v3.25.4

Collaborative and Other Relationships - Lily (Details) - USD ($) $ in Thousands	1 Months Ended		12 Months Ended			193 Months Ended
	Oct. 31, 2025	Dec. 31, 2009	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2025
License agreements
Total revenues			$ 5,141,242	$ 4,241,217	$ 3,695,649
Eli Lilly
License agreements
Upfront payment received under license agreement	$ 100,000					$ 100,000
Eli Lilly | OLUMIANT
License agreements
Total revenues			$ 144,600	$ 135,600	$ 136,100
Development Milestones | Eli Lilly
License agreements
Amount recognized and received for the achievement of a predefined milestone						149,000
Development Milestones | Maximum | Eli Lilly
License agreements
Upfront and immediate milestone payment to be received under license agreement		$ 150,000
Regulatory Milestones | Eli Lilly
License agreements
Amount recognized and received for the achievement of a predefined milestone						335,000
Regulatory Milestones | Maximum | Eli Lilly
License agreements
Upfront and immediate milestone payment to be received under license agreement		365,000
Commercialization Milestones | Eli Lilly
License agreements
Amount recognized and received for the achievement of a predefined milestone						$ 50,000
Commercialization Milestones | Maximum | Eli Lilly
License agreements
Upfront and immediate milestone payment to be received under license agreement		$ 150,000

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