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License Agreements - Lilly (Details) - USD ($) $ in Thousands	1 Months Ended		3 Months Ended		9 Months Ended		190 Months Ended
	Oct. 31, 2025	Dec. 31, 2009	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025
License Agreements
Total revenues			$ 1,365,980	$ 1,137,871	$ 3,634,407	$ 3,062,519
Eli Lilly | Subsequent Event
License Agreements
Upfront payment received under license agreement	$ 100,000
Eli Lilly | OLUMIANT
License Agreements
Total revenues			$ 37,100	$ 34,800	$ 101,400	$ 97,100
Development Milestones | Eli Lilly
License Agreements
Amount recognized and received for the achievement of a predefined milestone							$ 149,000
Development Milestones | Maximum | Eli Lilly
License Agreements
Upfront and immediate milestone payment to be received under license agreement		$ 150,000
Regulatory Milestones | Eli Lilly
License Agreements
Amount recognized and received for the achievement of a predefined milestone							335,000
Regulatory Milestones | Maximum | Eli Lilly
License Agreements
Upfront and immediate milestone payment to be received under license agreement		365,000
Commercialization Milestones | Eli Lilly
License Agreements
Amount recognized and received for the achievement of a predefined milestone							$ 50,000
Commercialization Milestones | Maximum | Eli Lilly
License Agreements
Upfront and immediate milestone payment to be received under license agreement		$ 150,000

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