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Consolidated Statements of Changes in Stockholders' Equity - USD ($)
Preferred Stock
Common Stock [Member]
Additional Paid-In Capital [Member]
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit [Member]
Total
Balances at beginning at Dec. 31, 2016 $ 6 $ 40,000 $ 64,208,963 $ (53,354,332) $ 10,894,637
Balances at beginning (in shares) at Dec. 31, 2016 6,380 39,999,784        
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Issuance of common stock pursuant to private placement   $ 3,333 9,996,615     9,999,948
Issuance of common stock pursuant to private placement (in shares)   3,333,329        
Issuance of common stock in exchange of service   $ 94 327,903     327,997
Issuance of common stock in exchange of service (in shares)   94,252        
Issuance of common stock pursuant to exercise of stock options   $ 1,942 944,633     946,575
Issuance of common stock pursuant to exercise of stock options (in shares)   1,940,895        
Issuance of common stock in exchange of convertible note   $ 333 999,666     999,999
Issuance of common stock in exchange of convertible note (in shares)   333,333        
Issuance of preferred stock for conversion of accrued dividends $ 1   382,999     383,000
Issuance of preferred stock for conversion of accrued dividends (in shares) 380          
Stock option expense     2,241,045     2,241,045
Debt Extinguishment Beneficial Conversion Feature          
Foreign currency translation loss       (39,378)   (39,378)
Preferred stock dividend - other         (365,995) (365,995)
Net loss         (8,240,583) (8,240,583)
Balances at ending at Dec. 31, 2017 $ 7 $ 45,702 79,101,824 $ (39,378) (61,960,910) 17,147,245
Balances at ending (in shares) at Dec. 31, 2017 6,760 45,701,593        
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Preferred stock C - conversion to common stock $ (3) $ 5,806       5,803
Preferred stock C - conversion to common stock (in shares) (3,016) 5,806,022        
Preferred stock D- conversion to common stock $ (4) $ 4,651 $ (10,450)     (5,803)
Preferred stock D- conversion to common stock (in shares) (4,000) 4,651,163        
Issuance of common stock pursuant to exercise of stock options - Cashless (in shares)   313,008 313 (313)    
Beneficial Conversion Feature on Convertible Instruments     $ 555,066     555,066
Issuance of common stock in exchange of service   $ 60 279,540     279,600
Issuance of common stock in exchange of service (in shares)   60,000        
Issuance of common stock pursuant to exercise of stock options   $ 471 301,252     $ 301,723
Issuance of common stock pursuant to exercise of stock options (in shares)   470,722       784,000
Issuance of preferred stock for conversion of accrued dividends     255,903     $ 255,903
Issuance of preferred stock for conversion of accrued dividends (in shares) 256          
Stock option expense     4,293,797     4,293,797
Debt Extinguishment Beneficial Conversion Feature     377,048     377,048
Foreign currency translation loss       $ 12,381   12,381
Preferred stock dividend - other         (213,133) (213,133)
Net loss         (11,206,648) (11,206,648)
Balances at ending at Dec. 31, 2018 $ 57,003 $ 85,153,667 $ (26,997) $ (73,380,691) $ 11,802,982
Balances at ending (in shares) at Dec. 31, 2018 57,002,508