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                                                                      EXHIBIT 16

                        [Arthur Andersen LLP Letterhead]


June 27, 2002

Office of the Chief Accountant
Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549

Dear Sir or Madam:

The representations made in this letter are based solely on discussions with and
representations from the engagement partner and manager on the audits of the
financial statements of this registrant for the two most recent fiscal years.
Those individuals are no longer with Arthur Andersen LLP. We have read the first
four paragraphs of Item 4 included in the Form 8-K dated June 24, 2002 of
Hologic, Inc. to be filed with the Securities and Exchange Commission and have
found no basis for disagreement with the statements contained therein.

Very truly yours,


/s/ Arthur Andersen LLP

cc: Mr. Glenn P. Muir, Executive Vice President, Finance and Treasurer,
    Hologic, Inc.




