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Consolidated Statements of Income - USD ($)
shares in Millions, $ in Millions
 12 Months Ended
Jan. 02, 2022
Jan. 03, 2021
Dec. 29, 2019
Revenue:      
Total revenue $ 4,526 $ 3,239 $ 3,543
Cost of revenue:      
Amortization of acquired intangible assets 71 28 34
Total cost of revenue 1,372 1,036 1,076
Gross profit 3,154 2,203 2,467
Operating expense:      
Research and development 1,185 682 647
Selling, general and administrative 2,092 941 835
Total operating expense 3,277 1,623 1,482
(Loss) income from operations (123) 580 985
Other income (expense):      
Interest income 0 41 75
Interest expense (61) (49) (52)
Other income, net 1,068 284 110
Total other income, net 1,007 276 133
Income before income taxes 884 856 1,118
Provision for income taxes 122 200 128
Consolidated net income 762 656 990
Add: Net loss attributable to noncontrolling interests 0 0 12
Net income attributable to Illumina stockholders $ 762 $ 656 $ 1,002
Earnings per share attributable to Illumina stockholders:      
Basic (in dollars per share) $ 5.07 $ 4.48 $ 6.81
Diluted (in dollars per share) $ 5.04 $ 4.45 $ 6.74
Shares used in computing earnings per share:      
Basic (in shares) 150 147 147
Diluted (in shares) 151 148 149
Product revenue      
Revenue:      
Total revenue $ 3,968 $ 2,735 $ 2,929
Cost of revenue:      
Cost of revenue 1,060 788 802
Service and other revenue      
Revenue:      
Total revenue 558 504 614
Cost of revenue:      
Cost of revenue $ 241 $ 220 $ 240