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License Agreements - Syndax (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended		31 Months Ended
	Sep. 30, 2021	Mar. 31, 2024	Mar. 31, 2023	Mar. 31, 2024	Dec. 31, 2023
License Agreements
Long term investments		$ 287,663		$ 287,663	$ 187,716	[1]
Unrealized gain (loss) on long term investments		99,947	$ (5,318)
Research and development		$ 429,260	406,641
Investment in Syndax
License Agreements
Common stock held from investment (in shares)		1,400,000		1,400,000
Long term investments		$ 33,800		$ 33,800	30,700
Unrealized gain (loss) on long term investments		3,100	$ (6,200)
Syndax
License Agreements
Upfront payment under license agreement				117,000
Research and development		7,100
Syndax | UNITED STATES | Syndax
License Agreements
Funding of future development costs (as a percent)	45.00%
Syndax | Accrued Liabilities
License Agreements
Accrued and other liabilities		$ 1,900		1,900	$ 1,800
Syndax | Incyte
License Agreements
Funding of future development costs (as a percent)		55.00%
Syndax | Incyte | UNITED STATES
License Agreements
Funding of future development costs (as a percent)	55.00%
Syndax | Development and Regulatory Milestones | Maximum
License Agreements
Additional milestone payments under the license agreement		$ 220,000		220,000
Syndax | Commercialization Milestones | Maximum
License Agreements
Additional milestone payments under the license agreement		$ 230,000		$ 230,000
[1] The condensed consolidated balance sheet at December 31, 2023 has been derived from the audited consolidated financial statements at that date.

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