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Revenues (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Revenues
Total revenues	$ 4,241,217	$ 3,695,649	$ 3,394,635
Product revenues, net
Revenues
Total revenues	3,618,888	3,165,168	2,746,897
JAKAFI
Revenues
Total revenues	2,792,107	2,593,732	2,409,225
OPZELURA
Revenues
Total revenues	508,293	337,864	128,735
ICLUSIG
Revenues
Total revenues	114,319	111,623	105,838
MINJUVI/MONJUVI
Revenues
Total revenues	119,236	37,057	19,654
PEMAZYRE
Revenues
Total revenues	81,748	83,642	83,445
ZYNYZ
Revenues
Total revenues	3,185	1,250	0
Product royalty revenues
Revenues
Total revenues	579,329	523,481	482,738
JAKAVI Royalty Revenues
Revenues
Total revenues	418,840	367,583	331,575
OLUMIANT Royalty Revenues
Revenues
Total revenues	135,572	136,138	134,547
TABRECTA Royalty Revenues
Revenues
Total revenues	22,746	17,793	15,411
PEMAZYRE Royalty Revenues
Revenues
Total revenues	2,171	1,967	1,205
Milestone and contract revenues
Revenues
Total revenues	$ 43,000	$ 7,000	$ 165,000

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