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Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2023 | Dec. 31, 2022
Cash flows used in operating activities: |  |
Net loss | $ (614,928) | $ (78,782)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Gain on remeasurement of liabilities | 0 | (1,265)
Non-cash interest expense | 6,253 | 4,303
Amortization of discount on short-term investments | (1,924) | 0
Unrealized foreign currency (gain) loss | (812) | 2,616
Reclassification of currency translation gain | (419) | 0
Impairment of fixed assets | 474 | 0
Amortization of operating right-of-use assets | 1,852 | 1,251
Depreciation | 198 | 349
Amortization of intangible assets | 0 | 914
Impairment of intangible assets | 0 | 8,468
Stock-based compensation | 14,108 | 11,948
Loss on disposal of assets | (109) | 0
In-process research and development expense | 520,915 | 0
Changes in operating assets and liabilities: |  |
Accounts receivable | 359 | 975
Prepaid expenses | (914) | 5,107
Other current and long-term assets | (3,421) | 215
Research and development tax credit receivable | 4,168 | 8,437
Deferred revenue and other income | 0 | (7,278)
Accounts payable | 2,263 | (4,132)
Accrued liabilities | (2,377) | 4,782
Accrued compensation | (235) | 1,609
Operating lease liabilities | (2,211) | (1,099)
Net cash used in operating activities | (76,760) | (41,582)
Cash flows used in investing activities: |  |
Purchase of property and equipment | (128) | (624)
Proceeds from sale of property. plant and equipment | 226 | 0
Purchase of short-term investments | (321,022) | 0
Maturities and sales of short-term investments | 208,165 | 0
Payments to Akeso for upfront milestone payments and associated direct transaction costs | (475,015) | 0
Net cash used in investing activities | (587,774) | (624)
Cash flows provided by financing activities: |  |
Proceeds from the issuance of common stock for rights offering | 104,686 | 100,000
Transaction costs from the issuance of common stock for rights offering | (619) | (111)
Proceeds from the issuance of common stock via private placement | 5,000 | 0
Net receipts related to the exercise of warrants | 1,203 | 0
Proceeds received related to employee stock purchase plan and exercise of stock options | 929 | 399
Proceeds from related party promissory notes | 0 | 545,000
Re-payment of related party promissory notes | (24,686) | (25,000)
Payments of related party promissory notes issuance costs | 0 | (44)
Net cash provided by financing activities | 86,513 | 620,244
Effect of exchange rates on cash and cash equivalents | 839 | (1,222)
(Decrease) Increase in cash, cash equivalents and restricted cash | (577,182) | 576,816
Cash, cash equivalents and restricted cash at beginning of period | 648,607 | 71,791
Cash, cash equivalents and restricted cash at end of period | 71,425 | 648,607
Cash paid for interest on related party promissory note | 10,650 | 434
Cash paid for income taxes | 52 | 0
Debt issuance costs in accrued expenses | 0 | 31
Deferred transaction costs included in other non-current assets | 0 | 425
Leased assets obtained in exchange for operating lease liabilities | 4,245 | 2,860
Akeso License Agreement |  |
Issuance of common stock | 45,900 | 0
Rights Offering |  |
Issuance of common stock | $ 395,314 | $ 0

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