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License Agreements - Agenus (Details) - USD ($) $ in Thousands | 1 Months Ended | 12 Months Ended | 108 Months Ended
--- | --- | --- | ---
Feb. 28, 2017 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2023
License agreements |  |  |  |  |
Long term investments |  | $ 187,716 | $ 133,676 |  | $ 187,716
Unrealized gain (loss) on long term investments |  | $ 43,893 | (87,590) | $ (24,072) |
Agenus |  |  |  |  |
License agreements |  |  |  |  |
Investment owned (in shares) |  | 12,100,000 |  |  | 12,100,000
Long term investments |  | $ 10,000 | 29,000 |  | $ 10,000
Unrealized gain (loss) on long term investments |  | (18,900) | $ (9,900) | $ 4,600 |
Agenus |  |  |  |  |
License agreements |  |  |  |  |
Royalty payments on future global net sales | 15.00% |  |  |  |
License agreement, termination period | 12 months |  |  |  |
Milestone payment made under license agreement |  |  |  |  | 30,000
Agenus | Development, Regulatory and Commercialization Milestones |  |  |  |  |
License agreements |  |  |  |  |
Additional milestone payments under the license agreement |  | $ 500,000 |  |  | $ 500,000
Agenus | Development, Regulatory and Commercialization Milestones | Minimum |  |  |  |  |
License agreements |  |  |  |  |
Royalty payments on future global net sales | 6.00% |  |  |  |
Agenus | Development, Regulatory and Commercialization Milestones | Maximum |  |  |  |  |
License agreements |  |  |  |  |
Royalty payments on future global net sales | 12.00% |  |  |  |

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