<SEC-DOCUMENT>0001539497-23-000754.txt : 20230427
<SEC-HEADER>0001539497-23-000754.hdr.sgml : 20230427
<ACCEPTANCE-DATETIME>20230427161702
ACCESSION NUMBER:		0001539497-23-000754
CONFORMED SUBMISSION TYPE:	DEFC14A
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20230427
DATE AS OF CHANGE:		20230427

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ILLUMINA, INC.
		CENTRAL INDEX KEY:			0001110803
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				330804655
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEFC14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-35406
		FILM NUMBER:		23857187

	BUSINESS ADDRESS:	
		STREET 1:		5200 ILLUMINA WAY
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92122
		BUSINESS PHONE:		8582024500

	MAIL ADDRESS:	
		STREET 1:		5200 ILLUMINA WAY
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92122

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ILLUMINA INC
		DATE OF NAME CHANGE:	20000331

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ICAHN CAPITAL LP
		CENTRAL INDEX KEY:			0001412093
		IRS NUMBER:				000000000

	FILING VALUES:
		FORM TYPE:		DEFC14A

	BUSINESS ADDRESS:	
		STREET 1:		16690 COLLINS AVE.
		STREET 2:		PH-1
		CITY:			SUNNY ISLES BEACH
		STATE:			FL
		ZIP:			33160
		BUSINESS PHONE:		305-422-4145

	MAIL ADDRESS:	
		STREET 1:		16690 COLLINS AVE.
		STREET 2:		PH-1
		CITY:			SUNNY ISLES BEACH
		STATE:			FL
		ZIP:			33160

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ICAHN PARTNERS HOLDING LP
		DATE OF NAME CHANGE:	20070911
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEFC14A
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<FILENAME>n2779_x128-defc14a.htm
<DESCRIPTION>DEFC14A
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>UNITED STATES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Washington, D.C. 20549</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>SCHEDULE 14A</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">Proxy Statement Pursuant to Section 14(a) of the Securities
Exchange Act of 1934</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Filed by the Registrant <FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Filed by a Party other than the Registrant <FONT STYLE="font-family: Times New Roman, Times, Serif">&#9746;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Check the appropriate box:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="vertical-align: top; padding-bottom: 6pt; padding-left: 8pt; text-indent: -8pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="vertical-align: bottom; padding-bottom: 6pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding-bottom: 6pt"><FONT STYLE="font-size: 10pt">Preliminary Proxy Statement</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding-bottom: 6pt; padding-left: 8pt; text-indent: -8pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="vertical-align: bottom; padding-bottom: 6pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding-bottom: 6pt"><FONT STYLE="font-size: 10pt"><B>Confidential, for Use of the Commission Only&nbsp;(as permitted by Rule 14-a6(e)(2))</B></FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding-bottom: 6pt; padding-left: 8pt; text-indent: -8pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9746;</FONT></TD>
    <TD STYLE="vertical-align: bottom; padding-bottom: 6pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding-bottom: 6pt"><FONT STYLE="font-size: 10pt">Definitive Proxy Statement</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding-bottom: 6pt; padding-left: 8pt; text-indent: -8pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="vertical-align: bottom; padding-bottom: 6pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding-bottom: 6pt"><FONT STYLE="font-size: 10pt">Definitive Additional Materials</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding-bottom: 6pt; padding-left: 8pt; text-indent: -8pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="vertical-align: bottom; padding-bottom: 6pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding-bottom: 6pt"><FONT STYLE="font-size: 10pt">Soliciting Material Pursuant to &sect;240.14a-12</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 14pt; background-color: white"><B>ILLUMINA,
INC.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">(Name of Registrant as Specified In Its Charter)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>ICAHN
PARTNERS LP</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>ICAHN
ONSHORE LP</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>ICAHN
PARTNERS MASTER FUND LP</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>ICAHN
OFFSHORE LP</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>ICAHN
CAPITAL LP</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>IPH
GP LLC</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>ICAHN
ENTERPRISES HOLDINGS L.P.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>ICAHN
ENTERPRISES G.P. INC.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>BECKTON
CORP.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>Matsumura
Fishworks LLC</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>CARL
C. ICAHN</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>Vincent
J. Intrieri</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>Jesse
A. Lynn</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; background-color: white"><FONT STYLE="font-size: 12pt; text-transform: uppercase"><B>Andrew
J. Teno</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">(Name of Person(s) Filing Proxy Statement, if other
than the Registrant)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; background-color: white">Payment of Filing Fee (check all boxes
that apply):</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; background-color: white">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; background-color: white; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 4%; line-height: 106%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">&#9746;</FONT></TD>
    <TD STYLE="line-height: 106%"><FONT STYLE="font-size: 10pt; line-height: 106%">No fee required.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; background-color: white">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; background-color: white; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 4%; line-height: 106%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">&#9744;</FONT></TD>
    <TD STYLE="line-height: 106%"><FONT STYLE="font-size: 10pt; line-height: 106%">Fee paid previously with preliminary materials.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; background-color: white">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; background-color: white; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 4%; line-height: 106%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; line-height: 106%">&#9744;</FONT></TD>
    <TD STYLE="line-height: 106%"><FONT STYLE="font-size: 10pt; line-height: 106%">Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules&nbsp;14a-6(i)(1)&nbsp;and&nbsp;0-11.</FONT></TD></TR>
  </TABLE>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; background-color: white"><B>ICAHN CAPITAL LP<BR>
<BR>
</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 12pt; text-align: center">April 27, 2023</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Dear Fellow Stockholders:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify"><FONT STYLE="background-color: white">We are
furnishing the attached proxy statement to holders of </FONT>the shares of common stock, par value $0.01 per share (the &ldquo;<U>Shares</U>&rdquo;),
<FONT STYLE="background-color: white">of Illumina, Inc., a Delaware corporation (&ldquo;<U>Illumina</U>&rdquo; or the &ldquo;<U>Company</U>&rdquo;),
in connection with our solicitation of proxies for use at the 2023 Annual Meeting of Stockholders of the Company scheduled to be held
virtually on </FONT>May 25, 2023 at 10:00 a.m. (Pacific time) <FONT STYLE="background-color: white">and at any and all adjournments, continuations
or postponements thereof (the &ldquo;<U>Annual Meeting</U>&rdquo;).</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify"><FONT STYLE="background-color: white">This
solicitation is being conducted by Icahn Partners LP (&ldquo;<U>Icahn Partners</U>&rdquo;), Icahn Partners Master Fund LP (&ldquo;<U>Icahn
Master</U>&rdquo;), Icahn Onshore LP (&ldquo;<U>Icahn Onshore</U>&rdquo;), Icahn Offshore LP (&ldquo;<U>Icahn Offshore</U>&rdquo;), Icahn
Capital LP (&ldquo;<U>Icahn Capital</U>&rdquo;), IPH GP LLC (&ldquo;<U>IPH GP</U>&rdquo;), Icahn Enterprises Holdings L.P. (&ldquo;<U>Icahn
Holdings</U>&rdquo;), </FONT>Icahn Enterprises G.P. Inc. (&ldquo;<U>Icahn Enterprises GP</U>&rdquo;), Beckton Corp. (&ldquo;<U>Beckton</U>&rdquo;),
Matsumura Fishworks LLC, an Ohio limited liability company (&ldquo;<U>Matsumura</U>&rdquo;), and <FONT STYLE="background-color: white">Carl
C. Icahn (&ldquo;<U>Mr. Icahn</U>&rdquo;, together with Icahn Partners, Icahn Master, Icahn Onshore, Icahn Offshore, Icahn Capital, IPH
GP, Icahn Holdings, Icahn Enterprises GP, </FONT>Matsumura<FONT STYLE="background-color: white">, and Beckton, the &ldquo;<U>Icahn Participants</U>&rdquo;
or &ldquo;<U>we</U>&rdquo;), as well as Vincent J. Intrieri, Jesse A. Lynn, and Andrew J. Teno (collectively, the &ldquo;<U>Icahn Nominees</U>&rdquo;
and together with the Icahn Participants, the &ldquo;<U>Participants</U>&rdquo;). As of the Record Date, the Icahn Participants beneficially
own in the aggregate 2,198,853 Shares, which represent approximately 1.4% of the outstanding Shares (based upon 158,032,030 Shares stated
to be outstanding as of the Record Date by the Company in its proxy statement filed with the Securities and Exchange Commission (the &ldquo;<U>SEC</U>&rdquo;)
on </FONT>April 20<FONT STYLE="background-color: white">, 2023.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify"><FONT STYLE="background-color: white">As more
fully discussed in this Proxy Statement, we are soliciting proxies to be used at the Annual Meeting for the following items:</FONT></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 12pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">(1)</TD><TD STYLE="text-align: justify"><FONT STYLE="background-color: white">To elect each of the Icahn Nominees as directors of Illumina; </FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 12pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">(2)</TD><TD STYLE="text-align: justify">Ratify the appointment of Ernst&nbsp;&amp; Young LLP as Illumina&rsquo;s independent registered public
accounting firm for the fiscal year ending December 31, 2023;</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 12pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">(3)</TD><TD STYLE="text-align: justify"><FONT STYLE="background-color: white">Hold an advisory vote to approve the compensation provided to the
&ldquo;named executive officers&rdquo; of Illumina, as disclosed in the Company&rsquo;s proxy statement </FONT>filed with the SEC;</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 12pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">(4)</TD><TD STYLE="text-align: justify"><FONT STYLE="background-color: white">Hold an advisory vote to approve the frequency on holding an advisory
vote to approve compensation provided to the Company&rsquo;s &ldquo;named executive officers&rdquo;;</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 12pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">(5)</TD><TD STYLE="text-align: justify"><FONT STYLE="background-color: white">Hold a vote to approve certain amendments to the Illumina, Inc.
2015 Stock and Incentive Plan; and</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 12pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">(6)</TD><TD STYLE="text-align: justify"><FONT STYLE="background-color: white">Transact such other business as may properly come before the meeting
and any adjournment or postponement thereof.</FONT></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt"><FONT STYLE="background-color: white"><B>THIS SOLICITATION IS BEING
MADE BY THE PARTICIPANTS AND NOT ON BEHALF OF THE BOARD OF DIRECTORS OF ILLUMINA.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">We urge you to elect
the Icahn Nominees to the Board of Directors of Illumina (the &ldquo;<U>Board</U>&rdquo;) because, as further discussed in this Proxy
Statement, we believe that the election of new members to the Board would be beneficial to the Company and all of its stockholders. We
believe that the Icahn Nominees are immensely qualified in terms of utility and regulatory experience and reflect a diverse mix of operational,
financial, legal, regulatory and governance experts.</P>


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    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">According to publicly
available information, the current Board consists of 9 directors whose terms will expire at the Annual Meeting. <FONT STYLE="background-color: white">The
Company&rsquo;s Amended and Restated Bylaws (the &ldquo;<U>Bylaws</U>&rdquo;) </FONT>provide that members of the Board are to be elected
at each annual meeting of stockholders. We are soliciting proxies in support of the Icahn Nominees.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">We have determined
to nominate&nbsp;<B>Vincent J. Intrieri</B>, <FONT STYLE="background-color: white"><B>Jesse A. Lynn</B>, and <B>Andrew J. Teno</B></FONT>
to the Board. As a result, should a stockholder so authorize us, on the&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy card, we would cast
votes &ldquo;<B><U>FOR</U></B>&rdquo; the election of all of the Icahn Nominees.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><I>Stockholders of
Record:</I> If your Shares are held in your own name, please authorize a proxy to vote by signing and returning the enclosed&nbsp;<B><U>GOLD</U>&nbsp;</B>universal
proxy card using the postage-paid envelope provided.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><I>Street-Name Holders:
</I>If your Shares are held in the name of a bank, brokerage firm, dealer, trust company or other custodian, only that firm can vote such
Shares and, with respect to the election of directors, only upon receipt of your specific instruction. Accordingly, we urge you to complete,
sign, date and return the enclosed <B><U>GOLD</U></B> voting instruction form using the postage-paid envelope provided by your broker
or bank custodian or vote via the Internet by following the directions provided to you by your broker or bank custodian or contact the
person responsible for your account and instruct that person to execute the&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy card on your
behalf. Please follow any voting instructions provided by your bank, brokerage firm, dealer, trust company or other custodian.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>IF YOU ARE A STOCKHOLDER OF RECORD AND ALREADY
HAVE VOTED USING THE COMPANY&rsquo;S WHITE PROXY CARD OR VIA THE INTERNET BY FOLLOWING THE INSTRUCTIONS PROVIDED TO YOU BY THE COMPANY,
YOU MAY REVOKE YOUR PREVIOUSLY SUBMITTED WHITE PROXY BY SIGNING AND RETURNING A LATER-DATED&nbsp;<U>GOLD</U> UNIVERSAL PROXY CARD USING
THE ENCLOSED POSTAGE-PAID ENVELOPE, OR BY DELIVERING A WRITTEN NOTICE OF REVOCATION TO THE COMPANY OR TO THE SECRETARY OF THE COMPANY.
