600 | $ (32,500) |
Merus |  |  |  |  |  |  |  |
License Agreements |  |  |  |  |  |  |  |
Number of independent programs | item |  |  | 10 |  |  |  |  |
Number of additional preclinical discovery programs | item |  | 10 |  |  |  |  |  |
Number of programs under the resulting products are co-funded for development | item |  | 2 |  |  |  |  |  |
Associated future global development costs , if elected to co-develop (as a percent) |  | 35.00% |  |  |  |  |  |
Milestone payment made under license agreement | $ 2,500 |  |  |  |  | $ 5,500 |  |
Merus | UNITED STATES |  |  |  |  |  |  |  |
License Agreements |  |  |  |  |  |  |  |
Profit sharing (as a percent) |  |  |  |  |  | 50.00% |  |
Percentage of profit (losses) |  |  |  |  |  | 50.00% |  |
Merus | Minimum |  |  |  |  |  |  |  |
License Agreements |  |  |  |  |  |  |  |
Royalty payments on future global net sales (as a percent) |  |  |  |  |  | 6.00% |  |
Merus | Minimum | Non-US |  |  |  |  |  |  |  |
License Agreements |  |  |  |  |  |  |  |
Royalty payments on future global net sales (as a percent) |  |  |  |  |  | 6.00% |  |
Merus | Maximum |  |  |  |  |  |  |  |
License Agreements |  |  |  |  |  |  |  |
Royalty payments on future global net sales (as a percent) |  |  |  |  |  | 10.00% |  |
Merus | Maximum | UNITED STATES |  |  |  |  |  |  |  |
License Agreements |  |  |  |  |  |  |  |
Royalty payments on future global net sales (as a percent) |  |  |  |  |  | 4.00% |  |
Merus | Maximum | Non-US |  |  |  |  |  |  |  |
License Agreements |  |  |  |  |  |  |  |
Royalty payments on future global net sales (as a percent) |  |  |  |  |  | 10.00% |  |
Merus | Development and Regulatory Milestones | Maximum |  |  |  |  |  |  |  |
License Agreements |  |  |  |  |  |  |  |
Additional milestone payments under the license agreement |  |  |  | 100,000 |  | $ 100,000 |  |
Merus | Commercialization Milestones | Maximum |  |  |  |  |  |  |  |
License Agreements |  |  |  |  |  |  |  |
Additional milestone payments under the license agreement |  |  |  | $ 250,000 |  | $ 250,000 |  |

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