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Revenue - Business Revenue (Details) - USD ($) $ in Millions	12 Months Ended
	Sep. 25, 2021	Sep. 26, 2020	Sep. 28, 2019
Disaggregation of Revenue [Line Items]
Revenues	$ 5,632.3	$ 3,776.4	$ 3,367.3
United States
Disaggregation of Revenue [Line Items]
Revenues	3,902.3	2,863.2	2,536.0
International
Disaggregation of Revenue [Line Items]
Revenues	1,730.0	913.2	831.3
Diagnostics
Disaggregation of Revenue [Line Items]
Revenues	3,695.0	2,102.1	1,205.5
Diagnostics | United States
Disaggregation of Revenue [Line Items]
Revenues	2,393.1	1,582.4	921.3
Diagnostics | International
Disaggregation of Revenue [Line Items]
Revenues	1,301.9	519.7	284.2
Diagnostics | Cytology & Perinatal
Disaggregation of Revenue [Line Items]
Revenues	473.9	410.1	472.0
Diagnostics | Cytology & Perinatal | United States
Disaggregation of Revenue [Line Items]
Revenues	304.6	266.3	312.9
Diagnostics | Cytology & Perinatal | International
Disaggregation of Revenue [Line Items]
Revenues	169.3	143.8	159.1
Diagnostics | Molecular Diagnostics
Disaggregation of Revenue [Line Items]
Revenues	3,171.5	1,648.4	675.0
Diagnostics | Molecular Diagnostics | United States
Disaggregation of Revenue [Line Items]
Revenues	2,038.9	1,272.5	549.9
Diagnostics | Molecular Diagnostics | International
Disaggregation of Revenue [Line Items]
Revenues	1,132.6	375.9	125.1
Diagnostics | Blood Screening
Disaggregation of Revenue [Line Items]
Revenues	49.6	43.6	58.5
Diagnostics | Blood Screening | United States
Disaggregation of Revenue [Line Items]
Revenues	49.6	43.6	58.5
Diagnostics | Blood Screening | International
Disaggregation of Revenue [Line Items]
Revenues	0.0	0.0	0.0
Breast Health
Disaggregation of Revenue [Line Items]
Revenues	1,352.3	1,151.9	1,314.2
Breast Health | United States
Disaggregation of Revenue [Line Items]
Revenues	1,051.8	888.6	1,037.9
Breast Health | International
Disaggregation of Revenue [Line Items]
Revenues	300.5	263.3	276.3
Breast Health | Breast Imaging
Disaggregation of Revenue [Line Items]
Revenues	1,083.4	953.6	1,094.6
Breast Health | Breast Imaging | United States
Disaggregation of Revenue [Line Items]
Revenues	830.4	722.0	853.1
Breast Health | Breast Imaging | International
Disaggregation of Revenue [Line Items]
Revenues	253.0	231.6	241.5
Breast Health | Interventional Breast Solutions
Disaggregation of Revenue [Line Items]
Revenues	268.9	198.3	219.6
Breast Health | Interventional Breast Solutions | United States
Disaggregation of Revenue [Line Items]
Revenues	221.4	166.6	184.8
Breast Health | Interventional Breast Solutions | International
Disaggregation of Revenue [Line Items]
Revenues	47.5	31.7	34.8
Gyn Surgical [Member]
Disaggregation of Revenue [Line Items]
Revenues	488.1	376.1	437.2
Gyn Surgical [Member] | United States
Disaggregation of Revenue [Line Items]
Revenues	396.4	310.1	362.8
Gyn Surgical [Member] | International
Disaggregation of Revenue [Line Items]
Revenues	91.7	66.0	74.4
Skeletal Health
Disaggregation of Revenue [Line Items]
Revenues	96.9	81.0	94.8
Skeletal Health | United States
Disaggregation of Revenue [Line Items]
Revenues	61.0	51.2	58.6
Skeletal Health | International
Disaggregation of Revenue [Line Items]
Revenues	35.9	29.8	36.2
Medical Aesthetics
Disaggregation of Revenue [Line Items]
Revenues	0.0	65.3	315.6
Medical Aesthetics | United States
Disaggregation of Revenue [Line Items]
Revenues	0.0	30.9	155.4
Medical Aesthetics | International
Disaggregation of Revenue [Line Items]
Revenues	$ 0.0	$ 34.4	$ 160.2

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