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    <ACCEPTANCE-DATETIME>20230120165551
    ACCESSION NUMBER:		0001599298-23-000012
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		60
    CONFORMED PERIOD OF REPORT:	20230116
    ITEM INFORMATION:		Entry into a Material Definitive Agreement
    ITEM INFORMATION:		Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers
    ITEM INFORMATION:		Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year
    ITEM INFORMATION:		Other Events
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20230120
    DATE AS OF CHANGE:		20230120

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Summit Therapeutics Inc.
    		CENTRAL INDEX KEY:			0001599298
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-36866
    		FILM NUMBER:		23541641

    	BUSINESS ADDRESS:
    		STREET 1:		2882 SAND HILL ROAD
    		STREET 2:		SUITE 106
    		CITY:			MENLO PARK
    		STATE:			CA
    		ZIP:			94025
    		BUSINESS PHONE:		617-514-7149

    	MAIL ADDRESS:
    		STREET 1:		2882 SAND HILL ROAD
    		STREET 2:		SUITE 106
    		CITY:			MENLO PARK
    		STATE:			CA
    		ZIP:			94025

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Summit Therapeutics plc
    		DATE OF NAME CHANGE:	20150219

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Summit Corp plc
    		DATE OF NAME CHANGE:	20140205
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