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v3.25.4

Related Party Transactions (Details) $ / shares in Units, $ in Thousands |  |  |  |  |  |  | 1 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Oct. 21, 2025 shares | Apr. 08, 2025 $ / shares shares | Sep. 11, 2024 shares | Aug. 01, 2024 ft² | Jun. 03, 2024 shares | Apr. 01, 2024 USD ($) ft² contract | Mar. 31, 2025 $ / shares shares | Oct. 31, 2024 shares | Dec. 31, 2025 USD ($) $ / shares shares | Dec. 31, 2024 USD ($) $ / shares | Dec. 31, 2023 USD ($) | Jul. 29, 2022 ft² | Jul. 25, 2022 ft²
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Research and development | [1] |  |  |  |  |  |  |  |  | $ 537,674 | $ 150,777 | $ 59,471 |  |
Accrued liabilities |  |  |  |  |  |  |  |  |  | $ 32,100 | $ 19,554 |  |  |
Exercised (in shares) | shares |  |  |  |  |  |  |  |  |  | 4,629,988 |  |  |  |
Shares issued (in shares) | shares |  |  |  |  |  | 22,222,222 |  |  |  |  |  |  |  |
Warrant weighted average exercise price (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  | $ 1.58 |  |  |
Exercised (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  | $ 1.58 |  |  |  |
Private placement |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued (in shares) | shares |  | 26,682,846 |  | 10,352,418 |  |  |  |  |  |  |  |  |  |
Related party |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued (in shares) | shares |  | 533,617 |  |  |  |  |  |  |  |  |  |  |  |
Affiliated entity |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of sublease contracts to other party | contract |  |  |  |  |  |  | 2 |  |  |  |  |  |  |
Shares issued (in shares) | shares |  | 14,514,402 |  |  |  |  |  |  |  |  |  |  |  |
Co-Chief Executive Officer |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Exercised (in shares) | shares |  |  | 1,048,834 |  |  |  |  | 2,936,221 |  |  |  |  |  |
Warrant weighted average exercise price (in dollars per share) | $ / shares |  |  |  |  |  |  |  | $ 1.58 |  |  |  |  |  |
Exercised (in dollars per share) | $ / shares |  |  | $ 1.58 |  |  |  |  |  |  |  |  |  |  |
Co-Chief Executive Officer | Private placement |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued (in shares) | shares |  |  |  |  |  |  |  | 3,985,055 |  |  |  |  |  |
Wilson Sonsini Goodrich & Rosati P.C. (“WSGR”) |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Legal fees |  |  |  |  |  |  |  |  |  | $ 1,400 |  |  |  |
Sublease Agreement, First and Third Amendment | Affiliated entity |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments to related party |  |  |  |  |  |  |  |  |  | 834 | $ 795 | 762 |  |
First amendment to sublease | Affiliated entity |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Area of premises subleased (in square feet) | ft² |  |  |  |  |  |  |  |  |  |  |  |  |  | 4,500
Sublease extension term (in months) |  |  |  |  |  |  |  |  |  |  |  |  |  | 39 months
Sublease Agreement, Third Amendment | Affiliated entity |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Area of premises subleased (in square feet) | ft² |  |  |  |  | 145 |  |  |  |  |  |  |  |  |
Proportionate share of net payable |  |  |  |  | 93.60% |  |  |  |  |  |  |  |  |
Second amendment to sublease | Affiliated entity |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Area of premises subleased (in square feet) | ft² |  |  |  |  |  |  |  |  |  |  |  |  | 1,277 |
Payments to related party |  |  |  |  |  |  |  |  |  | 232 | 224 | 218 |  |
Genius Sublease Agreement | Affiliated entity |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of sublease contracts to other party | contract |  |  |  |  |  |  | 1 |  |  |  |  |  |  |
Area of premises subleased to other party (in square feet) | ft² |  |  |  |  |  |  | 848 |  |  |  |  |  |  |
Sublease term to other party (in months) |  |  |  |  |  |  | 62 months |  |  |  |  |  |  |
Total sublease rental payments to be received |  |  |  |  |  |  | $ 446 |  |  |  |  |  |  |
Investments Research Sublease Agreement | Affiliated entity |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of sublease contracts to other party | contract |  |  |  |  |  |  | 1 |  |  |  |  |  |  |
Area of premises subleased to other party (in square feet) | ft² |  |  |  |  |  |  | 848 |  |  |  |  |  |  |
Sublease term to other party (in months) |  |  |  |  |  |  | 62 months |  |  |  |  |  |  |
Total sublease rental payments to be received |  |  |  |  |  |  | $ 446 |  |  |  |  |  |  |
Genius Sublease Agreement And Investments Research Sublease Agreement | Affiliated entity |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Sublease income |  |  |  |  |  |  |  |  |  | 186 | 156 |  |  |
Akeso Supply Agreement | Related party |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  |  |  |  |  | 46,133 | 24,635 | $ 6,207 |  |
Accrued liabilities |  |  |  |  |  |  |  |  |  | $ 1,215 | $ 3,956 |  |  |
Consulting Agreement | Affiliated entity |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Exercised (in shares) | shares |  |  |  |  |  |  |  |  | 315,681 |  |  |  |  |
[1] | Refer to Note 15 – Related Party Transactions for expenses incurred.

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