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Income Taxes - Reconciliation of income taxes (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Reconciliation of income taxes at the U.S. federal statutory rate to the provision for income taxes |  |  |
Provision at U.S. federal statutory rate | $ 175,185 | $ 111,114 | $ 119,793
State and local income taxes | 21,145 | 26,767 | 34,461
Foreign tax rate differential | (96,434) | 13,670 | 55,171
Income tax credits | (1,433,507) | (30,505) | (55,139)
Change in valuation allowance | 1,572,951 | 67,056 | (523,279)
Foreign-derived intangible income | (32,891) | (36,748) | (28,259)
Stock based compensation | 20,971 | 19,704 | 15,497
Acquisitions accounted for as research and development expenses | 4,200 | 14,700 | 0
Other | 4,996 | 2,698 | 3,618
Total provision (benefit) for income taxes | 236,616 | 188,456 | $ (378,137)
Deferred tax assets: |  |  |
Net operating loss carry forwards | 326,446 | 182,193 |
Income tax credits | 1,441,981 | 17,141 |
Capitalized research and development | 457,603 | 265,140 |
Deferred revenue and accruals | 130,291 | 72,657 |
Non-cash compensation | 96,469 | 83,138 |
Acquisition-related contingent consideration | 30,298 | 30,483 |
Intangibles, net | 233,311 | 257,614 |
Long term investments | 42,975 | 54,662 |
Other | 9,044 | 9,600 |
Total gross deferred tax assets | 2,768,418 | 972,628 |
Less valuation allowance for deferred tax assets | (2,096,318) | (472,125) |
Net deferred tax assets | 672,100 | 500,503 |
Deferred tax liabilities: |  |  |
Property and equipment | (34,757) | (33,683) |
Other | (5,457) | (8,879) |
Total gross deferred tax liabilities | (40,214) | (42,562) |
Net deferred tax assets | $ 631,886 | $ 457,941 |

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