ONLY THE LATEST VALIDLY EXECUTED PROXY THAT YOU SUBMIT WILL BE COUNTED.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>IF YOU ARE A STREET-NAME HOLDER (I.E., IF YOUR
SHARES ARE HELD FOR YOU BY A CUSTODIAN BROKER OR BANK) AND IF YOU ALREADY HAVE PROVIDED YOUR BROKER OR BANK CUSTODIAN WITH VOTING INSTRUCTIONS
USING THE COMPANY&rsquo;S WHITE VOTING INSTRUCTION FORM OR VIA THE INTERNET, YOU MAY REVOKE YOUR PREVIOUSLY SUBMITTED VOTING INSTRUCTIONS
BY SIGNING AND SUBMITTING A LATER-DATED <U>GOLD</U> UNIVERSAL VOTING INSTRUCTION FORM USING THE POSTAGE-PAID ENVELOPE PROVIDED BY YOUR
CUSTODIAN BROKER OR BANK OR VIA THE INTERNET BY FOLLOWING THE INSTRUCTIONS PROVIDED BY YOUR CUSTODIAN BROKER OR BANK. IN THAT CASE, YOUR
CUSTODIAN BROKER OR BANK WILL SEEK TO GIVE EFFECT TO ONLY THE LATEST-DATED VOTING INSTRUCTIONS IT RECEIVES FROM YOU.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>HOLDERS OF SHARES AS OF THE RECORD DATE ARE URGED
TO SUBMIT A&nbsp;<U>GOLD</U>&nbsp;UNIVERSAL PROXY CARD EVEN IF YOUR SHARES WERE SOLD AFTER THE RECORD DATE.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>IF YOUR SHARES ARE HELD IN THE NAME OF A BROKERAGE
FIRM, BANK, BANK NOMINEE OR OTHER INSTITUTION ON THE RECORD DATE, ONLY THAT INSTITUTION CAN VOTE THOSE SHARES AND ONLY UPON RECEIPT OF
YOUR SPECIFIC INSTRUCTIONS. ACCORDINGLY, PLEASE PROVIDE YOUR BROKER OR BANK CUSTODIAN WITH VOTING INSTRUCTIONS BY SIGNING, DATING AND
RETURNING THE <U>GOLD</U> UNIVERSAL VOTING INSTRUCTION FORM USING THE ENCLOSED POSTAGE-PAID ENVELOPE OR VIA THE INTERNET BY FOLLOWING
THE INSTRUCTIONS PROVIDED BY YOUR CUSTODIAN BROKER OR BANK OR BY CONTACTING THE PERSON RESPONSIBLE FOR YOUR ACCOUNT AND INSTRUCTING THAT
PERSON TO SIGN AND RETURN ON YOUR BEHALF THE <U>GOLD</U>&nbsp;UNIVERSAL PROXY CARD AS SOON AS POSSIBLE.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If you have any questions or require any assistance
with your vote, please contact HKL &amp; Co., LLC, which is assisting us, at its address, telephone numbers or email address listed below.
This Proxy Statement is first being sent or given to stockholders on or about April 27, 2023.</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; background-color: white">&nbsp;</P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp; Thank you for your support,</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"></P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp; Icahn Capital LP</P>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; background-color: white"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt 3in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 100%; border: black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 12pt; text-align: justify"><I>If you have any questions, require assistance
    in voting your <B><U>GOLD</U></B> universal proxy card or need additional copies of the Participants&rsquo; proxy materials, please contact
    HKL &amp; Co., LLC at its address, telephone numbers or email address listed below. </I></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>HKL &amp; Co., LLC</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>3 Columbus Circle, 15<SUP>th</SUP> Floor</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>New York, NY 10019</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Banks and Brokerage Firms Please Call Collect: +1
    (212) 468-5380 </B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: center"><B>All Others Call Toll-Free: +1 (800) 257-3995<BR>
    Email: ILMN@hklco.com</B></P></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 10pt"><B>&nbsp;</B></FONT><B>2023
ANNUAL MEETING OF STOCKHOLDERS </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>OF</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>ILLUMINA, INC. </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">5200 Illumina Way</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">San Diego, CA 92122</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>__________________________</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>PROXY STATEMENT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>OF</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>ICAHN CAPITAL LP </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>_________________________</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B><U>PLEASE SIGN, DATE AND MAIL THE ENCLOSED GOLD
UNIVERSAL PROXY CARD TODAY</U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">Icahn Partners
LP (&ldquo;<U>Icahn Partners</U>&rdquo;), Icahn Partners Master Fund LP (&ldquo;<U>Icahn Master</U>&rdquo;), Icahn Onshore LP (&ldquo;<U>Icahn
Onshore</U>&rdquo;), Icahn Offshore LP (&ldquo;<U>Icahn Offshore</U>&rdquo;), Icahn Capital LP (&ldquo;<U>Icahn Capital</U>&rdquo;), IPH
GP LLC (&ldquo;<U>IPH GP</U>&rdquo;), Icahn Enterprises Holdings L.P. (&ldquo;<U>Icahn Holdings</U>&rdquo;), </FONT>Icahn Enterprises
G.P. Inc. (&ldquo;<U>Icahn Enterprises GP</U>&rdquo;), Beckton Corp. (&ldquo;<U>Beckton</U>&rdquo;), Matsumura Fishworks LLC (&ldquo;<U>Matsumura</U>&rdquo;),
and <FONT STYLE="background-color: white">Carl C. Icahn (&ldquo;<U>Mr. Icahn</U>&rdquo;, together with Icahn Partners, Icahn Master, Icahn
Onshore, Icahn Offshore, Icahn Capital, IPH GP, Icahn Holdings, Icahn Enterprises GP, Beckton, and </FONT>Matsumura, <FONT STYLE="background-color: white">the
&ldquo;<U>Icahn Participants</U>&rdquo; or &ldquo;<U>we</U>&rdquo;), are stockholders of Illumina, Inc., a Delaware corporation (&ldquo;<U>Illumina</U>&rdquo;
or the &ldquo;<U>Company</U>&rdquo;). </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">We are writing
to you in connection with our solicitation of proxies for use at the 2023 Annual Meeting of Stockholders of the Company scheduled to be
held virtually on </FONT>May 25, 2023 at 10:00 a.m. (Pacific time), and <FONT STYLE="background-color: white">at any and all adjournments,
continuations or postponements thereof (the &ldquo;<U>Annual Meeting</U>&rdquo;).</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">As more fully
discussed in this Proxy Statement, </FONT>the terms of the Company&rsquo;s current directors will expire at the Annual Meeting. Under
the proxy rules, we may solicit proxies in support of the Icahn Nominees (as defined below). This would enable a stockholder who desires
to vote for up to a full complement of nine (9)&nbsp;director nominees to use the&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy card or,
if applicable, the <B><U>GOLD</U></B> voting instruction form to vote for the Icahn Nominees.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We have determined to nominate&nbsp;<B>Vincent J.
Intrieri</B>, <FONT STYLE="background-color: white"><B>Jesse A. Lynn</B>, and <B>Andrew J. Teno</B> (collectively, the &ldquo;<U>Icahn
Nominees</U>&rdquo; and, together with the Icahn Participants, the &ldquo;<U>Participants</U>&rdquo;), </FONT>and are seeking authority
to vote &ldquo;<B><U>FOR</U></B>&rdquo; the election of all of our nominees. As a result, should a stockholder so authorize us, on the&nbsp;<B><U>GOLD</U></B>&nbsp;universal
proxy card, we would cast votes &ldquo;<B><U>FOR</U></B>&rdquo; the Icahn Nominees.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>THIS PROXY SOLICITATION IS BEING MADE BY THE PARTICIPANTS
AND NOT ON BEHALF OF THE BOARD OF ILLUMINA.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Illumina has set the record date for determining stockholders
entitled to notice of and to vote at the Annual Meeting as April 3, 2023 (the &ldquo;<U>Record Date</U>&rdquo;). Stockholders of record
at the close of business on the Record Date will be entitled to vote at the Annual Meeting, so long as the shares of common stock, par
value $0.01 per share (the &ldquo;<U>Shares</U>&rdquo;), remain outstanding on the date of the Annual Meeting. At the close of business
on the Record Date, there were <FONT STYLE="background-color: white">158,032,030 </FONT>Shares <FONT STYLE="background-color: white">of
Illumina</FONT> outstanding and entitled to vote at the Annual Meeting according to the Company&rsquo;s proxy statement filed with the
Securities and Exchange Commission (the &ldquo;<U>SEC</U>&rdquo;) on April 20, 2023. The Shares are the only class of stock entitled to
vote at the Annual Meeting. As of the Record Date, the Icahn Participants beneficially own <FONT STYLE="background-color: white">in the
aggregate 2,198,853</FONT> Shares<FONT STYLE="background-color: white">, which represents approximately</FONT> 1.4% <FONT STYLE="background-color: white">of
the outstanding Shares of the Company </FONT>as further described on <U>Annex&nbsp;I</U>. We intend to vote our Shares &ldquo;<B><U>FOR</U>&rdquo;</B>
the election of the Icahn Nominees to the Board.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We urge you to sign, date and return the <B><U>GOLD</U></B>
universal proxy card or, if applicable, the <B><U>GOLD</U></B> voting instruction form to elect the Icahn Nominees to the Board.</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">This Proxy Statement and <B><U>GOLD</U></B> universal
proxy card are first being mailed or given to the Company&rsquo;s stockholders on or about April 27, 2023.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>IF YOU ARE A STOCKHOLDER OF RECORD AND ALREADY
HAVE VOTED USING THE COMPANY&rsquo;S WHITE PROXY CARD OR VIA THE INTERNET BY FOLLOWING THE INSTRUCTIONS PROVIDED TO YOU BY THE COMPANY,
YOU MAY REVOKE YOUR PREVIOUSLY SUBMITTED WHITE PROXY BY SIGNING AND RETURNING A LATER-DATED&nbsp;<U>GOLD</U> UNIVERSAL PROXY CARD USING
THE ENCLOSED POSTAGE-PAID ENVELOPE, OR BY DELIVERING A WRITTEN NOTICE OF REVOCATION TO THE COMPANY OR TO THE SECRETARY OF THE COMPANY.
ONLY THE LATEST VALIDLY EXECUTED PROXY THAT YOU SUBMIT WILL BE COUNTED.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>IF YOU ARE A STREET-NAME HOLDER (I.E., IF YOUR
SHARES ARE HELD FOR YOU BY A CUSTODIAN BROKER OR BANK) AND IF YOU ALREADY HAVE PROVIDED YOUR BROKER OR BANK CUSTODIAN WITH VOTING INSTRUCTIONS
USING THE COMPANY&rsquo;S WHITE VOTING INSTRUCTION FORM OR VIA THE INTERNET, YOU MAY REVOKE YOUR PREVIOUSLY SUBMITTED VOTING INSTRUCTIONS
BY SIGNING AND SUBMITTING A LATER-DATED <U>GOLD</U> UNIVERSAL VOTING INSTRUCTION FORM USING THE POSTAGE-PAID ENVELOPE PROVIDED BY YOUR
CUSTODIAN BROKER OR BANK OR VIA THE INTERNET BY FOLLOWING THE INSTRUCTIONS PROVIDED BY YOUR CUSTODIAN BROKER OR BANK. IN THAT CASE, YOUR
CUSTODIAN BROKER OR BANK WILL SEEK TO GIVE EFFECT TO ONLY THE LATEST-DATED VOTING INSTRUCTIONS IT RECEIVES FROM YOU.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>HOLDERS OF SHARES AS OF THE RECORD DATE ARE URGED
TO SUBMIT A&nbsp;<U>GOLD</U>&nbsp;UNIVERSAL PROXY CARD EVEN IF YOUR SHARES WERE SOLD AFTER THE RECORD DATE.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>For instructions on how to vote and other information
about the proxy materials, see the Questions and Answers section starting on page 30.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="text-transform: uppercase"><B>We urge
you to promptly sign, date and return your <U>GOLD</U> UNIVERSAL proxy card OR, IF APPLICABLE, YOUR <U>GOLD</U> VOTING INSTRUCTION FORM.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="text-transform: uppercase"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>If you have any questions or require any assistance
in voting your Shares, please contact our proxy solicitor, HKL &amp; Co., LLC: Banks and Brokerage Firms Please Call Collect: +1 (212)
468-5380; All Others Call Toll-Free: +1 (800) 257-3995; Email: ILMN@hklco.com.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>


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    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>IMPORTANT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>Your vote is important, no matter how few Shares
you own. The Participants urge you to sign, date, and return the enclosed <U>GOLD</U> universal proxy card or, if applicable, <U>GOLD</U>
voting instruction form today to elect the Icahn Nominees. </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in"><B>&nbsp;</B></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.75in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify">If your Shares are registered in your own name, please sign and date the enclosed <B><U>GOLD</U></B> universal
proxy card and return it to Icahn Capital LP, c/o <FONT STYLE="background-color: white">HKL &amp; Co., LLC</FONT>, 3 Columbus Circle,
15<SUP>th</SUP> Floor, New York, NY 10019, using the enclosed postage-paid envelope today.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 1in; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.75in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify">If your Shares are held by a bank, brokerage firm, dealer, trust company or other custodian, you are considered
the beneficial owner of the Shares, and these proxy materials, together with a <B><U>GOLD</U></B> voting instruction form, are being forwarded
to you by your broker or bank. As a beneficial owner, you must instruct your broker, trustee or other representative how to vote. Your
bank, broker, trustee or other custodian cannot vote your Shares on your behalf without your instructions. You can provide the needed
voting instructions to your custodian broker or bank by completing, signing and dating the enclosed <B><U>GOLD</U></B> voting instruction
form and returning that completed form to your custodian broker or bank using the enclosed postage-paid return envelope provided by your
custodian broker or bank.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 1in; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.75in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify">Depending upon your bank, broker, trustee or other representative, you also may be able to vote via the
Internet. Please refer to the enclosed voting instruction form for instructions on how to vote electronically. As noted above, you may
also vote by signing, dating and returning the enclosed <B><U>GOLD</U></B> voting instruction form using the enclosed postage-paid return
envelope.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>IF YOU ARE A STOCKHOLDER OF RECORD AND ALREADY
HAVE VOTED USING THE COMPANY&rsquo;S WHITE PROXY CARD OR VIA THE INTERNET BY FOLLOWING THE INSTRUCTIONS PROVIDED TO YOU BY THE COMPANY,
YOU MAY REVOKE YOUR PREVIOUSLY SUBMITTED WHITE PROXY BY SIGNING AND RETURNING A LATER-DATED&nbsp;<U>GOLD</U> UNIVERSAL PROXY CARD USING
THE ENCLOSED POSTAGE-PAID ENVELOPE, OR BY DELIVERING A WRITTEN NOTICE OF REVOCATION TO THE COMPANY OR TO THE SECRETARY OF THE COMPANY.
