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Segments and Geographic Data - Summary of Net Long-lived Assets Consisting of Property and Equipment (Details) - USD ($) $ in Millions | Jan. 02, 2022 | Jan. 03, 2021
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Revenues from External Customers and Long-Lived Assets [Line Items] |  |
Total net long-lived assets | $ 1,696 | $ 1,454
United States |  |
Revenues from External Customers and Long-Lived Assets [Line Items] |  |
Total net long-lived assets | 1,281 | 1,134
Singapore |  |
Revenues from External Customers and Long-Lived Assets [Line Items] |  |
Total net long-lived assets | 218 | 150
United Kingdom |  |
Revenues from External Customers and Long-Lived Assets [Line Items] |  |
Total net long-lived assets | 146 | 141
Other countries |  |
Revenues from External Customers and Long-Lived Assets [Line Items] |  |
Total net long-lived assets | $ 51 | $ 29

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- Definition Property, Plant And Equipment, Net And Operating Lease, Right-Of-Use Assets + References No definition available. + Details
Name: | ilmn_PropertyPlantAndEquipmentNetAndOperatingLeaseRightOfUseAssets
Namespace Prefix: | ilmn_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

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- Details
Name: | srt_StatementGeographicalAxis=country_US
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | srt_StatementGeographicalAxis=country_SG
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | srt_StatementGeographicalAxis=country_GB
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | srt_StatementGeographicalAxis=ilmn_OtherCountriesMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |