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Fair Value Measurements - Assets Measured at Fair Value on a Recurring Basis (Details) - USD ($) $ in Thousands	Mar. 31, 2024	Dec. 31, 2023
Financial Assets:
Cash and cash equivalents:	$ 460,665	$ 408,696
Amortized Cost or Carrying Value	3,157,413	3,353,312
Amortized Cost or Carrying Value	3,935	4,901
Amortized Cost or Carrying Value	3,161,348	3,358,213
Total financial assets	3,622,013	3,766,909
Gross Unrealized Gains	6,796	17,583
Gross Unrealized Losses Less Than 12 Months	(10,396)	(10,936)
Gross Unrealized Losses More Than 12 Months	(3,743)	(8,796)
Marketable securities, aggregate fair value	3,150,070	3,351,163
Equity securities, aggregate fair value	3,935	4,901
Investments, aggregate fair value	3,154,005	3,356,064
Total financial assets	3,614,670	3,764,760
Level 1
Financial Assets:
Cash and cash equivalents:	447,629	408,696
Marketable securities, aggregate fair value	519,477	510,156
Equity securities, aggregate fair value	3,935	4,901
Investments, aggregate fair value	523,412	515,057
Total financial assets	971,041	923,753
Level 2
Financial Assets:
Cash and cash equivalents:	13,036	0
Marketable securities, aggregate fair value	2,630,593	2,841,007
Equity securities, aggregate fair value	0	0
Investments, aggregate fair value	2,630,593	2,841,007
Total financial assets	2,643,629	2,841,007
Level 3
Financial Assets:
Cash and cash equivalents:	0	0
Marketable securities, aggregate fair value	0	0
Equity securities, aggregate fair value	0	0
Investments, aggregate fair value	0	0
Total financial assets	0	0
U.S. Treasury securities
Financial Assets:
Amortized Cost or Carrying Value	437,581	410,665
Gross Unrealized Gains	331	2,162
Gross Unrealized Losses Less Than 12 Months	(665)	(7)
Gross Unrealized Losses More Than 12 Months	(549)	(1,665)
Marketable securities, aggregate fair value	436,698	411,155
U.S. Treasury securities | Level 1
Financial Assets:
Marketable securities, aggregate fair value	436,698	411,155
U.S. Treasury securities | Level 2
Financial Assets:
Marketable securities, aggregate fair value	0	0
U.S. Treasury securities | Level 3
Financial Assets:
Marketable securities, aggregate fair value	0	0
Non-U.S. government securities
Financial Assets:
Amortized Cost or Carrying Value	68,549	83,576
Gross Unrealized Gains	23	55
Gross Unrealized Losses Less Than 12 Months	(20)	(111)
Gross Unrealized Losses More Than 12 Months	(463)	(1,209)
Marketable securities, aggregate fair value	68,089	82,311
Non-U.S. government securities | Level 1
Financial Assets:
Marketable securities, aggregate fair value	68,089	82,311
Non-U.S. government securities | Level 2
Financial Assets:
Marketable securities, aggregate fair value	0	0
Non-U.S. government securities | Level 3
Financial Assets:
Marketable securities, aggregate fair value	0	0
Corporate debt securities and commercial paper
Financial Assets:
Amortized Cost or Carrying Value	2,651,283	2,859,071
Gross Unrealized Gains	6,442	15,366
Gross Unrealized Losses Less Than 12 Months	(9,711)	(10,818)
Gross Unrealized Losses More Than 12 Months	(2,731)	(5,922)
Marketable securities, aggregate fair value	2,645,283	2,857,697
Corporate debt securities and commercial paper | Level 1
Financial Assets:
Marketable securities, aggregate fair value	14,690	16,690
Corporate debt securities and commercial paper | Level 2
Financial Assets:
Marketable securities, aggregate fair value	2,630,593	2,841,007
Corporate debt securities and commercial paper | Level 3
Financial Assets:
Marketable securities, aggregate fair value	0	0
Money market funds
Financial Assets:
Cash and cash equivalents:	447,629	408,696
Money market funds | Level 1
Financial Assets:
Cash and cash equivalents:	447,629	408,696
Money market funds | Level 2
Financial Assets:
Cash and cash equivalents:	0	0
Money market funds | Level 3
Financial Assets:
Cash and cash equivalents:	0	$ 0
Commercial paper
Financial Assets:
Cash and cash equivalents:	13,036
Commercial paper | Level 1
Financial Assets:
Cash and cash equivalents:	0
Commercial paper | Level 2
Financial Assets:
Cash and cash equivalents:	13,036
Commercial paper | Level 3
Financial Assets:
Cash and cash equivalents:	$ 0

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