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License Agreements - Merus (Details)
$ in Thousands
 1 Months Ended 3 Months Ended 6 Months Ended
Jan. 31, 2023
USD ($)
Jan. 31, 2022
item
Dec. 31, 2016
item
Jun. 30, 2023
USD ($)
shares
Jun. 30, 2022
USD ($)
Jun. 30, 2023
USD ($)
shares
Jun. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
License Agreements                
Unrealized gain (loss) on long term investments       $ 41,811 $ (24,897) $ 36,493 $ (71,482)  
Merus                
License Agreements                
Common stock held from investment (in shares) | shares       3,600,000   3,600,000    
Fair market value of our long term investments       $ 93,500   $ 93,500   $ 54,900
Unrealized gain (loss) on long term investments       28,200 $ (13,500) 38,600 $ (32,500)  
Merus                
License Agreements                
Number of independent programs | item     10          
Number of additional preclinical discovery programs | item   10            
Number of programs under the resulting products are co-funded for development | item   2            
Associated future global development costs , if elected to co-develop (as a percent)   35.00%            
Milestone payment made under license agreement $ 2,500         $ 5,500    
Merus | UNITED STATES                
License Agreements                
Profit sharing (as a percent)           50.00%    
Percentage of profit (losses)           50.00%    
Merus | Minimum                
License Agreements                
Royalty payments on future global net sales (as a percent)           6.00%    
Merus | Minimum | Non-US                
License Agreements                
Royalty payments on future global net sales (as a percent)           6.00%    
Merus | Maximum                
License Agreements                
Royalty payments on future global net sales (as a percent)           10.00%    
Merus | Maximum | UNITED STATES                
License Agreements                
Royalty payments on future global net sales (as a percent)           4.00%    
Merus | Maximum | Non-US                
License Agreements                
Royalty payments on future global net sales (as a percent)           10.00%    
Merus | Development and Regulatory Milestones | Maximum                
License Agreements                
Additional milestone payments under the license agreement       100,000   $ 100,000    
Merus | Commercialization Milestones | Maximum                
License Agreements                
Additional milestone payments under the license agreement       $ 250,000   $ 250,000