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v3.25.0.1

Segment Reporting - Schedule of Consolidated Net Income (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Revenues from External Customers and Long-Lived Assets [Line Items] |  |  |
Total revenues | $ 4,241,217 | $ 3,695,649 | $ 3,394,635
Costs, expenses and other: |  |  |
Cost of product revenues (including definite-lived intangible amortization) | 312,068 | 254,990 | 206,997
Loss on change in fair value of acquisition-related contingent consideration | 19,803 | 29,202 | 12,149
(Profit) and loss sharing under collaboration agreements | (1,025) | 2,045 | 7,973
Net income | 32,615 | 597,599 | 340,660
Reportable Segment |  |  |
Revenues from External Customers and Long-Lived Assets [Line Items] |  |  |
Total revenues | 4,241,217 | 3,695,649 | 3,394,635
Costs, expenses and other: |  |  |
Cost of product revenues (including definite-lived intangible amortization) | 312,068 | 254,990 | 206,997
Research and development - internal | 957,043 | 815,025 | 739,785
Research and development - external | 866,005 | 775,919 | 720,201
Other research and development | 783,800 | 36,650 | 125,950
Sales and marketing | 945,428 | 876,703 | 770,141
General and administrative | 296,729 | 284,590 | 231,999
Loss on change in fair value of acquisition-related contingent consideration | 19,803 | 29,202 | 12,149
(Profit) and loss sharing under collaboration agreements | (1,025) | 2,045 | 7,973
Other segment items | 28,751 | 22,926 | 238,780
Net income | 32,615 | 597,599 | 340,660
Product revenues, net |  |  |
Revenues from External Customers and Long-Lived Assets [Line Items] |  |  |
Total revenues | 3,618,888 | 3,165,168 | 2,746,897
Product revenues, net | Reportable Segment |  |  |
Revenues from External Customers and Long-Lived Assets [Line Items] |  |  |
Total revenues | 3,618,888 | 3,165,168 | 2,746,897
Product royalty revenues |  |  |
Revenues from External Customers and Long-Lived Assets [Line Items] |  |  |
Total revenues | 579,329 | 523,481 | 482,738
Product royalty revenues | Reportable Segment |  |  |
Revenues from External Customers and Long-Lived Assets [Line Items] |  |  |
Total revenues | 579,329 | 523,481 | 482,738
Milestone and contract revenues |  |  |
Revenues from External Customers and Long-Lived Assets [Line Items] |  |  |
Total revenues | 43,000 | 7,000 | 165,000
Milestone and contract revenues | Reportable Segment |  |  |
Revenues from External Customers and Long-Lived Assets [Line Items] |  |  |
Total revenues | $ 43,000 | $ 7,000 | $ 165,000

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