ONLY THE LATEST VALIDLY EXECUTED PROXY THAT YOU SUBMIT WILL BE COUNTED.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>IF YOU ARE A STREET-NAME HOLDER (I.E., IF YOUR
SHARES ARE HELD FOR YOU BY A CUSTODIAN BROKER OR BANK) AND IF YOU ALREADY HAVE PROVIDED YOUR BROKER OR BANK CUSTODIAN WITH VOTING INSTRUCTIONS
USING THE COMPANY&rsquo;S WHITE VOTING INSTRUCTION FORM OR VIA THE INTERNET, YOU MAY REVOKE YOUR PREVIOUSLY SUBMITTED VOTING INSTRUCTIONS
BY SIGNING AND SUBMITTING A LATER-DATED <U>GOLD</U> UNIVERSAL VOTING INSTRUCTION FORM USING THE POSTAGE-PAID ENVELOPE PROVIDED BY YOUR
CUSTODIAN BROKER OR BANK OR VIA THE INTERNET BY FOLLOWING THE INSTRUCTIONS PROVIDED BY YOUR CUSTODIAN BROKER OR BANK. IN THAT CASE, YOUR
CUSTODIAN BROKER OR BANK WILL SEEK TO GIVE EFFECT TO ONLY THE LATEST-DATED VOTING INSTRUCTIONS IT RECEIVES FROM YOU.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 100%; border: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 12pt; text-align: justify"><I>If you have any questions, require assistance
    in voting your <B><U>GOLD</U></B> universal proxy card or need additional copies of the Participants&rsquo; proxy materials, please contact
    <FONT STYLE="background-color: white">HKL &amp; Co., LLC</FONT> at its address, telephone numbers or email address listed below. </I></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="background-color: white"><B>HKL &amp;
    Co., LLC</B></FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>3 Columbus Circle, 15<SUP>th</SUP> Floor</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>New York, NY 10019</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Banks and Brokerage Firms Please Call Collect: +1
    (212) 468-5380 </B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: center"><FONT STYLE="font-size: 10pt"><B>All Others Call
    Toll-Free: +1 (800) 257-3995<BR>
    Email: </B></FONT><B>ILMN@hklco.com</B></P></TD></TR>
  </TABLE>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Background
of the Solicitation</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Mr. Icahn and his
representatives have tried to engage in meaningful discussions with the Company&rsquo;s management to address, among other things, Mr.
Icahn&rsquo;s concerns that the Company&rsquo;s incumbent Board and management have failed, and continue to fail, to take actions to maximize
value for the Company&rsquo;s stockholders, including, but not limited to, the actions taken by the Board and the Company&rsquo;s management
relating to the GRAIL, Inc. (&ldquo;<U>GRAIL</U>&rdquo;) transaction. During the past few months, Mr. Icahn and his representatives have
made numerous attempts to engage directly with the Company and its management regarding these concerns, but these attempts have been met
with resistance.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Mr. Icahn has reviewed
the Company&rsquo;s description of the past contacts between the Company and Mr. Icahn in the Company&rsquo;s preliminary proxy statement
filed with the SEC on March 30, 2023, as updated in the Company&rsquo;s definitive proxy statement filed with the SEC on April 20, 2023.
Mr. Icahn disagrees with the Company&rsquo;s characterization of the material events leading up to this proxy solicitation and believes
that the Company&rsquo;s characterization of such events is misleading. The following is a chronology of the material events, including
the key interactions and communications between the Icahn Participants and the Company, leading up to the filing of this Proxy Statement:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify"><FONT STYLE="background-color: white">On February
13, 2023, Matsumura, Icahn Partners and Icahn Master purchased an aggregate of 430,000 Shares in open market purchases for an aggregate
purchase price of approximately $89.74 million. In addition, between February 13, 2023 and March 9, 2023, Icahn Partners and Icahn Master
entered into forward contracts (the &ldquo;<U>Forwards</U>&rdquo;) relating to 1,768,853 Shares, at a forward price of $170.00 per share,
for an aggregate forward price of approximately $300.7&nbsp;million, plus a financing charge. The Forwards expire on February 13, 2026.
The forward price is subject to adjustment to account for any dividends or other distributions declared by the Company. </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify"><FONT STYLE="background-color: white">On February
16, 2023, Matsumura, Icahn Partners and Icahn Master delivered a letter to the corporate secretary of the Company requesting the form
of director questionnaire required to propose directors to be nominated under Illumina&rsquo;s Bylaws. </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify"><FONT STYLE="background-color: white">On February
20, 2023, Illumina provided the form of questionnaire by email.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify"><FONT STYLE="background-color: white">On February
23, 2023, Carl C. Icahn and the Company&rsquo;s CEO, </FONT>Francis A. deSouza, participated in a conference call. On the call, Mr. Icahn
expressed his concern regarding the actions taken by the Company&rsquo;s Board and indicated that the Icahn Participants would be nominating
three individuals for election as directors of the Company&rsquo;s 2023 Annual Meeting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify">Also, on February 23, 2023, Matsumura, in its
capacity as a record holder of Shares, emailed Illumina a formal notice of its intent to nominate each of Vincent J. Intrieri, <FONT STYLE="background-color: white">Jesse
A. Lynn, and Andrew J. Teno</FONT>, who we refer to as the Icahn Nominees, as d<FONT STYLE="background-color: white">irector candidates
at the Annual Meeting pursuant to the requirements set forth in the Bylaws (the &ldquo;<U>Nomination Notice</U>&rdquo;). Each of the Icahn
Nominees also provided a consent to being named as a director nominee in any proxy solicitation materials and to serve on the Board if
elected or appointed. A copy of the Nomination Notice was hand delivered to Illumina&rsquo;s executive offices on February 24, 2023.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white">On
February 24, 2023, Mr. </FONT>deSouza indicated to Mr. Icahn that he would discuss the Icahn Nominees with John W. Thompson, the Chairman
of the Company&rsquo;s board, and with the full board of directors of the Company.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white">Mr.
Icahn invited Messrs. deSouza and Thompson to his offices in Sunny Isles Beach, Florida on March 2, 2023, to further discuss Mr. Icahn&rsquo;s
concern about the Company&rsquo;s operations and its failure to take actions that were in the best interest of all of the Company&rsquo;s
stockholders. During that meeting, Messrs. deSouza and Thompson indicated that it would be preferable from the Company&rsquo;s perspective
to consider nominating a director that was handpicked by the existing Board and the Company&rsquo;s Nominating &amp; Corporate Governance
Committee (&ldquo;<U>Governance Committee</U>&rdquo;). Mr. Icahn rejected this idea as the Board has not demonstrated that it is making
decisions to maximize stockholder value and has not been accountable to its stockholders. Mr. Icahn further indicated that he specifically
nominated the Icahn Nominees because each of the Icahn Nominees has a track record of serving on public company boards and acting in the
best interests of all stockholders. </FONT>In addition, none of the Icahn Nominees have been responsible for incinerating $50 billion
of shareholder value (based on the decline in Illumina&rsquo;s stock price from $510.61 per share</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">on August 18, 2021,
the day that the GRAIL transaction was announced, as compared to the per share price of $194.01 on March 10, 2023, the trading day prior
to the Participants&rsquo; public announcement of its intent to nominate directors at the Annual Meeting, multiplied by 156.5 million
Shares outstanding, which reflects the 146.7 million Shares that were outstanding as of July 30, 2021, as disclosed by the Company in
its Quarterly Report on Form 10-Q for the period ended July 4, 2021, plus the 9.8 million Shares that were issued to GRAIL stockholders
on August 18, 2021, as consideration, as disclosed by the Company in its Current Report on Form 8-K filed with the SEC on August 18, 2021).
The Participants believe that ILMN&rsquo;s decrease in stock price is directly related to the decision of the Company&rsquo;s Board to
close the GRAIL transaction without the required regulatory approvals.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">Mr. Icahn also
asked during the meeting why the Company was pursuing the GRAIL transaction so maniacally, including closing the GRAIL deal over the explicit
prohibition of antitrust regulators. Chairman Thompson responded, &ldquo;Because I want to own it,&rdquo; and CEO deSouza agreed. </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">Mr. Icahn and
the other Participants do not understand why the incumbent directors are blinded by their obsession and will do anything in their pursuit
of GRAIL as reflected by the Board&rsquo;s actions in closing the GRAIL transaction over the explicit objections from regulators in both
the European Union and the U.S., the continued efforts by the Board to appeal the recent decision of the Federal Trade Commission that
would require Illumina to divest GRAIL, and the Board&rsquo;s decisions to continue to expend funds in connection with these legal challenges
despite the Company&rsquo;s declining stock price, which has resulted in the destruction of $50 billion of stockholder value.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">The parties
agreed that the discussions were to be kept confidential as they related to potential settlement discussions. However, the Company&rsquo;s
representatives subsequently violated that confidentiality agreement. As such, Mr. Icahn considers his obligations thereunder to be dissolved.
</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Following the meeting
in Mr. Icahn&rsquo;s offices, <FONT STYLE="background-color: white">Mr. </FONT>deSouza contacted Mr. Icahn to request that interviews
be scheduled between the Icahn Nominees and the Governance Committee. <FONT STYLE="background-color: white">Each of the Icahn Nominees
met with members of the Governance Committee on March 7 or March 8, 2023. </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white">On
March 8, 2023 &ndash; the same day that the Company interviewed the Icahn Nominees and the Company&rsquo;s Board purportedly &ldquo;deliberated&rdquo;
regarding the qualifications of such nominees and determined not to discuss a settlement with Mr. Icahn &ndash; Messrs. deSouza and Thompson
had a conference call with Mr. Icahn to inform him that the Board would not be nominating the three Icahn Nominees.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white">Mr.
