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Stockholders' Equity - Narrative- Share-based Compensation (Details)
$ in Millions
1 Months Ended 12 Months Ended
Feb. 28, 2021
USD ($)
employee
Aug. 31, 2020
employee
Jan. 02, 2022
USD ($)
Jan. 03, 2021
USD ($)
Dec. 29, 2019
USD ($)
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense, before taxes     $ 941 $ 194 $ 194
Research and development          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense, before taxes     276 74 66
Selling, general and administrative          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based compensation expense, before taxes     638 95 $ 105
GRAIL Inc          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based payment arrangement, accelerated cost     615    
Replacement Awards | GRAIL Inc          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based payment arrangement, accelerated cost     615    
Share-based compensation expense, before taxes     24    
Replacement Awards | GRAIL Inc | Research and development          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based payment arrangement, accelerated cost     167    
Replacement Awards | GRAIL Inc | Selling, general and administrative          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share-based payment arrangement, accelerated cost     $ 448    
PSU          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share based compensation vesting performance period 3 years 3 years 3 years    
Number of employees effected by modification | employee   49      
Incremental share-based compensation cost       $ 47  
Performance Shares, Granted In 2019          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Number of employees effected by modification | employee 52        
Incremental share-based compensation cost $ 41        
Performance Shares, Granted In 2020          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Number of employees effected by modification | employee 72        
Incremental share-based compensation cost $ 65