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Stock Compensation - Narrative (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Jun. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Stock compensation          
Stock compensation expense $ 61.6 $ 77.9   $ 187.2 $ 194.3
Dividend yield (as percent)       0.00%  
Share-based Payment Arrangement, Option          
Stock compensation          
Stock option grant term (in years)       10 years  
Vesting period (in years)       4 years  
Percentage of units vesting at the end of each calendar year (as a percent)       25.00%  
Unrecognized compensation cost for nonvested option (in USD per share) 25.6     $ 25.6  
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years)       1 year 4 months 24 days  
Share-based Payment Arrangement, Option | Share-based Payment Arrangement, Tranche One          
Stock compensation          
Vesting period (in years)       1 year  
Share-based Payment Arrangement, Option | Share-based Payment Arrangement, Tranche Two          
Stock compensation          
Vesting period (in years)       36 months  
Restricted Stock Units (RSUs)          
Stock compensation          
Vesting period (in years)       4 years  
Percentage of units vesting at the end of each calendar year (as a percent)       25.00%  
Number of shares awarded for each RSU (in shares)       1  
Unrecognized compensation cost for nonvested option (in USD per share) 299.9     $ 299.9  
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years)       1 year 9 months 18 days  
Performance Shares          
Stock compensation          
Stock compensation expense 2.6 12.3   $ 12.6 19.2
Unrecognized compensation cost for nonvested option (in USD per share) 43.9     $ 43.9  
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years)       2 years 4 months 24 days  
Performance Shares | Minimum          
Stock compensation          
Vesting period (in years)       3 years  
Performance Shares | Maximum          
Stock compensation          
Vesting period (in years)       6 years  
Escient          
Stock compensation          
Asset acquisition, compensation expense     $ 31.5   31.5
Research and Development Expense          
Stock compensation          
Stock compensation expense 39.7 45.8   $ 114.1 117.1
Selling, General and Administrative Expenses          
Stock compensation          
Stock compensation expense 21.0 31.5   70.5 75.6
Cost of Sales          
Stock compensation          
Stock compensation expense $ 0.9 $ 0.6   $ 2.6 $ 1.6