    <SEC-DOCUMENT>0001193125-22-105650-index.html : 20220414
    <SEC-HEADER>0001193125-22-105650.hdr.sgml : 20220414
    <ACCEPTANCE-DATETIME>20220414163232
    ACCESSION NUMBER:		0001193125-22-105650
    CONFORMED SUBMISSION TYPE:	DEFA14A
    PUBLIC DOCUMENT COUNT:		3
    FILED AS OF DATE:		20220414
    DATE AS OF CHANGE:		20220414

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ILLUMINA, INC.
    		CENTRAL INDEX KEY:			0001110803
    		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
    		IRS NUMBER:				330804655
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			0101

    	FILING VALUES:
    		FORM TYPE:		DEFA14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-35406
    		FILM NUMBER:		22827703

    	BUSINESS ADDRESS:
    		STREET 1:		5200 ILLUMINA WAY
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92122
    		BUSINESS PHONE:		8582024500

    	MAIL ADDRESS:
    		STREET 1:		5200 ILLUMINA WAY
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92122

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ILLUMINA INC
    		DATE OF NAME CHANGE:	20000331
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEFA14A
    <SEQUENCE>1
    <FILENAME>d348359ddefa14a.htm
    <DESCRIPTION>DEFA14A
    <TEXT>
    Document 1 - file: d348359ddefa14a.htm

    </DOCUMENT>
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    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>g348359g01m41.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: g348359g01m41.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>g348359g01m42.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: g348359g01m42.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>