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License Agreements - Agenus (Details) - Agenus - USD ($) $ in Millions | 1 Months Ended | 12 Months Ended | 120 Months Ended
--- | --- | --- | ---
Feb. 28, 2017 | Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2024
License agreements |  |  |  |  |
Royalty payments on future global net sales (as percent) | 15.00% |  |  |  |
License agreement, termination period (in months) | 12 months |  |  |  |
Milestone payment made under license agreement |  |  |  |  | $ 30.0
Shares divested (in shares) |  | 600,000 |  |  |
Proceeds from sale of equity securities, FV-NI |  | $ 1.9 |  |  |
Investment owned (in shares) |  | 0 |  |  | 0
Equity securities, FV-NI |  |  | $ 10.0 |  |
Realized and unrealized loss on equity investments |  | $ 8.2 | $ 18.9 | $ 9.9 |
Development, Regulatory and Commercialization Milestones |  |  |  |  |
License agreements |  |  |  |  |
Additional milestone payments under the license agreement |  | $ 500.0 |  |  | $ 500.0
Development, Regulatory and Commercialization Milestones | Minimum |  |  |  |  |
License agreements |  |  |  |  |
Royalty payments on future global net sales (as percent) | 6.00% |  |  |  |
Development, Regulatory and Commercialization Milestones | Maximum |  |  |  |  |
License agreements |  |  |  |  |
Royalty payments on future global net sales (as percent) | 12.00% |  |  |  |

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