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Stock Compensation - Narrative (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Stock compensation        
Stock compensation expense $ 64.6 $ 56.6 $ 125.6 $ 116.4
Dividend yield (as percent)     0.00%  
Assumed annualized forfeiture rate (as a percent)     5.00%  
Share-based Payment Arrangement, Option        
Stock compensation        
Stock option grant term (in years)     10 years  
Vesting period (in years)     4 years  
Percentage of units vesting at the end of each calendar year (as a percent)     25.00%  
Unrecognized compensation cost for nonvested option (in dollars) 20.4   $ 20.4  
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years)     1 year 1 month 6 days  
Share-based Payment Arrangement, Option | Share-based Payment Arrangement, Tranche One        
Stock compensation        
Vesting period (in years)     1 year  
Share-based Payment Arrangement, Option | Share-based Payment Arrangement, Tranche Two        
Stock compensation        
Vesting period (in years)     36 months  
Restricted Stock Units (RSUs)        
Stock compensation        
Vesting period (in years)     4 years  
Percentage of units vesting at the end of each calendar year (as a percent)     25.00%  
Number of shares awarded for each RSU (in shares)     1  
Unrecognized compensation cost for nonvested option (in dollars) 171.8   $ 171.8  
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years)     1 year 2 months 12 days  
Performance Shares        
Stock compensation        
Stock compensation expense 6.9 3.5 $ 10.0 6.9
Unrecognized compensation cost for nonvested option (in dollars) 12.1   $ 12.1  
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years)     1 year 1 month 6 days  
Performance Shares | Minimum        
Stock compensation        
Vesting period (in years)     3 years  
Performance Shares | Maximum        
Stock compensation        
Vesting period (in years)     4 years  
Escient        
Stock compensation        
Asset acquisition, compensation expense   31.5   31.5
Research and Development Expense        
Stock compensation        
Stock compensation expense 37.7 34.5 $ 74.4 71.3
Selling, General and Administrative Expenses        
Stock compensation        
Stock compensation expense 26.1 21.7 49.5 44.1
Cost of Sales        
Stock compensation        
Stock compensation expense $ 0.8 $ 0.4 $ 1.7 $ 1.0