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Income Tax - Reconciliation of the effective income tax rate to statutory rate (Details) | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020
Income Tax Disclosure [Abstract] |  |
U.S. federal income tax statutory rate | 21.00% | 21.00%
Change in valuation allowance | (10.50%) | (12.10%)
Non-deductible expenses | (0.40%) | (3.90%)
Refundable research and development tax credit | (8.30%) | (7.00%)
Effect of foreign operations taxed at various rates | 0.50% | 0.90%
Stock-based compensation | (1.60%) | 0.00%
Other | (0.70%) | 1.40%
Effective tax rate | 0.00% | 0.30%

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- Definition Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32687-109319 + Details
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- Definition Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to changes in the valuation allowance for deferred tax assets. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 6.I.Fact.4) -URI http://asc.fasb.org/extlink&oid=122134291&loc=d3e330036-122817 Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32687-109319 + Details
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