Icahn firmly believes that the interviews of the Icahn Nominees were merely perfunctory and that the Company did not consider the actual
qualifications, skills and contributions that could be made by each of the Icahn Nominees to the Company&rsquo;s Board. The interviews
that were conducted did not include all of the members of the Governance Committee and the Company did not contact any of the references
that were provided by the Nominees. In addition, the Company decided, and communicated to the Icahn Nominees, that it would not nominate
any of the Icahn Nominees within hours of actually conducting the interviews, which does not suggest that the Governance Committee diligently
reviewed, considered and evaluated the Icahn Nominees. Instead, the Company inappropriately focused on the fact that Mr. Icahn has a relationship
with each of the Icahn Nominees (an obvious fact disclosed in the Nomination Notice and which Mr. Icahn did not attempt to conceal). As
Mr. Icahn is putting forth these individuals as nominees to the Company&rsquo;s Board, one would expect that he would know these individuals!</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white">On
March 9, 2023, Mr. deSouza contacted Mr. Icahn and noted that the Company might consider a settlement involving one Icahn nominee and
an independent candidate that had been handpicked by the Company. Mr. Icahn reiterated his view that the Company&rsquo;s stockholders
deserve directors that are looking out for their best interests and that he did not believe one director would be sufficient, given the
entrenched nature of the Company&rsquo;s Board. Mr. Icahn said that he might consider accepting two of the Icahn Nominees and one individual
that was not affiliated with the Company&rsquo;s Board or management team if Mr. deSouza was willing to get back to him about that by
March 13, 2023. Mr. deSouza never contacted Mr. Icahn to discuss that potential settlement.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white">On
March 13, 2023, Mr. Icahn issued an open letter to the Company&rsquo;s stockholders in which Mr. Icahn expressed concern over the decisions
that the Company&rsquo;s Board has made that have led to a significant loss of stockholder value. Mr. Icahn indicated he believes that
the Icahn Nominees will provide a &ldquo;badly needed dose of sanity to Illumina&rsquo;s boardroom&rdquo; and that stockholder </FONT>representatives
are &ldquo;needed on Illumina&rsquo;s board to attempt to put an end to this</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">insanity now before
the reckless decision making escalates into a no-return situation.&rdquo; In his letter, Mr. Icahn noted that the Company&rsquo;s Board
has continued to make &ldquo;reckless decisions&rdquo; with respect to the GRAIL transaction by closing the transaction before the European
Commission had completed its regulatory review of the transaction.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On March 13, 2023,
the Company responded to Mr. Icahn&rsquo;s letter and indicated that the Company does not support the Icahn Nominees.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On March 15, 2023,
Mr. Icahn issued an open letter to the Company&rsquo;s stockholders noting that the investment &ldquo;thesis is simple. The decision by
Illumina&rsquo;s board of directors to close the company&rsquo;s acquisition of GRAIL over the explicit prohibition from European Commission
regulators exposed Illumina to terrible risks, shows a lack of common sense AND, most disturbingly, destroyed $50 billion of shareholder
value.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On March 20, 2023,
the Company issued a press release where it responded to Mr. Icahn&rsquo;s letter with the following conclusory statements: <FONT STYLE="background-color: white">Illumina&rsquo;s
plan will maximize shareholder value; Illumina is engaged with regulators to define GRAIL&rsquo;s path forward as expeditiously as possible;
and Icahn&rsquo;s director nominees do not add value to the Company&rsquo;s Board and will damage Illumina&rsquo;s core business.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On March 24, 2023,
the Icahn Participants provided notice to the Company pursuant to Rule 14a-19(b)(1) of the Exchange Act that the Icahn Participants intend
to solicit proxies for the Icahn Nominees for the election to the Board at the Annual Meeting and that the Icahn Participants intend to
solicit proxies from holders of the outstanding capital stock of the Company that represents at least 67% of the voting power of the shares
of capital stock entitled to vote on the election of directors in support of the Icahn Nominees.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0; background-color: white"><FONT STYLE="background-color: white">Also,
on March 24, 2023, Mr. Icahn issued an open letter to Illumina&rsquo;s stockholders referring the Company&rsquo;s stockholders to a suspicious
insurance matters agreement (the &ldquo;<U>Insurance Agreement</U>&rdquo;) that was filed, without explanation, as an exhibit to a Form
10-Q filing by the Company, which provides a fourth layer of liability protection to Illumina&rsquo;s directors (beyond the customary
indemnification provided by the Company&rsquo;s certificate of incorporation and bylaws, the customary coverage provided by the Company&rsquo;s
existing directors and officers insurance policy and the customary coverage provided by the individual indemnification agreements entered
into by the Company and each director) relating specifically to the controversial GRAIL transaction. The Insurance Agreement is &ldquo;effective&rdquo;
as of August 18, 2021 but was not filed by the Company until November 5, 2021. The Company did file a Form 8-K on August 18, 2021, announcing
the closing of the GRAIL transaction and included several other agreements as exhibits to that Form 8-K filing. This begs the question
as to why the Company could file the other agreements that were required to be filed in that Form 8-K but specifically chose not to file
or mention the existence of the Insurance Agreement even though it was purportedly effective as of the same day &ndash; August 18, 2021.
We do not know why the Company chose not to file the Insurance Agreement when it filed its Form 8-K and, as a result, we are left to wonder
whether the Insurance Agreement was signed either immediately prior to the closing of the GRAIL transaction or perhaps after the fact
and backdated (we don&rsquo;t know and the Company won&rsquo;t say). </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0; background-color: white"><FONT STYLE="background-color: white">The
Company&rsquo;s failure to timely file the Insurance Agreement strongly suggests that the Company was trying to avoid drawing attention
to the agreement. The Participants believe that the Insurance Agreement is highly unusual and should have been promptly disclosed by the
Company, particularly since the Company disclosed all of the other material arrangements relating to the GRAIL transaction on August 18,
2021 but chose to wait until November 5, 2021 to disclose the Insurance Agreement. The Insurance Agreement purports to absolve the directors
from &ldquo;any and all claims against any of them arising out of or relating to&rdquo; the GRAIL acquisition including &ldquo;any determinations
or decisions in connection with regulatory approvals, rulings or other actions&hellip;.&rdquo; We question why extra indemnification is
necessary for the members of the Company&rsquo;s Board for decisions in connection with regulatory approvals (as the directors were already
indemnified in connection with their service). We believe the execution of this highly suspicious and unprecedented agreement, the fact
that it was not disclosed in a timely fashion, and the fact that, when it was finally disclosed, there was a clear attempt to bury it
by filing the form of agreement as an exhibit to a routine SEC filing without any narrative explanation whatsoever, represents a NEW LOW
IN CORPORATE GOVERNANCE. Illumina and its Board were well aware that closing the acquisition of GRAIL over the objections of the European
regulators could adversely impact Illumina&rsquo;s business and in the same Form 8-K where it announced the closing of the GRAIL transaction,
Illumina also disclosed that &ldquo;[a]s a result of Illumina&rsquo;s decision to proceed with the completion of the [GRAIL] Acquisition
during the pendency of the European Commission&rsquo;s review, the European Commission</FONT></P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0; background-color: white">will
likely seek to impose a fine on Illumina pursuant to Article 14(2)(b) of the EU Merger Regulation of up to 10% of Illumina&rsquo;s consolidated
annual turnover. In addition, the European Commission, the FTC and/or other governmental or regulatory authorities may seek to impose
other fines, penalties, remedies or restrictions.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0; background-color: white"><FONT STYLE="background-color: white">Evercore
ISI agreed with us, stating on March 24, 2023: &ldquo;We don&rsquo;t generally look at Exhibits to 10-Q filings&hellip;we can see why
Mr. Icahn claims the filing was &lsquo;buried&rsquo;&hellip;The timing of the Agreement (day the Grail deal closed) and language around
protection against personal liability related to acquisition hints that the Board of Directors knew there were risks to the transaction.&rdquo;
</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white">On
March 25, 2023, the Company issued a materially misleading press release stating that &ldquo;Directors and Officers (D&amp;O) insurance
and corporate indemnification are standard for Delaware companies.&rdquo; The Company purposely obfuscates the point &ndash; nobody is
arguing that the directors should not have insurance and indemnification agreements, <U>but why do the Company&rsquo;s directors need
another layer of coverage specific to the GRAIL acquisition and what exposures did the Company believe this new Insurance Agreement was
covering that was not already covered?</U> Moreover, why did the Company fail to provide any disclosure regarding this Insurance Agreement
until well after the GRAIL acquisition closed? The Company did not just increase its D&amp;O coverage &ndash; it provided yet another
contract providing coverage to its directors immediately prior to when its directors were making decisions about the GRAIL transaction
(or perhaps the Insurance Agreement was executed after the fact and backdated &ndash; it is impossible to tell and the Company has thus
far dubiously refused to provide any explanation). The Company again stated that its Board &ldquo;acts in the best interests of its shareholders&rdquo;
and that &ldquo;Mr. Icahn has no ability to accelerate the legal and regulatory processes and neither do his nominees.</FONT>&rdquo; The
Company&rsquo;s conclusory statements that its directors act in the best interest of its shareholders do not explain how the Board came
to the conclusion that it should ignore all precedent and proceed with the GRAIL acquisition in the absence of the required regulatory
approvals. Mr. Icahn believes that by announcing the intention to immediately refocus on its core business and withdraw its many futile
and expensive appeals (the only efficacy of which is to further infuriate regulators and customers), Illumina will able to separate GRAIL
much more quickly, and under way more advantageous terms, than will ever be possible if the Company continues barreling down the value-destructive
path that CEO Francis deSouza and Chairman John Thompson have concocted.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On March 30, 2023,
the Company filed its preliminary proxy statement with the SEC, which, among other things, grossly mischaracterized the prior discussions
that had taken place between Mr. Icahn and Messrs. Thompson and deSouza. Despite the parties&rsquo; agreement to maintain the confidentiality
of the settlement negotiations, the Company reported in its preliminary proxy that it would have agreed to a settlement involving one
director, but that Mr. Icahn demanded two or three board seats.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On March 30, 2023,
Bloomberg reported Mr. Icahn as stating, <FONT STYLE="background-color: white">&ldquo;Today Illumina&rsquo;s representatives have broken
their word and gone public and taken out of context certain things that were supposedly said during these discussions.&rdquo;</FONT> Bloomberg
also reported that the Company&rsquo;s market value has fallen to approximately $36 billion from approximately $75 billion in August 2021,
the month that the Company closed its acquisition of GRAIL.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On March 30, 2023,
Mr. Icahn issued an open letter to the Company&rsquo;s stockholders regarding his concerns relating to the credibility of Mr. deSouza
and his exerting control of the Company&rsquo;s existing Board, which concluded: &ldquo;Should the board of directors of Illumina be blindly
following an individual who has violated court orders and fiduciary duties? If one of the most important regulatory bodies in the United
States believes that Mr. deSouza is an untrustworthy character, and a respected judge has found his &ldquo;credibility suspect&rdquo;
and also found his testimony &ldquo;not to be trusted&rdquo;, how can shareholders and this board trust him to execute the strategy of
our company? Based on the above facts, and after researching Mr. deSouza&rsquo;s actions over the past years, including the fact that
he destroyed $50 billion of shareholder value, and speaking with numerous individuals and shareholders, we believe it is unconscionable
that the board of directors still entrusts him with running our potentially great company.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On April 3, 2023,
Mr. Icahn issued an open letter to the Company&rsquo;s stockholders questioning the directors &ldquo;infinite wisdom&rdquo; in deciding
to pay the Company&rsquo;s CEO an astonishing $27 million in 2022, which was an 87% increase to his compensation for 2021.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On April 3, 2023,
the Federal Trade Commission (the &ldquo;<U>FTC</U>&rdquo;) issued an opinion and order requiring Illumina to divest GRAIL, which makes
a multi-cancer early detection (&ldquo;<U>MCED</U>&rdquo;) test, as it found that the transaction would diminish</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">innovation in the
U.S. market for life-saving cancer tests while increasing prices and decreasing choice and quality of tests and noted in its press release
that &ldquo;[t]his is extremely concerning given the importance of swiftly developing effective and affordable tools to detect cancer
early.&rdquo; The FTC&rsquo;s press release notes that &ldquo;[r]eal world evidence of Illumina&rsquo;s past behavior reinforces the [FTC&rsquo;s]
antitrust concerns. For instance, Illumina gave GRAIL special pricing and other benefits while it was wholly owned by Illumina.&rdquo;
In addition, the FTC in its opinion and order questioned Illumina&rsquo;s entire justification for acquiring GRAIL in the first place,
stating: &ldquo;In sum, Respondents have failed to substantiate that this Acquisition is likely to yield merger-specific acceleration
efficiencies that save lives. Rather than rely on Respondents&rsquo; <U>self-serving and ultimately vague and unsupported projections
of acceleration</U>, we believe the course that Congress clearly enunciated in the antitrust laws is to let competition spur innovation
among MCED test providers and thereby save lives.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0; background-color: white">On
April 5, 2023, an article appearing in Bloomberg stated: &ldquo;<U>However you slice it, spinning something off and buying it back a few
years later for much more is a bad look</U>. That Illumina agreed to do so on the heels of having its proposed takeover of Pacific Biosciences
blocked, resulting in the payment of a $98 million breakup fee, made it all the worse. Having agreed to the transaction, deSouza then
set his company on a collision course with regulators, announcing in August 2021 that Illumina would close the deal despite a review by
European antitrust authorities. (The company last year set aside $453 million for a potential EU fine for completing the merger without
approval.) Shareholders haven&rsquo;t enjoyed the ride. Illumina&rsquo;s shares, which traded at $525 that month, have lost more than
half of their value, wiping about $40 billion from the company&rsquo;s market capitalization. When the FTC followed suit, some CEOs would
have folded. Not deSouza. He has pulled his shareholders into a yearslong fight, which was extended on Monday, and he failed to telegraph
either the risks or duration. It has been an expensive undertaking. Illumina, still unable to integrate a deal it ostensibly closed on
in 2021, is spending about $700 million a year to keep it running in limbo. If it is forced to divest Grail, there is no obvious path
where it doesn&rsquo;t take a loss on the billions it paid for it.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On April 5, 2023,
Mr. Icahn issued an open letter to the Company&rsquo;s stockholders expressing concern that the Company&rsquo;s Board and CEO have &ldquo;decided
to continue their long history of appealing (and appealing again) in the hope of one day, at great expense, winning an almost impossible
battle&rdquo; against the FTC and EU regulators&rsquo; decision to block the GRAIL transaction. Mr. Icahn and the other Participants do
not see any reason for Illumina to continue its losing battle with the U.S. and EU antitrust and competition regulators regarding its
obsessive desire to acquire GRAIL.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0; background-color: white">On
April 6, 2023, an article appearing in the National Law Journal stated: &ldquo;The saga of the GRAIL reacquisition has been bad practice
all around, starting with Illumina, which has squandered billions of dollars on a risky transaction that could cost it hundreds of millions
more. In 2021, Illumina took a $3.9 billion impairment charge, implying a value of roughly half the acquisition price one year later.
