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Segment Reporting - Schedule of Consolidated Net Income (Details) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total revenues $ 1,052,898 $ 880,889
Costs, expenses and other:    
Cost of product revenues (including definite-lived intangible amortization) 73,188 60,956
Loss (gain) on change in fair value of acquisition-related contingent consideration 11,572 (456)
(Profit) and loss sharing under collaboration agreements 0 (1,025)
Net income 158,203 169,548
Reportable Segment    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total revenues 1,052,898 880,889
Costs, expenses and other:    
Cost of product revenues (including definite-lived intangible amortization) 73,188 60,956
Research and development - internal 228,345 223,096
Research and development - external 193,434 205,164
Other research and development 15,500 1,000
Sales and marketing 257,652 216,813
General and administrative 68,039 83,443
Loss (gain) on change in fair value of acquisition-related contingent consideration 11,572 (456)
(Profit) and loss sharing under collaboration agreements 0 (1,025)
Other segment items 46,965 (77,650)
Net income 158,203 169,548
Product revenues, net    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total revenues 922,274 729,923
Product revenues, net | Reportable Segment    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total revenues 922,274 729,923
Product royalty revenues    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total revenues 130,624 125,966
Product royalty revenues | Reportable Segment    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total revenues 130,624 125,966
Milestone and contract revenues    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total revenues 0 25,000
Milestone and contract revenues | Reportable Segment    
Revenues from External Customers and Long-Lived Assets [Line Items]    
Total revenues $ 0 $ 25,000