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License Agreements - Lilly (Details) - USD ($) $ in Thousands	1 Months Ended			3 Months Ended		6 Months Ended		163 Months Ended
	Mar. 31, 2022	May 31, 2019	Dec. 31, 2009	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Mar. 31, 2016
License Agreements
Total revenues				$ 954,610	$ 911,397	$ 1,763,283	$ 1,644,632
OLUMIANT Royalty Revenues
License Agreements
Total revenues				32,009	30,254	66,164	78,318
Eli Lilly | OLUMIANT
License Agreements
Total revenues				0	70,000	0	70,000
Eli Lilly | OLUMIANT Royalty Revenues | Non-US
License Agreements
Royalties payable on net sales				$ 32,000	$ 30,300	$ 66,200	$ 78,300
Development Milestones | Eli Lilly
License Agreements
Amount recognized and received for the achievement of a predefined milestone								$ 149,000
Development Milestones | Maximum | Eli Lilly
License Agreements
Upfront and immediate milestone payment to be received under license agreement			$ 150,000
Regulatory Milestones | Eli Lilly
License Agreements
Amount recognized and received for the achievement of a predefined milestone								335,000
Regulatory Milestones | Eli Lilly | GVHD
License Agreements
Milestone payment made under license agreement		$ 20,000
Regulatory Milestones | Eli Lilly | GVHD | Europe
License Agreements
Milestone payment made under license agreement	$ 20,000
Regulatory Milestones | Maximum | Eli Lilly
License Agreements
Upfront and immediate milestone payment to be received under license agreement			365,000
Regulatory Milestones | Maximum | Eli Lilly | GVHD
License Agreements
Additional milestone payments under the license agreement									$ 40,000
Commercialization Milestones | Eli Lilly
License Agreements
Amount recognized and received for the achievement of a predefined milestone								$ 50,000
Commercialization Milestones | Maximum | Eli Lilly
License Agreements
Upfront and immediate milestone payment to be received under license agreement			$ 150,000

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