Illumina has also been forced to fund GRAIL operationally, which is reportedly costing Illumina $800 million annually. In addition, by
defying the EC&rsquo;s hold-separate rule, Illumina could face more than $450 million in fines&hellip;Ordinarily a platform monopolist
will understand the benefits of internalizing complementary efficiencies, meaning that it serves the platform operator&rsquo;s interest
to promote and maintain fully competitive markets for complementary products. If the platform operator doesn&rsquo;t do so, the company
will fail to internalize the benefits of the complementary markets. <U>Economic research recognizes several situations in which platform
operators exert anticompetitive control over complementary markets against their own interests. One of them is corporate incompetence.
This appears to the crux of the FTC&rsquo;s case against Illumina, i.e., that management is not sophisticated enough to maintain efficient
and open access to its platform to rival MCED testing firms</U>&hellip;[T]he Commission clearly believes that Illumina management intends
to maximize profits by acquiring GRAIL and eliminating competition in the MCED testing market. But, if so, Illumina&rsquo;s management
would be ignoring the fact that the company will maximize profits (and, thus, shareholder value) by optimizing modularity of its platform
through fully competitive complementary markets, not by excluding rivals from them. This is fodder for dissenting shareholders: Had Illumina&rsquo;s
management understood the true economic power of their platform, they would never have sought to reacquire GRAIL in the first place, and,
upon doing so, would never have given the FTC the idea that they cannot be trusted to be good stewards of a competitive complementary
market for Illumina-based MCED testing.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Also, on April 6,
2023, GenEdge News published an interview with Conor McNamara, CFA, equity research analyst with RBC Capital Markets, which contained
the following:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; text-indent: 0.5in; margin-right: 0; margin-left: 0; background-color: white">&ldquo;GEN
Edge: Are investors really clamoring for change, given things like GRAIL?</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0.5in; background-color: white">McNamara:
I think the easiest way to tell is what happened to the stock price, and the stock price did sell off when they announced they were buying
GRAIL. <U>When Icahn stepped in to say he was going to push for GRAIL to be gone, you saw the stock price respond positively. I think
that&rsquo;s your best indicator that there are a lot of shareholders that think that the company should focus on its base business and
not GRAIL</U>.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On April 7, 2023,
the Company filed an amendment to its preliminary proxy statement with the SEC.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On April 10, 2023,
the Participants issued a presentation regarding Illumina.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On April 11, 2023,
the Participants filed this preliminary proxy statement with the SEC.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On April 20, 2023,
the Company filed its definitive proxy statement with the SEC, in which the Company cryptically disclosed for the first time that its
Governance Committee expects that &ldquo;it will propose the appointment of two new directors after the 2023 annual meeting&rdquo;. In
typical Illumina fashion, this extremely material information was not highlighted in a Form 8-K filing but was included on page 14 of
the Company&rsquo;s proxy statement. We suspect that the authors of the Company&rsquo;s proxy statement hoped that this news, which clearly
demonstrates a blatant attempt to disenfranchise Illumina stockholders by packing the Board with two additional handpicked directors,
would go unnoticed until after the election. We question why the Company elected not to add these two individuals to the Company&rsquo;s
slate so that the Company&rsquo;s stockholders would have an opportunity to choose for themselves at the Annual Meeting whether they wished
to have these unnamed individuals added to the Board.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On April 21, 2023,
the Participants filed this revised preliminary proxy statement with the SEC.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On April 24, 2023,
Mr. Icahn issued an open letter to the Company&rsquo;s stockholders expressing concerns as to why the Company&rsquo;s Governance Committee
intends to appoint two new directors after the Annual Meeting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">On April 27, 2023,
the Participants filed this definitive proxy statement with the SEC.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Except as otherwise
noted herein, the information in this Proxy Statement concerning the Company has been taken from or is based upon documents and records
on file with the SEC and other publicly available information.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify"><FONT STYLE="background-color: white"><B>WE
STRONGLY RECOMMEND THAT YOU VOTE&nbsp;&ldquo;<U>FOR</U>&rdquo;&nbsp;THE ELECTION OF EACH OF THE ICAHN NOMINEES.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center"><B>&nbsp;</B></P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>REASONS
FOR OUR SOLICITATION</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">We are soliciting
your support to elect the Icahn Nominees at the Annual Meeting because we believe that an immediate change in the leadership of Illumina
is needed. We believe that at least three stockholder representatives are needed on Illumina&rsquo;s Board to ensure that the Board is
accountable to its stockholders. The Board&rsquo;s reckless decision to close the GRAIL transaction over the objections of European regulators
has created a situation where Illumina is forced to pay for the on-going operations of GRAIL without the ability to integrate GRAIL into
Illumina&rsquo;s operations and therefore cannot realize any synergies or cost savings from the acquisition. In addition, the Board has
painted Illumina into a corner such that the Company is now in the untenable position where it may have to pay a significant fine as a
result of closing the GRAIL acquisition and pay up to $1.75 billion in taxes if the Company is forced to divest GRAIL at the same price
for which the Board agreed to purchase GRAIL.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">We believe that Illumina
will continue its current value destroying behavior unless representatives of the stockholders are seated on the Board. We believe that
Illumina is facing a crisis and the stockholders must act to prevent further value destruction.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Our nominees are immensely
qualified, and we believe that their expertise would help to realign Illumina&rsquo;s operating and capital decisions and overall strategy
&ndash; which must focus on decision making that is in the best interests of the Company&rsquo;s stockholders. We expect that our nominees,
if elected, would offer a fresh perspective, and would help to implement a new strategic direction for the Company, including reviewing
potential alternatives relating to the GRAIL acquisition. It is essential that Illumina extricate itself immediately from the dire position
it might well sink into financially if it remains on this perilous course.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">In our view, the Board
needs to be reconstituted with highly qualified Board members to drive long-term value. We are confident that we have assembled the right
people who will fully explore all available strategies to assist in creating substantial value for the benefit of all Company stockholders.
We strongly believe our slate of directors brings sophisticated expertise to oversee the Company. The Icahn Nominees have extensive experience
in operations, finance, legal, regulatory matters, transactions, strategy, leadership and corporate governance. See the section titled
&ldquo;<I>Matters to be Considered at the Annual Meeting&mdash;Proposal 1: Election of the Icahn Nominees&mdash;Biographical Information
Regarding the Icahn Nominees</I>&rdquo; for a description of our nominees&rsquo; qualifications. Each of the Icahn Nominees recognizes
that as a member of the Board each of them will owe fiduciary duties to all of the Company&rsquo;s stockholders.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Stockholders are permitted
to vote for any combination (up to nine (9) total) of the Icahn Nominees and the Company&rsquo;s nominees on the&nbsp;<B><U>GOLD</U></B>&nbsp;universal
proxy card. However, if stockholders choose to vote for any of the Company&rsquo;s nominees, we recommend that stockholders &ldquo;<B><U>WITHHOLD</U></B>&rdquo;
on Francis A. deSouza, Robert S. Epstein, and John W. Thompson, who we refer to as the &ldquo;<U>Opposed Company Nominees</U>.&rdquo;
The Company&rsquo;s other six (6) nominees (Frances Arnold, Caroline D. Dorsa, Scott Gottlieb, Gary S. Guthart, Philip W. Schiller and
Susan E. Siegel) are referred to hereafter as the &ldquo;<U>Acceptable Company Nominees</U>.&rdquo; We make no recommendation on the Acceptable
Company Nominees.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">The Participants recommend
that stockholders &ldquo;<B><U>WITHHOLD</U></B>&rdquo; on:</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 12pt; margin-bottom: 0; background-color: white"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in"><B>(1)</B></TD><TD STYLE="text-align: justify"><B>Francis A. deSouza, as he is the CEO of the Company and led the efforts to pursue the ill-fated GRAIL
transaction over the explicit objections of European and U.S. regulators when he was aware that the consequences could result in material
fines and expenses as well as the forced divestiture of GRAIL;</B></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 12pt; margin-bottom: 0; background-color: white"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in"><B>(2)</B></TD><TD STYLE="text-align: justify"><B>Robert S. Epstein, as he is the Chairman of the Company&rsquo;s Governance Committee and we believe
that the Company has a terrible track record with respect to corporate governance matters, as evidenced by the Company&rsquo;s continued
efforts to pursue closing the GRAIL transaction over the objection of European and U.S. regulators when the Company was well aware of
the adverse consequences that could result, the long-term relationship between Mr. Epstein, who has served on the Board since 2012, and
Mr. deSouza, who has served on the Board since 2013 and as CEO since 2016, which we believe has impacted Mr. Epstein&rsquo;s ability to
facilitate good corporate governance, and the fact that Mr. Epstein has allowed Mr. Thompson to continue to serve on the</B></TD></TR></TABLE>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0 0.75in; text-align: justify; background-color: white"><B>Board despite
concerns raised regarding Mr. Thompson&rsquo;s behavior in his service on another board, as more fully discussed below; and</B></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 12pt; margin-bottom: 0; background-color: white"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in"><B>(3)</B></TD><TD STYLE="text-align: justify"><B>John W. Thompson, as he is the Chairman of the Board and has failed to hold Illumina&rsquo;s CEO accountable
and has exhibited questionable behavior in connection with his service on another board, which included allegations relating to conflicts
of interests, which would have disqualified him from being &ldquo;independent&rdquo; when he was serving as the lead independent director,
and his failure to appropriately oversee an investigation relating to sexual harassment allegations. Specifically, Glass Lewis recommended
that stockholders of Microsoft Corporation vote <U>against</U> the re-election of Mr. Thompson, who was then serving as Microsoft&rsquo;s
lead independent director, on two separate occasions &ndash; once in 2013 and once in 2021 &ndash; due to concerns relating to his behavior,
including potential conflicts of interest and oversight of investigations into sexual harassment allegations.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">We refer to these
individuals as the &ldquo;Opposed Company Nominees.&rdquo; We believe that these individuals, who were supposed to act as fiduciaries
to all of the Company&rsquo;s stockholders, have failed to consider all of the risks associated with GRAIL transaction and have relentless
pursued the acquisition over the clear objections of the U.S. and EU regulators. <B>These actions have destroyed $50 billion of stockholder
value. </B>Accordingly, we believe that the Company&rsquo;s stockholders must hold the Company&rsquo;s leadership accountable.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white"><B>WE
STRONGLY RECOMMEND A VOTE&nbsp;&ldquo;<U>FOR</U>&rdquo;&nbsp;THE ELECTION OF THE ICAHN NOMINEES.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">If you have any questions
or require any assistance with voting your Shares, please contact our proxy solicitor, <FONT STYLE="background-color: white">HKL &amp;
Co., LLC</FONT>: Banks and Brokerage Firms Please Call Collect: +1 (212) 468-5380; All Others Call Toll-Free: +1 (800) 257-3995; Email:
ILMN@hklco.com.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="background-color: white"><B>MATTERS TO
BE CONSIDERED AT THE ANNUAL MEETING</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="background-color: white"><B>Proposal 1:
Election of the Icahn Nominees</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: justify; background-color: white">The Board currently
consists of 9 directors. Directors hold office until the Company&rsquo;s next annual meeting following their election or until their successors
are elected and duly qualified. Accordingly, on February 23, 2023, the Icahn Participants gave notice to the Company of our intention
to nominate the three (3) Icahn Nominees to serve as directors of the Company.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">We have determined
to nominate <FONT STYLE="background-color: white"><B>Vincent J. Intrieri, Jesse A. Lynn, </B>and <B>Andrew J. Teno</B></FONT>. As a result,
should a stockholder so authorize us, on the&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy card, we would cast votes &ldquo;<B><U>FOR</U></B>&rdquo;
all of the Icahn Nominees.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Each of the Icahn
Nominees has consented to being named a nominee in this Proxy Statement and has confirmed his willingness to serve on the Board if elected.
