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v3.25.3

Commitments and Contingencies (Details) | 1 Months Ended | 3 Months Ended |
--- | --- | --- | ---
Aug. 31, 2021 USD ($) | Sep. 30, 2025 USD ($) | Dec. 31, 2024 USD ($)
JAKAFI | U.S. Centers for Medicare and Medicaid Services |  |  |
Loss Contingencies [Line Items] |  |  |
Loss contingences, gross to net deduction (as percent) |  | 6.80% |
JAKAFI | Accrued and Other Current Liabilities | U.S. Centers for Medicare and Medicaid Services |  |  |
Loss Contingencies [Line Items] |  |  |
Loss contingency accrual |  | $ 188,900,000 |
Revolving Credit Facility |  |  |
Loss Contingencies [Line Items] |  |  |
Aggregate principal amount | $ 500,000,000.0 |  |
Increase in maximum revolving commitments | $ 250,000,000.0 |  |
Consolidated leverage ratio | 0.25 |  |
Long-term line of credit |  | $ 0 | $ 0
Revolving Credit Facility | Minimum |  |  |
Loss Contingencies [Line Items] |  |  |
Commitment fee | 0.15% |  |
Revolving Credit Facility | Maximum |  |  |
Loss Contingencies [Line Items] |  |  |
Commitment fee | 0.225% |  |
Revolving Credit Facility | Base Rate |  |  |
Loss Contingencies [Line Items] |  |  |
Debt instrument, variable rate floor (as percent) | 1.00% |  |
Revolving Credit Facility | Base Rate | Minimum |  |  |
Loss Contingencies [Line Items] |  |  |
Interest rate margin (as percent) | 0.125% |  |
Revolving Credit Facility | Base Rate | Maximum |  |  |
Loss Contingencies [Line Items] |  |  |
Interest rate margin (as percent) | 0.875% |  |
Revolving Credit Facility | Secured Overnight Financing Rate (SOFR) |  |  |
Loss Contingencies [Line Items] |  |  |
Debt instrument, variable rate floor (as percent) | 0.00% |  |
Debt instrument, credit spread adjustment on variable rate (as percent) | 0.10% |  |
Revolving Credit Facility | Secured Overnight Financing Rate (SOFR) | Minimum |  |  |
Loss Contingencies [Line Items] |  |  |
Interest rate margin (as percent) | 1.125% |  |
Revolving Credit Facility | Secured Overnight Financing Rate (SOFR) | Maximum |  |  |
Loss Contingencies [Line Items] |  |  |
Interest rate margin (as percent) | 1.875% |  |

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- Definition The carrying value as of the balance sheet date of the current and noncurrent portions of long-term obligations drawn from a line of credit, which is a bank's commitment to make loans up to a specific amount. Examples of items that might be included in the application of this element may consist of letters of credit, standby letters of credit, and revolving credit arrangements, under which borrowings can be made up to a maximum amount as of any point in time conditional on satisfaction of specified terms before, as of and after the date of drawdowns on the line. Includes short-term obligations that would normally be classified as current liabilities but for which (a) postbalance sheet date issuance of a long term obligation to refinance the short term obligation on a long term basis, or (b) the enterprise has entered into a financing agreement that clearly permits the enterprise to refinance the short-term obligation on a long term basis and the following conditions are met (1) the agreement does not expire within 1 year and is not cancelable by the lender except for violation of an objectively determinable provision, (2) no violation exists at the BS date, and (3) the lender has entered into the financing agreement is expected to be financially capable of honoring the agreement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(22)) -SubTopic 10 -Topic 210 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 942 -SubTopic 210 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.9-03(16)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147478546/942-210-S99-1 Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 944 -SubTopic 210 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-03(a)(16)(a)(2)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147478777/944-210-S99-1 + Details
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