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License Agreements - Novartis (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended		173 Months Ended
	Nov. 30, 2009	Mar. 31, 2024	Mar. 31, 2023	Mar. 31, 2024	Dec. 31, 2023
License Agreements
Total revenues		$ 880,889	$ 808,673
JAKAFI
License Agreements
Total revenues		571,839	579,969
Novartis | JAKAFI | UNITED STATES
License Agreements
Total revenues		23,000	23,400
Royalties payable		398,600		$ 398,600	$ 375,600
Novartis | JAKAVI
License Agreements
Total revenues		89,600	76,700
Novartis | TABRECTA
License Agreements
Total revenues		$ 5,200	$ 4,200
Maximum | Novartis | JAKAVI
License Agreements
Royalty payments on future global net sales (as a percent)		14.00%
Minimum | Novartis | JAKAVI
License Agreements
Royalty payments on future global net sales (as a percent)		12.00%
Development Milestones | Novartis
License Agreements
Amount recognized and received for the achievement of a predefined milestone				157,000
Development Milestones | Maximum | Novartis
License Agreements
Upfront and immediate milestone payment to be received under license agreement	$ 174,000
Regulatory Milestones | Novartis
License Agreements
Amount recognized and received for the achievement of a predefined milestone				345,000
Regulatory Milestones | Maximum | Novartis
License Agreements
Upfront and immediate milestone payment to be received under license agreement	495,000
Commercialization Milestones | Novartis
License Agreements
Amount recognized and received for the achievement of a predefined milestone				$ 200,000
Commercialization Milestones | Maximum | Novartis
License Agreements
Upfront and immediate milestone payment to be received under license agreement	500,000
Development and Regulatory Milestones | Maximum | Novartis | GVHD
License Agreements
Upfront and immediate milestone payment to be received under license agreement	$ 75,000

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