The Icahn Participants intend to vote all of their Shares &ldquo;<B><U>FOR</U></B>&rdquo; each of the Icahn Nominees and to &ldquo;<B><U>WITHHOLD</U></B>&rdquo;
on each of the Opposed Company Nominees and each of the Acceptable Company Nominees. If each of the Icahn Nominees are elected, they will
represent three out of nine (9) members of the Board. There can be no assurance that the Icahn Nominees will be able to implement the
actions that the Participants believe are necessary to enhance stockholder value.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Stockholders are permitted
to vote for any combination (up to nine (9) total) of the Icahn Nominees and the Company&rsquo;s nominees on the&nbsp;<B><U>GOLD</U></B>&nbsp;universal
proxy card. However, if stockholders choose to vote for any of the Company&rsquo;s nominees, we recommend that stockholders &ldquo;<B><U>WITHHOLD</U></B>&rdquo;
on Francis A. deSouza, Robert S. Epstein, and John W. Thompson, which we refer to as the &ldquo;<U>Opposed Company Nominees</U>.&rdquo;
The Company&rsquo;s other six (6) nominees (Frances Arnold, Caroline D. Dorsa, Scott Gottlieb, Gary S. Guthart, Philip W. Schiller and
Susan E. Siegel) are referred to hereafter as the &ldquo;<U>Acceptable Company Nominees</U>.&rdquo; We make no recommendation on the Acceptable
Company Nominees. We believe the best opportunity for the Icahn Nominees to be elected will arise if stockholders vote &ldquo;<B><U>FOR</U></B>&rdquo;
each of the Icahn Nominees and to &ldquo;<B><U>WITHHOLD</U></B>&rdquo; on or not vote &ldquo;for&rdquo; the Opposed Company Nominees on
the <B><U>GOLD</U></B> universal proxy card.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white"><I>Biographical
Information Regarding the Icahn Nominees</I></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">The following
information concerning the age, principal occupation and business experience during the last five years, and current public directorships
of each of the Icahn Nominees has been furnished to the Participants by each of the Icahn Nominees. </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0; background-color: white"><FONT STYLE="background-color: white"><B>Vincent
J. Intrieri</B>, age 66, </FONT>is the Founder and CEO of VDA Capital Management LLC, a private investment fund founded in January 2017.
Mr. Intrieri was previously employed by Carl C. Icahn-related entities in various investment-related capacities from 1998 to 2016. From
2008 to 2016, Mr. Intrieri served as Senior Managing Director of Icahn Capital LP, the entity through which Carl C. Icahn manages private
investment funds. In addition, from 2004 to 2016, Mr. Intrieri was a Senior Managing Director of Icahn Onshore LP, the general partner
of Icahn Partners LP, and Icahn Offshore LP, the general partner of Icahn Partners Master Fund LP, entities through which Mr. Icahn invests
in securities. Mr. Intrieri has served as a director of: Transocean Ltd. (NYSE: RIG) since 2014; and Hertz Global Holdings, Inc. (Nasdaq:
HTZ) since 2014. Mr. Intrieri graduated, with Distinction, from The Pennsylvania State University (Erie Campus) with a B.S. in Accounting
in 1984. Mr. Intrieri was a certified public accountant. Mr. Intrieri&rsquo;s&nbsp;<FONT STYLE="background-color: white">business address
is&nbsp;</FONT>1100 Biscayne Blvd., Unit 2001, Miami, Florida 33132. Mr. Intrieri does not own, and has not owned during the past two
years, directly or indirectly, beneficially or of record, any class of securities of the Company, including the Shares.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0.5in 5pt; text-align: justify; background-color: white"><I>Director
Qualifications: Mr. Intrieri is well qualified to serve on the Board due to his significant experience and expertise in finance and accounting,
international operations, strategy and public company governance.&nbsp;</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>Jesse A. Lynn</B>, age 53, has been General Counsel
of Icahn Enterprises L.P. (NASDAQ: IEP), a diversified holding company engaged in a variety of businesses, including investment, energy,
automotive, food packaging, real estate, home fashion and pharma, since 2014. Mr. Lynn has also served as Chief Operating Officer of Icahn
Capital LP, the</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">entity through which Carl C. Icahn manages investment
funds, since April 2021. From 2004 to 2014, Mr. Lynn was Assistant General Counsel of Icahn Enterprises. Prior to joining Icahn Enterprises,
Mr. Lynn worked as an associate in the New York office of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. in its business and finance
department from 2000 until 2004. From 1996 to 2000, Mr. Lynn was an associate in the corporate group at Gordon Altman Bukowski Weitzen
Shalov &amp; Wein. Mr. Lynn has been a director of:&nbsp;<FONT STYLE="background-color: #FEFEFE">Crown Holdings Inc. (NYSE: CCK), a global
supplier of packaging products, since December 2022;&nbsp;</FONT>Xerox Holdings Corporation (NASDAQ: XRX), a provider of print and digital
document products and services, since November 2021; FirstEnergy Corp. (NYSE: FE), an electric utility, since March 2021; and Conduent
Incorporated (NASDAQ: CNDT), a provider of business process outsourcing services, since April 2019. Mr. Lynn was previously a director
of: Cloudera, Inc. (NASDAQ: CLDR),&nbsp;<FONT STYLE="background-color: white">a provider of enterprise data cloud</FONT>&nbsp;services<FONT STYLE="background-color: white">,
from August 2019 through its sale to CD&amp;R and KKR in October 2021</FONT>; Herbalife Nutrition Ltd. (NYSE: HLF), a nutrition company,
from April 2014 to January 2021; and The Manitowoc Company, Inc. (NYSE: MTW), a capital goods manufacturer, from April 2015 to February
2018. Carl C. Icahn has or previously had non-controlling interests in each of Crown, Xerox, FirstEnergy, Conduent, Cloudera, Herbalife
and Manitowoc through the ownership of securities. Mr. Lynn received a B.A. from the University of Michigan in 1992 and a J.D. from the
Boston University School of Law in 1996. Mr. Lynn&rsquo;s&nbsp;<FONT STYLE="background-color: white">business address is&nbsp;</FONT>16690
Collins Avenue, Suite PH-1, Sunny Isles Beach, Florida 33160. Mr. Lynn does not own, and has not owned during the past two years, directly
or indirectly, beneficially or of record, any class of securities of the Company, including the Shares. <FONT STYLE="font-size: 10pt">Mr.
Lynn is a citizen of the United States of America.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 5pt 0.5in; text-align: justify; background-color: white"><I>Director Qualifications:
Mr. Lynn is well qualified to serve on the Board due to his broad business, legal and administration experience, his experience as a public
company director, and his experience in a variety of industries.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>Andrew Teno</B>, age 38, has been a portfolio manager
at Icahn Capital, the entity through which Carl C. Icahn manages investment funds, since October 2020. Mr. Teno previously worked at Fir
Tree Partners, a New York based private investment firm that invests worldwide in public and private companies, real estate and sovereign
debt, from 2011 to April 2020. Prior to that, he worked at Crestview Partners from 2009 to 2011 as an associate in their private equity
business, and at Gleacher Partners, a boutique mergers and acquisitions firm, from 2007 to 2009. Mr. Teno has been a director of: Crown
Holdings Inc. (NYSE: CCK), a global supplier of packaging products, since December 2022; FirstEnergy Corp. (NYSE: FE), an electric utility,
since March 2021; and Southwest Gas Holdings, Inc. (NYSE: SWX), an entity that purchases, distributes and transports natural gas and provides
utility infrastructure services across North America, since May 2022. Mr. Teno previously served as a director of Herc Holdings Inc. (NYSE:
HRI), an equipment rental company, from February 2021 to March 2023; Cheniere Energy, Inc. (NYSE: LNG) from February 2021 to June 2022,
and Eco-Stim Energy Solutions from March 2017 to December 2018. Carl C. Icahn has or previously had non&#8722;controlling interests in
each of Crown Holdings, FirstEnergy, Herc, Southwest Gas and Cheniere through the ownership of securities. Mr. Teno received an undergraduate
business degree from the Wharton School at the University of Pennsylvania in 2007. Mr. Teno&rsquo;s&nbsp;<FONT STYLE="background-color: white">business
address is&nbsp;</FONT>16690 Collins Avenue, Suite PH-1, Sunny Isles Beach, Florida 33160. Mr. Teno does not own, and has not owned during
the past two years, directly or indirectly, beneficially or of record, any class of securities of the Company, including the Shares. Mr.
Teno is a citizen of the United States of America.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 5pt 0.5in; background-color: white"><I>Director Qualifications: Mr. Teno is
well qualified to serve on the Board due to his broad business and investment experience, his experience as a public company director,
including as an Audit Committee member, and his familiarity with national and international business matters.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><I>Interests of the Icahn Nominees</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">If elected,
each Icahn Nominee would receive such directors&rsquo; fees as may be payable by the Company in accordance with its practice at the time
and, as a result, the Icahn Nominees may be deemed to have an interest in their nominations for election to the Board.</FONT> The Participants
expect that the Icahn Nominees, if elected, will be indemnified for service as directors of Illumina to the same extent indemnification
is provided to the current directors of Illumina under the</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Bylaws and that such individuals would be covered
by any policy of insurance under which Illumina insures its directors and officers.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="background-color: white">There are currently no understandings
or arrangements between Mr. Intrieri, on one hand, and any of the Icahn Participants or the other Icahn Nominees, on the other hand. </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Mr. Lynn is an employee of Icahn Enterprises and Mr.
Teno is an employee of Icahn Capital.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Mr. Lynn entered into a letter agreement with Icahn
Enterprises on December 9, 2021, pursuant to which Mr. Lynn is employed as General Counsel of Icahn Enterprises (the &ldquo;<U>Lynn Letter
Agreement</U>&rdquo;). Pursuant to the terms of the Lynn Letter Agreement, Mr. Lynn is an &ldquo;at-will&rdquo; employee who may be terminated
with or without cause and with or without notice, at any time. The Lynn Letter Agreement provides that Mr. Lynn is entitled to a base
salary, an annual bonus opportunity, and a grant of deferred units in Icahn Enterprises, which are subject to vesting and forfeiture pursuant
to the terms of Icahn Enterprises&rsquo; 2017 Long-Term Incentive Plan. Under the Lynn Letter Agreement, Mr. Lynn is entitled to participate
in certain benefit programs and plans of Icahn Enterprises and its affiliates. He is also subject to certain confidentiality and non-compete
obligations thereunder. The Lynn Letter Agreement does not provide for any profit-sharing or similar payments relating to the Shares or
other investments held by Icahn Partners or its affiliates.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Mr. Teno entered into an employment agreement with
Icahn Capital, an affiliate of Mr. Icahn, on October 1, 2020 (the &ldquo;<U>Teno Employment Agreement</U>&rdquo;), pursuant to which Mr.
