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Stock Compensation - Narrative (Details) - USD ($) $ in Millions | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 | Sep. 30, 2024 | Jun. 30, 2024 | Sep. 30, 2025 | Sep. 30, 2024
Stock compensation |  |  |  |  |
Stock compensation expense | $ 61.6 | $ 77.9 |  | $ 187.2 | $ 194.3
Dividend yield (as percent) |  |  |  | 0.00% |
Share-based Payment Arrangement, Option |  |  |  |  |
Stock compensation |  |  |  |  |
Stock option grant term (in years) |  |  |  | 10 years |
Vesting period (in years) |  |  |  | 4 years |
Percentage of units vesting at the end of each calendar year (as a percent) |  |  |  | 25.00% |
Unrecognized compensation cost for nonvested option (in USD per share) | 25.6 |  |  | $ 25.6 |
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years) |  |  |  | 1 year 4 months 24 days |
Share-based Payment Arrangement, Option | Share-based Payment Arrangement, Tranche One |  |  |  |  |
Stock compensation |  |  |  |  |
Vesting period (in years) |  |  |  | 1 year |
Share-based Payment Arrangement, Option | Share-based Payment Arrangement, Tranche Two |  |  |  |  |
Stock compensation |  |  |  |  |
Vesting period (in years) |  |  |  | 36 months |
Restricted Stock Units (RSUs) |  |  |  |  |
Stock compensation |  |  |  |  |
Vesting period (in years) |  |  |  | 4 years |
Percentage of units vesting at the end of each calendar year (as a percent) |  |  |  | 25.00% |
Number of shares awarded for each RSU (in shares) |  |  |  | 1 |
Unrecognized compensation cost for nonvested option (in USD per share) | 299.9 |  |  | $ 299.9 |
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years) |  |  |  | 1 year 9 months 18 days |
Performance Shares |  |  |  |  |
Stock compensation |  |  |  |  |
Stock compensation expense | 2.6 | 12.3 |  | $ 12.6 | 19.2
Unrecognized compensation cost for nonvested option (in USD per share) | 43.9 |  |  | $ 43.9 |
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years) |  |  |  | 2 years 4 months 24 days |
Performance Shares | Minimum |  |  |  |  |
Stock compensation |  |  |  |  |
Vesting period (in years) |  |  |  | 3 years |
Performance Shares | Maximum |  |  |  |  |
Stock compensation |  |  |  |  |
Vesting period (in years) |  |  |  | 6 years |
Escient |  |  |  |  |
Stock compensation |  |  |  |  |
Asset acquisition, compensation expense |  |  | $ 31.5 |  | 31.5
Research and Development Expense |  |  |  |  |
Stock compensation |  |  |  |  |
Stock compensation expense | 39.7 | 45.8 |  | $ 114.1 | 117.1
Selling, General and Administrative Expenses |  |  |  |  |
Stock compensation |  |  |  |  |
Stock compensation expense | 21.0 | 31.5 |  | 70.5 | 75.6
Cost of Sales |  |  |  |  |
Stock compensation |  |  |  |  |
Stock compensation expense | $ 0.9 | $ 0.6 |  | $ 2.6 | $ 1.6

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