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License Agreements - Merus (Details) $ in Millions | 1 Months Ended | 12 Months Ended | 97 Months Ended
--- | --- | --- | ---
Dec. 31, 2016 USD ($) program | Dec. 31, 2024 USD ($) shares | Dec. 31, 2023 USD ($) | Dec. 31, 2022 USD ($) | Dec. 31, 2024 USD ($) shares
Merus |  |  |  |  |
License agreements |  |  |  |  |
Shares divested (in shares) | shares |  | 4,000,000.0 |  |  |
Proceeds from sale of equity securities, FV-NI |  | $ 216.1 |  |  |
Investment owned (in shares) | shares |  | 0 |  |  | 0
Equity securities, FV-NI |  |  | $ 110.1 |  |
Realized and unrealized gain (loss) on equity investments |  | $ 106.1 | $ 45.2 | $ (58.0) |
Merus |  |  |  |  |
License agreements |  |  |  |  |
Number of independent programs | program | 10 |  |  |  |
Number of programs under the resulting products are co-funded for development | program | 2 |  |  |  |
Associated future global development costs from the initiation of a Phase IIb trial, if elected to co-develop | 35.00% |  |  |  |
Milestone payment made under license agreement |  |  |  |  | $ 10.0
Merus | United States |  |  |  |  |
License agreements |  |  |  |  |
Profit sharing | 50.00% |  |  |  |
Percentage of profit (losses) | 50.00% |  |  |  |
Merus | Minimum |  |  |  |  |
License agreements |  |  |  |  |
Royalty payments on future global net sales (as percent) | 6.00% |  |  |  |
Merus | Minimum | United States |  |  |  |  |
License agreements |  |  |  |  |
Royalty payments on future global net sales (as percent) | 6.00% |  |  |  |
Merus | Maximum |  |  |  |  |
License agreements |  |  |  |  |
Royalty payments on future global net sales (as percent) | 10.00% |  |  |  |
Percentage of reverse royalty | 4.00% |  |  |  |
Merus | Maximum | United States |  |  |  |  |
License agreements |  |  |  |  |
Royalty payments on future global net sales (as percent) | 10.00% |  |  |  |
Percentage of additional royalties | 4.00% |  |  |  |
Merus | Development and Regulatory Milestones | Maximum |  |  |  |  |
License agreements |  |  |  |  |
Additional milestone payments under the license agreement | $ 100.0 |  |  |  |
Merus | Commercialization Milestones | Maximum |  |  |  |  |
License agreements |  |  |  |  |
Additional milestone payments under the license agreement | $ 250.0 |  |  |  |

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- Definition Represents the percentage of associated future global development costs from the initiation of a Phase IIb trial provided the entity elects to co-develop any compounds and/or indications. + References No definition available. + Details
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