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Fair Value Measurements - Assets Measured at Fair Value on a Recurring Basis (Details) - USD ($) $ in Thousands	Sep. 30, 2023	Dec. 31, 2022
Financial Assets:
Cash and cash equivalents:	$ 441,409	$ 248,859
Amortized Cost or Carrying Value	3,222,056	3,605,208
Amortized Cost or Carrying Value	6,050
Amortized Cost or Carrying Value	3,228,106
Gross Unrealized Gains	154	307
Gross Unrealized Losses Less Than 12 Months	(10,870)	(13,504)
Gross Unrealized Losses More Than 12 Months	(37,898)	(88,694)
Marketable securities, aggregate fair value	3,173,442	3,503,317
Equity securities, aggregate fair value	6,050
Investments, aggregate fair value	3,179,492
Total financial assets	3,669,515	3,854,067
Total financial assets	3,620,901	3,752,176
Level 1
Financial Assets:
Cash and cash equivalents:	418,098	46,610
Marketable securities, aggregate fair value	653,627	617,411
Equity securities, aggregate fair value	6,050
Investments, aggregate fair value	659,677
Total financial assets	1,077,775	664,021
Level 2
Financial Assets:
Cash and cash equivalents:	23,311	202,249
Marketable securities, aggregate fair value	2,519,815	2,885,906
Equity securities, aggregate fair value	0
Investments, aggregate fair value	2,519,815
Total financial assets	2,543,126	3,088,155
Level 3
Financial Assets:
Cash and cash equivalents:	0	0
Marketable securities, aggregate fair value	0	0
Equity securities, aggregate fair value	0
Investments, aggregate fair value	0
Total financial assets	0	0
U.S. Treasury securities
Financial Assets:
Amortized Cost or Carrying Value	528,950	481,463
Gross Unrealized Gains	20	0
Gross Unrealized Losses Less Than 12 Months	(1,060)	(1,269)
Gross Unrealized Losses More Than 12 Months	(3,999)	(11,347)
Marketable securities, aggregate fair value	523,911	468,847
U.S. Treasury securities | Level 1
Financial Assets:
Marketable securities, aggregate fair value	523,911	468,847
U.S. Treasury securities | Level 2
Financial Assets:
Marketable securities, aggregate fair value	0	0
U.S. Treasury securities | Level 3
Financial Assets:
Marketable securities, aggregate fair value	0	0
Non-U.S. government securities
Financial Assets:
Amortized Cost or Carrying Value	115,923	149,901
Gross Unrealized Gains	0	0
Gross Unrealized Losses Less Than 12 Months	0	(33)
Gross Unrealized Losses More Than 12 Months	(2,897)	(6,304)
Marketable securities, aggregate fair value	113,026	143,564
Non-U.S. government securities | Level 1
Financial Assets:
Marketable securities, aggregate fair value	113,026	143,564
Non-U.S. government securities | Level 2
Financial Assets:
Marketable securities, aggregate fair value	0	0
Non-U.S. government securities | Level 3
Financial Assets:
Marketable securities, aggregate fair value	0	0
Corporate debt securities and commercial paper
Financial Assets:
Amortized Cost or Carrying Value	2,577,183	2,973,844
Gross Unrealized Gains	134	307
Gross Unrealized Losses Less Than 12 Months	(9,810)	(12,202)
Gross Unrealized Losses More Than 12 Months	(31,002)	(71,043)
Marketable securities, aggregate fair value	2,536,505	2,890,906
Corporate debt securities and commercial paper | Level 1
Financial Assets:
Marketable securities, aggregate fair value	16,690	5,000
Corporate debt securities and commercial paper | Level 2
Financial Assets:
Marketable securities, aggregate fair value	2,519,815	2,885,906
Corporate debt securities and commercial paper | Level 3
Financial Assets:
Marketable securities, aggregate fair value	0	0
Money market funds
Financial Assets:
Cash and cash equivalents:	418,098	46,610
Money market funds | Level 1
Financial Assets:
Cash and cash equivalents:	418,098	46,610
Money market funds | Level 2
Financial Assets:
Cash and cash equivalents:	0	0
Money market funds | Level 3
Financial Assets:
Cash and cash equivalents:	0	0
Reverse repurchase agreements
Financial Assets:
Cash and cash equivalents:		200,000
Reverse repurchase agreements | Level 1
Financial Assets:
Cash and cash equivalents:		0
Reverse repurchase agreements | Level 2
Financial Assets:
Cash and cash equivalents:		200,000
Reverse repurchase agreements | Level 3
Financial Assets:
Cash and cash equivalents:		0
Commercial paper
Financial Assets:
Cash and cash equivalents:	23,311	2,249
Commercial paper | Level 1
Financial Assets:
Cash and cash equivalents:	0
Commercial paper | Level 2
Financial Assets:
Cash and cash equivalents:	23,311	2,249
Commercial paper | Level 3
Financial Assets:
Cash and cash equivalents:	$ 0

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