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License Agreements - MacroGenics (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Mar. 31, 2023
Jul. 31, 2022
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Dec. 31, 2022
License Agreements              
Research and development     $ 375,709 $ 384,007 $ 1,183,100 $ 1,084,576  
MacroGenics              
License Agreements              
Research and development     12,900 $ 41,600 42,800 $ 69,900  
MacroGenics | Accrued Liabilities              
License Agreements              
Accrued and other liabilities     800   $ 800   $ 2,900
MacroGenics | Minimum              
License Agreements              
Royalty payments on future global net sales (as a percent)         15.00%    
MacroGenics | Maximum              
License Agreements              
Royalty payments on future global net sales (as a percent)         24.00%    
Regulatory Milestone | MacroGenics              
License Agreements              
Milestone payment made under license agreement $ 15,000            
Milestone payment, estimated useful life         13 years 6 months    
Development and Regulatory Milestones | MacroGenics | Maximum              
License Agreements              
Additional milestone payments under the license agreement     320,000   $ 320,000    
Development Milestones | MacroGenics              
License Agreements              
Milestone payment made under license agreement   $ 30,000          
Developmental And Regulatory Milestones | MacroGenics              
License Agreements              
Milestone payment made under license agreement         115,000    
Commercialization Milestones | MacroGenics | Maximum              
License Agreements              
Additional milestone payments under the license agreement     $ 330,000   $ 330,000