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Income Tax (Tables) | 12 Months Ended
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Dec. 31, 2021
Income Tax Disclosure [Abstract] |
Components of loss before income taxes | The components of the Company's loss before income taxes are as follows:
|  | Year Ended December 31, 2021 |  | Year Ended December 31, 2020 |
United Kingdom |  | $ | (72,244) |  |  | $ | (51,197) |  |
United States |  | (16,358) |  |  | (1,713) |  |
Loss before income taxes |  | $ | (88,602) |  |  | $ | (52,910) |  |
Significant components of the provision for income taxes | Significant components of the provision for income taxes are as follows:
| Year Ended December 31, 2021 |  | Year Ended December 31, 2020 |
Current income tax benefit: |  |  |  |
Federal United States | $ | — |  |  | $ | (215) |  |
State - United States | — |  |  | 2 |  |
Non-United States | — |  |  | — |  |
Total | — |  |  | (213) |  |
Federal - United States | — |  |  | — |  |
State - United States | — |  |  | — |  |
Non-United States | — |  |  | — |  |
Total deferred tax | — |  |  | — |  |
Total income tax benefit | $ | — |  |  | $ | (213) |  |
Major components of deferred tax assets and liabilities | The major components of deferred tax assets and liabilities are as follows:
| December 31, 2021 |  | December 31, 2020
Deferred tax assets: |  |  |
Net operating loss carryforward | $ | 49,422 |  |  | $ | 29,831 |
Research and development credit carryforward | 941 |  |  | — |
Stock based compensation | 2,560 |  |  | 1,167
Other | 1,477 |  |  | 491
Total deferred tax assets | 54,400 |  |  | 31,489
Deferred tax liabilities: |  |  |
Intangible asset | (2,600) |  | (2,189)
Other | (54) |  | (71)
Total deferred tax liabilities | (2,654) |  | (2,260)
Net deferred tax assets before valuation allowance | 51,746 |  | 29,229
Valuation allowance | (51,746) |  | (29,229)
Deferred tax, net | $ | — |  |  | $ | — |
Reconciliation of the effective income tax rate to the statutory rate | A reconciliation of the Company's effective tax rate to the U.S. federal statutory rate is as follows:
|  | Year Ended December 31, 2021 |  | Year Ended December 31, 2020 |
U.S. federal income tax statutory rate |  | 21.0 | % |  | 21.0 | % |
Change in valuation allowance |  | (10.5) | % |  | (12.1) | % |
Non-deductible expenses |  | (0.4) | % |  | (3.9) | % |
Refundable research and development tax credit |  | (8.3) | % |  | (7.0) | % |
Effect of foreign operations taxed at various rates |  | 0.5 | % |  | 0.9 | % |
Stock-based compensation |  | (1.6) | % |  | — | % |
Other |  | (0.7) | % |  | 1.4 | % |
|  | — | % |  | 0.30 | % |

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- Definition Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 9 -URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32639-109319 + Details
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- Definition Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32537-109319 + Details
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- Definition Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32687-109319 + Details
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