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Amount of unrealized gain (loss) on investment in equity security measured at fair value with change in fair value recognized in net income (FV-NI).

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Number of shares of investment owned.

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The total amount of investments that are intended to be held for an extended period of time (longer than one operating cycle).

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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License Agreements - Syros (Details) $ in Thousands	1 Months Ended	12 Months Ended
License Agreements - Syros (Details) $ in Thousands	Jan. 31, 2018 programTarget	Dec. 31, 2023 USD ($) shares	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)
License agreements
Long term investments		$ 187,716	$ 133,676
Unrealized gain (loss) on long term investments		43,893	(87,590)	$ (24,072)
Syros Pharmaceuticals, Inc.
License agreements
Number of program targets \| programTarget	7
Long term investments		700	300
Unrealized gain (loss) on long term investments		$ 400	$ (2,700)	$ (7,100)
Stock purchase agreement \| Syros Pharmaceuticals, Inc.
License agreements
Investment owned (in shares) \| shares		100,000