v3.25.4

Acquisitions - Narrative (Details) - USD ($) $ in Thousands			1 Months Ended	3 Months Ended	12 Months Ended
	May 30, 2024	Feb. 05, 2024	Jun. 30, 2025	Mar. 31, 2025	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Asset Acquisition [Line Items]
Research and development					$ 2,050,152	$ 2,606,848	$ 1,627,594
Escient
Asset Acquisition [Line Items]
Payments for asset acquisitions	$ 782,500
Asset acquisition, consideration transferred, transaction cost	2,500
Upfront payment	785,000
Asset acquisition, compensation expense						31,500
In-process research and development assets	679,388
Research and development						$ 679,400
Escient | In Process Research and Development - INCB000262
Asset Acquisition [Line Items]
In-process research and development assets	644,800
Escient | In Process Research and Development - INCB000547
Asset Acquisition [Line Items]
In-process research and development assets	$ 34,600
Xencor
Asset Acquisition [Line Items]
Payment to acquire license agreement				$ 12,500
Maximum | Xencor
Asset Acquisition [Line Items]
Uncured material breach, written notice period (in days)		120 days
Payment obligation breach, written notice period (in days)		30 days
Minimum | Xencor
Asset Acquisition [Line Items]
Advance written notice period (in days)		90 days
Regulatory Milestone | Xencor
Asset Acquisition [Line Items]
Milestone payment made under license agreement			$ 25,000
Milestone payment, estimated useful life			8 years
Development and Regulatory Milestones | Maximum | Xencor
Asset Acquisition [Line Items]
Additional milestone payments under the license agreement					145,000
Commercialization Milestones | Maximum | Xencor
Asset Acquisition [Line Items]
Additional milestone payments under the license agreement					$ 50,000
Expiration period (in years)		11 years
MorphoSys AG
Asset Acquisition [Line Items]
Payment to acquire license agreement		$ 25,000

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