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License Agreements - Syndax (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended		6 Months Ended		34 Months Ended
	Sep. 30, 2021	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Dec. 31, 2023
License Agreements
Long term equity investments		$ 29,668		$ 29,668		$ 29,668	$ 187,716	[1]
Research and development		$ 1,138,380	$ 400,750	$ 1,567,640	$ 807,391
Investment in Syndax
License Agreements
Common stock held from investment (in shares)		1,400,000		1,400,000		1,400,000
Long term equity investments		$ 29,200		$ 29,200		$ 29,200	30,700
Unrealized gain (loss) on long term investments		(4,600)	(200)	(1,500)	(6,400)
Syndax
License Agreements
Upfront payment under license agreement						117,000
Research and development		4,700	$ 6,200	11,800	$ 11,800
Accrued and other liabilities		$ 2,600		$ 2,600		2,600	$ 1,800
Syndax | UNITED STATES | Syndax
License Agreements
Funding of future development costs (as a percent)	45.00%
Syndax | Incyte
License Agreements
Funding of future development costs (as a percent)		55.00%	55.00%	55.00%	55.00%
Syndax | Incyte | UNITED STATES
License Agreements
Funding of future development costs (as a percent)	55.00%
Syndax | Development and Regulatory Milestones | Maximum
License Agreements
Additional milestone payments under the license agreement		$ 220,000		$ 220,000		220,000
Syndax | Commercialization Milestones | Maximum
License Agreements
Additional milestone payments under the license agreement		$ 230,000		$ 230,000		$ 230,000
[1] The condensed consolidated balance sheet at December 31, 2023 has been derived from the audited consolidated financial statements at that date.

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