v3.25.4

Income Taxes - Schedule of Reconciliation of Income Taxes (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2025 | Dec. 31, 2024 | Dec. 31, 2023
Reconciliation of income taxes at the U.S. federal statutory rate to the provision for income taxes |  |  |
Provision at U.S. federal statutory rate | $ 349,535 | $ 66,492 | $ 175,185
State and local income taxes | 36,394 | 51,753 | 21,145
Foreign tax rate differential | (12,607) | 61,026 | (96,434)
Income tax credits | (59,998) | (70,989) | (1,433,507)
Change in valuation allowance | 123,243 | 21,425 | 1,572,951
Change in uncertain tax positions | 14,208 | 6,418 | 5,943
Foreign-derived intangible income | (34,240) | (31,786) | (32,891)
Stock based compensation |  | 25,647 | 20,971
Acquisitions accounted for as research and development expenses |  | 149,287 | 4,200
Other | (2,973) | 4,742 | (947)
Total provision for income taxes | 377,801 | 284,015 | $ 236,616
Deferred tax assets: |  |  |
Net operating loss carry forwards | 304,075 | 315,969 |
Income tax credits | 1,482,932 | 1,398,495 |
Capitalized research and development | 554,454 | 648,989 |
Deferred revenue and accruals | 96,463 | 190,446 |
Non-cash compensation | 92,482 | 100,788 |
Acquisition-related contingent consideration | 17,426 | 27,796 |
Intangibles, net | 219,005 | 229,741 |
Long term investments | 2,889 | 6,697 |
Other | 24,582 | 20,814 |
Total gross deferred tax assets | 2,794,308 | 2,939,735 |
Less valuation allowance for deferred tax assets | (2,266,136) | (2,139,673) |
Net deferred tax assets | 528,172 | 800,062 |
Deferred tax liabilities: |  |  |
Property and equipment | (7,046) | (30,676) |
Other | (5,832) | (7,315) |
Total gross deferred tax liabilities | (12,878) | (37,991) |
Net deferred tax assets | $ 515,294 | $ 762,071 |

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