Teno is employed as a portfolio manager. The term of the Teno Employment Agreement commenced on October 1, 2020 and ends on September
30, 2027, unless earlier terminated under the terms thereof. Pursuant to the Teno Employment Agreement, Mr. Teno is entitled to a base
salary, an annual bonus opportunity, and under certain circumstances, Mr. Teno is also eligible to receive a one-time profit-sharing payment
equal to the sum of a specified percentage of net investment gains over a specified hurdle for certain investments held by affiliates
of Icahn Capital, which such investments include the Company and its Shares. Under the Teno Employment Agreement, Mr. Teno is also entitled
to participate in certain benefit programs and plans of Icahn Capital. He is also subject to certain confidentiality and non-compete obligations
thereunder.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">From time to time, Messrs. Lynn and Teno have served
on the boards of directors of entities in which Mr. Icahn and/or his affiliates have an interest. In such situations where Mr. Icahn does
not control such entities, Messrs. Lynn and Teno receive customary director compensation from such entities (which may include cash fees,
equity awards, reimbursement of travel expenses, indemnification and the like).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Pursuant to the limited partnership agreement of Icahn
Enterprises, each of Messrs. Lynn and Teno are entitled to indemnification for certain losses and expenses incurred in connection with
proxy contests and service as a director on boards of directors of companies in which Icahn Enterprises or its affiliates have an interest
(including any service as a director on the Board).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><I>Other Disclosures</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Icahn Participants represent that (i) they intend
to, or are part of a group which intends to, deliver a proxy statement and form of proxy to holders of at least the percentage of the
Company&rsquo;s outstanding capital stock required to elect the Icahn Nominees at the Annual Meeting and (ii) they intend to, or are part
of a group which intends to, solicit the holders of shares representing at least 67% of the voting power of shares entitled to vote on
the election of directors in support of the Icahn Nominees.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Participants are required to include all nominees
for election on their &ldquo;<B><U>GOLD</U></B>&rdquo; universal proxy card. For additional information regarding the Company&rsquo;s
nominees and any other related information, please refer to the Company&rsquo;s proxy statement. You will receive solicitation materials
from the Company, including a proxy statement and a white universal proxy card. The Participants are not responsible for the accuracy
or completeness of any information provided by or relating to the Company or its nominees contained in the solicitation materials filed
or disseminated by or on behalf of the Company or any other statements that the Company makes. Stockholders will be able to obtain, free
of charge, copies of all proxy statements, any amendments or supplements thereto and any other documents (including the &ldquo;<B><U>GOLD</U></B>&rdquo;
universal proxy card) when filed by the applicable party with the SEC in connection with the annual meeting at the SEC&rsquo;s website
(http://www.sec.gov).</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Based on information in the Company&rsquo;s proxy,
the Company&rsquo;s bylaws require <FONT STYLE="background-color: white">that a director nominee be elected only if he or she receives
a majority of the votes cast with respect to his or her election in an uncontested election (that is, the number of shares voted &ldquo;FOR&rdquo;
that nominee exceeds the number of votes cast &ldquo;WITHHOLD&rdquo; for that nominee). However, t</FONT>his election of directors will
be considered a contested election and, as provided under Article III, Section 16 of the Company&rsquo;s Amended and Restated Bylaws,
directors will be elected on a plurality basis. This means that the nine (9) director nominees receiving the greatest number of votes
cast &ldquo;FOR&rdquo; their election will be elected. &ldquo;WITHHOLD&rdquo; votes and any broker&nbsp;non-votes&nbsp;will be counted
for purposes of determining whether there is a quorum at the annual meeting for this vote but will not be counted as votes cast and will
result in the applicable nominee(s) receiving fewer votes cast &ldquo;FOR&rdquo; such nominee(s).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We recommend that you vote &ldquo;<B><U>FOR</U></B>&rdquo;
each of the Icahn Nominees and &ldquo;<B><U>WITHHOLD</U></B>&rdquo; on each of the Opposed Company Nominees and each of the Acceptable
Company Nominees.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; background-color: white">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="text-transform: uppercase"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center; background-color: white"><FONT STYLE="background-color: white"><B>Proposal
2: </B></FONT><B>Ratification of the Appointment of Ernst&nbsp;&amp; Young LLP as Illumina&rsquo;s Independent Registered Public Accounting
Firm for the Fiscal Year Ending December 31, 2023</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Based on information contained in the Company&rsquo;s
proxy statement, it is expected that at the Annual Meeting the stockholders will be asked to ratify the appointment of Ernst&nbsp;&amp;
Young LLP as the Company&rsquo;s independent registered public accounting firm for the fiscal year ending December 31, 2023 at the Annual
Meeting. The Company&rsquo;s Audit Committee has appointed Ernst&nbsp;&amp; Young LLP as the independent registered public accounting
firm to audit its consolidated financial statements for the year ending December&nbsp;31, 2023, including the audit of Illumina&rsquo;s
internal control over financial reporting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">Based on information
in the Company&rsquo;s proxy, ratification of the appointment of Ernst &amp; Young LLP is not required by the Company&rsquo;s bylaws or
otherwise, but the Board is submitting Proposal 2 as a matter of good corporate governance practices. If stockholders do not ratify the
appointment of Ernst&nbsp;&amp; Young LLP, the Company&rsquo;s Audit Committee and the Board would consider such a negative vote in their
consideration of what, if any, action to take. Even if the appointment is ratified, the Company&rsquo;s Audit Committee, in its discretion,
may direct the appointment of a different independent audit firm at any time during the fiscal year if it is determined that such a change
would be in the best interests of Illumina and its stockholders. The ratification of the appointment of Ernst&nbsp;&amp; Young LLP as
the Company&rsquo;s independent registered public accounting firm requires the affirmative &ldquo;FOR&rdquo; vote of a majority of the
Shares present in person or represented by proxy and entitled to vote on Proposal 2. Abstentions on Proposal 2 have the same effect as
a vote against.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">We recommend that
you vote &ldquo;<B><U>FOR</U></B>&rdquo; the ratification of the appointment of Ernst&nbsp;&amp; Young LLP as the Company&rsquo;s independent
registered public accounting firm for the fiscal year ending December 31, 2023.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 24.5pt 0 0; background-color: white">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="background-color: white"><B>Proposal 3:
</B></FONT><B>Advisory Vote to Approve the Compensation of the Company&rsquo;s &ldquo;Named Executive Officers&rdquo;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Based on information contained in the Company&rsquo;s
proxy statement, it is expected that at the Annual Meeting the stockholders will be asked to vote, on an advisory basis, to approve the
compensation of the Company&rsquo;s &ldquo;named executive officers&rdquo; as disclosed in the &ldquo;Executive Compensation&rdquo; of
the Company&rsquo;s proxy statement. The Company has indicated in its proxy statement that its stockholders are being asked to vote on
the following advisory resolution:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.5in; text-align: justify">&ldquo;RESOLVED, that the compensation paid
to Illumina&rsquo;s named executive officers, as disclosed pursuant to Item 402 of Regulation S-K, including the Compensation Discussion
and Analysis, compensation tables, and narrative discussion, is hereby APPROVED.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.5in 0 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Proposal 3, which is known as a &ldquo;say-on-pay&rdquo;
proposal, allows the Company&rsquo;s stockholders to express their views on the compensation paid to Illumina&rsquo;s &ldquo;named executive
officers.&rdquo; Due to our belief that the Company&rsquo;s management and Board have failed to maximize value for the Company&rsquo;s
stockholders and during such time, the Company has continued to increase the compensation paid to its &ldquo;named executive officers,&rdquo;
we recommend that you vote &ldquo;<B><U>AGAINST</U></B>&rdquo; the Company&rsquo;s &ldquo;say-on-pay&rdquo; proposal.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">Based on information
in the Company&rsquo;s proxy, the vote on Proposal 3 is advisory and is not binding on the Company, its Board or its Compensation Committee
(the &ldquo;<U>Compensation Committee</U>&rdquo;). However, the Company has indicated in its proxy statement that its Board and its Compensation
Committee will review and consider the voting results when making future decisions regarding executive compensation. The approval of the
advisory resolution in Proposal 3 requires the affirmative &ldquo;FOR&rdquo; vote of a majority of the Shares present in person or represented
by proxy and entitled to vote on Proposal 3. Abstentions on Proposal 3 have the same effect as a vote against.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We recommend that you vote &ldquo;<B><U>AGAINST</U></B>&rdquo;
the approval, on an advisory basis, of the compensation of the Company&rsquo;s &ldquo;named executive officers.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="background-color: white"><B>Proposal 4:
Advisory Vote on the Frequency on Holding an Advisory Vote to Approve Compensation Provided to the Company&rsquo;s &ldquo;Named Executive
Officers&rdquo;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Based on information contained in the Company&rsquo;s
proxy statement, it is expected that at the Annual Meeting the stockholders will be asked to vote, on an advisory basis, to approve the
frequency on holding an advisory vote to approve the compensation provided to the Company&rsquo;s &ldquo;named executive officers&rdquo;.
The Company has indicated in its proxy statement that its stockholders are being asked to vote on whether future advisory votes to approve
compensation of the Company&rsquo;s &ldquo;named executive officers&rdquo; should occur every year, every two years, or every three years
pursuant to the following advisory resolution:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.5in; text-align: justify">&ldquo;RESOLVED, that the voting choice of once
every year, once every two years, or once every three years that receives the highest number of votes cast in connection with this resolution
will be considered to be the frequency preferred by stockholders on an advisory basis for Illumina to hold a&nbsp;non-binding&nbsp;vote
to approve the compensation provided to our named executive officers.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.5in 0 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Company&rsquo;s proxy statement indicates that
the Board has determined that, consistent with past practice, holding an advisory vote on executive compensation every year (annually)
is the most appropriate policy for the Company at this time, and recommends that the Company&rsquo;s stockholders vote to hold annual
advisory votes on executive compensation.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">Based on information
in the Company&rsquo;s proxy, the vote on Proposal 4 is advisory and is not binding on the Company, or its Board. However, the Company
has indicated in its proxy statement that its Board will consider the outcome, along with other relevant factors, in determining how often
to conduct advisory votes on executive compensation. Based on the Company&rsquo;s proxy, approval of the advisory resolution set forth
above with respect to holding an advisory vote once every year, once every two years, or once every three years, as applicable, requires
the affirmative vote of a majority of the Shares present in person or represented in proxy and entitled to vote on Proposal 4. The Company
has indicated in its proxy that if none of the frequency alternatives (one year, two years, or three years) receives a majority vote,
the Company will consider the frequency that receives the highest number of votes to be the frequency that has been selected by the stockholders,
on an advisory basis.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We recommend that you vote &ldquo;<B><U>1 YEAR</U></B>&rdquo;
on the proposal to approve, on an advisory basis, the frequency of holding an advisory vote to approve the compensation provided to the
Company&rsquo;s &ldquo;named executive officers&rdquo;.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="background-color: white"><B>Proposal 5:
</B></FONT><B>Vote to Approve Certain Amendments to the Illumina, Inc. 2015 Stock and Incentive Plan</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Based on information contained in the Company&rsquo;s
proxy statement, it is expected that at the Annual Meeting the stockholders will be asked to vote to approve certain amendments to the
Illumina, Inc. 2015 Stock and Incentive Plan (the &ldquo;<U>2015 Plan</U>&rdquo;). The Company has indicated in its proxy statement that
its stockholders are being asked to vote on the following resolution:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.5in; text-align: justify">&ldquo;RESOLVED, that the Stockholder Approval
Terms including in the Illumina, Inc. Amended and Restated 2015 Stock and Incentive Plan, as set forth in Annex A to the Company&rsquo;s
proxy statement, are hereby approved and authorized.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0.5in 0 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Company&rsquo;s proxy states that on February
1, 2023, the Board approved the amended and restated version of the 2015 Plan, which is referred to therein as the &ldquo;<U>Amended 2015
Plan</U>&rdquo; and included as Annex A to the Company&rsquo;s proxy statement. Based on information in the Company&rsquo;s proxy statement,
the Amended 2015 Plan reflects the following changes:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Adds 8&nbsp;million additional shares for issuance
under the Amended 2015 Plan (the &ldquo;<U>2023 Share Reserve Increase</U>&rdquo;);</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Extends the termination date of the Amended 2015
Plan, and the ability to grant incentive stock options, to January&nbsp;31, 2033 (the &ldquo;<U>Plan Term Extension</U>&rdquo;);</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Limits the administrator&rsquo;s authority to
accelerate vesting or waive forfeiture conditions to a termination resulting from the holder&rsquo;s death or disability;</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Provides that any dividend equivalent rights
will be subject to the same vesting conditions as the award to which they relate;</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Adds vesting protections for awards that are
assumed in a change in control in the event the holder is involuntarily terminated by the acquirer within 24 months of the change in control;
and</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; background-color: white">Updates terms to reflect
changes in applicable laws (e.g., removal of certain inoperative provisions due to changes in Section&nbsp;162(m) of the Code).</FONT></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">The Company&rsquo;s
proxy statement indicates that only the 2023 Share Reserve Increase and the Plan Term Extension (which are referred to as the &ldquo;<U>Stockholder
Approval Terms</U>&rdquo;) require stockholder approval. Based on information in the Company&rsquo;s proxy statement, if stockholders
do not approve the Stockholder Approval Terms, then the term of the Amended 2015 Plan will remain as January 29, 2025, and all awards
which have been granted under the Amended 2015 Plan in contemplation of the 2023 Share Reserve Increase will be settled in cash instead
of shares, but all other changes to the 2015 Plan as reflected in the Amended 2015 Plan will be given full effect. </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">Based on information
in the Company&rsquo;s proxy statement, the approval of the resolution in Proposal 5 requires the affirmative &ldquo;<U>FOR</U>&rdquo;
vote of a majority of the outstanding Shares, voting as a single class. Abstentions on Proposal 5 have the same effect as a vote against.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">We make no recommendation on the vote to approve certain
amendments to the Illumina, Inc. 2015 Stock and Incentive Plan.</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Other Proposals</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Except as set forth in this Proxy Statement, the Icahn
Participants are not aware of any other matter to be considered at the Annual Meeting. However, if the Icahn Participants learn of any
other proposals made at a reasonable time before the Annual Meeting, the Icahn Participants will either supplement this Proxy Statement
and provide stockholders with an opportunity to vote by proxy directly on such matters or will not exercise discretionary authority with
respect thereto. If other proposals are made thereafter, the persons named as proxies on the&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy
card solicited by the Icahn Participants will vote such proxies in their discretion.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If you sign and return the <B><U>GOLD</U></B> universal
proxy card or, if applicable, the <B><U>GOLD</U></B> voting instruction form, your Shares will be voted in accordance with your specifications.
