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License Agreements - Lilly (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended		184 Months Ended
	Dec. 31, 2009	Mar. 31, 2025	Mar. 31, 2024	Mar. 31, 2025
License Agreements
Total revenues		$ 1,052,898	$ 880,889
Eli Lilly | OLUMIANT
License Agreements
Total revenues		$ 30,800	$ 30,600
Development Milestones | Eli Lilly
License Agreements
Amount recognized and received for the achievement of a predefined milestone				$ 149,000
Development Milestones | Maximum | Eli Lilly
License Agreements
Upfront and immediate milestone payment to be received under license agreement	$ 150,000
Regulatory Milestones | Eli Lilly
License Agreements
Amount recognized and received for the achievement of a predefined milestone				335,000
Regulatory Milestones | Maximum | Eli Lilly
License Agreements
Upfront and immediate milestone payment to be received under license agreement	365,000
Commercialization Milestones | Eli Lilly
License Agreements
Amount recognized and received for the achievement of a predefined milestone				$ 50,000
Commercialization Milestones | Maximum | Eli Lilly
License Agreements
Upfront and immediate milestone payment to be received under license agreement	$ 150,000

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