If no direction is indicated with respect to the foregoing proposals, you will be deemed to have given a direction to vote the Shares
represented by the&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy card or, if applicable, the <B><U>GOLD</U></B> voting instruction form
(1) &ldquo;<B><U>FOR</U></B>&rdquo; each of the Icahn Nominees and to &ldquo;<B><U>WITHHOLD</U></B>&rdquo; on each of the Opposed Company
Nominees and each of the Acceptable Company Nominees, (2) &ldquo;<B><U>FOR</U></B>&rdquo; the ratification of the appointment of Ernst
&amp; Young LLP as the Company&rsquo;s independent registered public accounting firm for the fiscal year ending December 31, 2023, (3)
&ldquo;<B><U>AGAINST</U></B>&rdquo; the approval, on an advisory basis, of the compensation of the &ldquo;named executive officers&rdquo;
as disclosed in the Company&rsquo;s proxy statement, (4) &ldquo;<B><U>1 YEAR</U></B>&rdquo; on the proposal to approve, on an advisory
basis, the frequency of holding an advisory vote to approve the compensation provided to the Company&rsquo;s &ldquo;named executive officers&rdquo;,
(5) &ldquo;<B><U>ABSTAIN</U></B>&rdquo; on the approval of the amendments to the Illumina, Inc. 2015 Stock and Incentive Plan, and (6)
in the proxy holders&rsquo; discretion as to other matters that may come before the Annual Meeting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>RECORD DATE; VOTING; PROXY PROCEDURES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>Record Date</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Company has set the close of business on April
3, 2023 as the Record Date for determining stockholders entitled to notice of and to vote at the Annual Meeting. The mailing address of
the principal executive offices of the Company is 5200 Illumina Way, San Diego, CA 92122. Stockholders of record at the close of business
on the Record Date will be entitled to vote at the Annual Meeting. According to the Company, as of the Record Date, there were <FONT STYLE="background-color: white">158,032,030</FONT>
Shares outstanding.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>Voting and Proxy Procedures </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Only stockholders of record on the Record Date will
be entitled to notice of and to vote at the Annual Meeting. Stockholders who sell their Shares before the Record Date (or acquire them
without voting rights after the Record Date) may not vote such Shares. Stockholders of record on the Record Date will retain their voting
rights in connection with the Annual Meeting even if they sell their Shares after the Record Date.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Each of the Participants and the Company will be using
a universal proxy card for voting on the election of directors at the Annual Meeting, which will include the name of all nominees for
the election to the Board. Stockholders have the ability to vote for up to nine (9) nominees on the enclosed <B><U>GOLD</U></B> universal
proxy card. <B>Accordingly, there is no need to use the Company&rsquo;s white proxy card or voting instruction form, regardless of how
you wish to vote</B>.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">You may vote &ldquo;FOR&rdquo; up to a total of nine
(9) nominees. If you vote using the <B><U>GOLD</U></B> universal proxy card for less than nine (9) nominees, your shares will be voted
&ldquo;FOR&rdquo; only those nominees you have marked.&nbsp;If you vote using the&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy card &ldquo;FOR&rdquo;
more than nine (9) nominees, your votes on Proposal 1 regarding the nominees will be invalid and will not be counted.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><I>&nbsp;</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><I>Stockholders of Record:</I> If your Shares are
held in your own name, please authorize a proxy to vote by signing and returning the enclosed&nbsp;<B><U>GOLD</U>&nbsp;</B>universal proxy
card using the postage-paid envelope provided.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><I>Street Name Holders:</I> If you hold your Shares
in the name of one or more banks, brokerage firms, dealers, trust companies or other custodians, only they can vote your Shares and only
upon receipt of your specific instructions. Accordingly, you should complete, sign, date and return the enclosed <B><U>GOLD</U></B> voting
instruction form or vote via the Internet by following the directions provided to you by your broker or bank custodian or contact the
person responsible for your account and give instructions to them to sign and return a <B><U>GOLD</U></B> universal proxy card representing
your Shares to elect the Icahn Nominees to the Board.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Shares represented by properly executed <B><U>GOLD</U></B>
universal proxy cards will be voted at the Annual Meeting as marked.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If a stockholder returns a <B><U>GOLD</U></B> universal
proxy card or, if applicable, a <B><U>GOLD</U></B> voting instruction form that is signed, dated and not marked with respect to a proposal,
that stockholder will be deemed to have given direction to vote (1) &ldquo;<B><U>FOR</U></B>&rdquo; each of the Icahn Nominees and to
&ldquo;<B><U>WITHHOLD</U></B>&rdquo; on each of the Opposed Company Nominees and each of the Acceptable Company Nominees, (2) &ldquo;<B><U>FOR</U></B>&rdquo;
the ratification of the appointment of Ernst &amp; Young LLP as the Company&rsquo;s independent registered public accounting firm for
the fiscal year ending December 31, 2023, (3) &ldquo;<B><U>AGAINST</U></B>&rdquo; the approval, on an advisory basis, of the compensation
of the &ldquo;named executive officers&rdquo; as disclosed in the Company&rsquo;s proxy statement, (4) &ldquo;<B><U>1 YEAR</U></B>&rdquo;
on the proposal to approve, on an advisory basis, the frequency of holding an advisory vote to approve the compensation provided to the
Company&rsquo;s &ldquo;named executive officers&rdquo;, (5) &ldquo;<B><U>ABSTAIN</U></B>&rdquo; on the approval of the amendments to the
Illumina, Inc. 2015 Stock and Incentive Plan, and (6) in the proxy holders&rsquo; discretion as to other matters that may come before
the Annual Meeting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>Quorum; Discretionary Voting; Broker Non-Votes</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">A quorum is the minimum number of Shares that must
be represented at a duly called meeting of stockholders virtually or represented by proxy, in order to legally conduct business at the
meeting. According to Illumina&rsquo;s proxy statement,</P>


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    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">a quorum requires the presence of the holders of a
majority of the Shares entitled to vote represented in person or by proxy at the Annual Meeting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">According to Illumina&rsquo;s proxy statement, abstentions
and instructions to withhold authority to vote will be treated as Shares that are present and entitled to vote for the purposes of determining
whether a quorum exists. Abstentions and instructions to withhold authority will not be counted as votes cast and will have no effect
on the outcome of the vote.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If you are a stockholder of record, you must deliver
your vote on the&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy card, the Company&rsquo;s white proxy card or virtually attend the Annual
Meeting in order to be counted in the determination of a quorum.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If your Shares are held in the name of your bank,
brokerage firm, dealer, trust company or other custodian, that party will give you instructions for voting your Shares. If you do not
give your voting instructions to your bank, brokerage firm, dealer, trust company or other custodian, it will not be allowed to vote your
Shares with respect to the election of directors or any additional proposals which may be presented at the Annual Meeting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If you are the beneficial owner of Shares, your broker
or nominee may vote your Shares only on those matters on which it has discretion to vote. Under the applicable rules, your broker or nominee
does not have discretion to vote your Shares on&nbsp;non-routine&nbsp;matters.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">According to the Company&rsquo;s proxy statement,
Proposal 1 (the election of directors), Proposal 3 (the advisory vote on the compensation provided to the Company&rsquo;s &ldquo;named
executive officers&rdquo;), Proposal 4 (the advisory vote on the frequency on holding an advisory vote to approve the compensation provided
to the Company&rsquo;s &ldquo;named executive officers&rdquo;), and Proposal 5 (the approval of certain amendments to the Illumina, Inc.
2015 Stock and Incentive Plan) are considered &ldquo;non-discretionary&rdquo; items. This means brokerage firms that have not received
voting instructions from their clients on these proposals may not vote on them. According to the Company&rsquo;s proxy statement, these
so-called &ldquo;broker non-votes&rdquo; will not be considered in determining the number of votes necessary for approval for non-discretionary
matters and, as a result, will have no effect on the Company&rsquo;s ability to obtain a quorum and will not otherwise affect the outcome
of the votes for Proposals 1, 3, 4 and 5. If this Proxy Statement has been provided to you by your broker or nominee at the request of
the Participants, your broker or nominee does not have discretion to vote your Shares on routine matters such as Proposal 2 (ratification
of the appointment of Ernst &amp; Young LLP as the Company&rsquo;s independent registered public accounting firm for the fiscal year ended
December 31, 2023) and may vote your shares on Proposal 2 only pursuant to your specific voting instructions.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>Revocation of Proxies</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Stockholders of the Company may revoke their proxies
at any time prior to exercise by attending the Annual Meeting and voting in person (although attendance at the Annual Meeting will not
in and of itself constitute revocation of a proxy), by delivering a written notice of revocation, or by signing and delivering a subsequently
dated proxy which is properly completed. The revocation may be delivered either to Icahn Partners in care of HKL &amp; Co., LLC at the
address set forth on the back cover of this Proxy Statement or to Illumina at 5200 Illumina Way, San Diego, CA 92122, or any other address
provided by the Company. Although a revocation is effective if delivered to the Company, we request that either the original or photostatic
copies of all revocations be mailed to Icahn Partners in care of HKL &amp; Co., LLC at the address set forth on the back cover of this
Proxy Statement so that we will be aware of all revocations and can more accurately determine if and when proxies have been received from
the holders of record on the Record Date of a majority of the outstanding Shares.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Stockholder
Proposals</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0">Under SEC Rule 14a-8, a stockholder
who intends to present a proposal at the Company&rsquo;s 2024 annual meeting of stockholders (other than a director nomination) and who
wishes the proposal to be included in the Company&rsquo;s proxy statement for that meeting must submit the proposal in writing to the
Company&rsquo;s principal executive offices. The proposal must be received no later than December 23, 2023. The proposal and its proponent
must satisfy all applicable requirements of Rule 14a-8.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0">The Company&rsquo;s Bylaws permit
a stockholder or group of stockholders (up to 20) who have owned at least three percent of the Company&rsquo;s Shares for at least three
years to submit director nominees (up to the greater of two nominees or 20% of the Board, as determined in accordance with the Bylaws)
for inclusion in the Company&rsquo;s proxy statement if the nominating stockholder(s) satisfies the requirements specified in the Bylaws.
With respect to stockholder nominees for director election submitted for inclusion in Company&rsquo;s proxy statement for its 2024 annual
meeting, written notice of nominations by the stockholder proponent(s) must comply with the Company&rsquo;s Bylaws and must be delivered
to, or mailed and received by, the Company&rsquo;s Corporate Secretary between November 22, 2023 and December 22, 2023. These deadlines
are based on the 150th day and 120th day, respectively, before the one-year anniversary of the date of the proxy statement for the Company&rsquo;s
2023 annual meeting (which date, for purposes of the bylaws, is April 20, 2023). The ability to include a nominee in the Company&rsquo;s
proxy statement is subject to the terms and conditions set forth in the Company&rsquo;s Bylaws.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0"><FONT STYLE="background-color: white">With
respect to stockholder nominees for director election at the Company&rsquo;s 2024 annual meeting (other than nominees submitted for inclusion
in the Company&rsquo;s proxy materials) and stockholder proposals for consideration at the Company&rsquo;s 2024 annual meeting that are
not submitted for inclusion in the Company&rsquo;s proxy materials under&nbsp;Rule&nbsp;14a-8,&nbsp;written notice of nominations and
proposals must be provided by the stockholder proponent to the Company in accordance with the Company&rsquo;s Bylaws. The notice must
be delivered to, or mailed and received by, the Company&rsquo;s Corporate Secretary between </FONT>January 26, 2024 <FONT STYLE="background-color: white">and
</FONT>February 25, 2024 <FONT STYLE="background-color: white">and must comply with all applicable provisions of the Company&rsquo;s Bylaws.
You may obtain a copy of the Company&rsquo;s Bylaws by writing to the Company&rsquo;s Corporate Secretary at Illumina, Inc., </FONT>5200
Illumina Way, San Diego, CA 92122.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin-right: 0; margin-left: 0">The information set forth above
regarding the procedures for submitting stockholder proposals for consideration at the Company&rsquo;s 2024 annual meeting is based on
information contained in the Company&rsquo;s proxy statement and the Bylaws. The incorporation of this information in this Proxy Statement
should not be construed as an admission by the Participants that such procedures are legal, valid or binding.</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Certain
Additional Information</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">WE HAVE OMITTED FROM THIS PROXY STATEMENT CERTAIN
DISCLOSURE REQUIRED BY APPLICABLE LAW THAT IS EXPECTED TO BE INCLUDED IN THE COMPANY&rsquo;S PROXY STATEMENT RELATING TO THE ANNUAL MEETING
BASED ON OUR RELIANCE ON RULE 14A-5(C) UNDER THE EXCHANGE ACT. THIS DISCLOSURE IS EXPECTED TO INCLUDE, AMONG OTHER THINGS, CURRENT BIOGRAPHICAL
INFORMATION ON THE COMPANY&rsquo;S DIRECTORS AND EXECUTIVE OFFICERS, INFORMATION CONCERNING EXECUTIVE COMPENSATION AND DIRECTOR COMPENSATION,
INFORMATION CONCERNING THE COMMITTEES OF THE BOARD AND OTHER INFORMATION CONCERNING THE BOARD, INFORMATION CONCERNING CERTAIN RELATIONSHIPS
AND RELATED PARTY TRANSACTIONS, INFORMATION ABOUT THE COMPANY&rsquo;S INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM AND OTHER IMPORTANT
INFORMATION.&nbsp;<B>STOCKHOLDERS ARE DIRECTED TO REFER TO THE COMPANY&rsquo;S PROXY STATEMENT FOR THE FOREGOING INFORMATION, INCLUDING
INFORMATION REQUIRED BY ITEM 7 OF SCHEDULE 14A WITH REGARD TO THE COMPANY&rsquo;S NOMINEES. STOCKHOLDERS CAN ACCESS THE COMPANY&rsquo;S
PROXY STATEMENT AND ANY OTHER RELEVANT DOCUMENTS DISCLOSING THIS INFORMATION, WITHOUT COST, ON THE SEC&rsquo;S WEBSITE AT WWW.SEC.GOV.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>SOLICITATION OF PROXIES; EXPENSES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The solicitation of proxies pursuant to this Proxy
Statement is being made by the Participants. Proxies may be solicited through the mail, press releases and other public statements, electronic
communications, facsimile, telephone and in-person meetings. Each of the Icahn Nominees, the other Participants named in this Proxy Statement,
and employees of the Icahn Participants may assist in the solicitation of proxies without any additional remuneration.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The Participants have retained <FONT STYLE="background-color: white">HKL
&amp; Co., LLC </FONT>to provide solicitation and advisory services in connection with this solicitation. <FONT STYLE="background-color: white">HKL
&amp; Co., LLC </FONT>will be paid a fee not to exceed $150,000 based upon the campaign services provided. In addition, the Participants
will reimburse <FONT STYLE="background-color: white">HKL &amp; Co., LLC </FONT>for its reasonable out-of-pocket expenses and will indemnify
<FONT STYLE="background-color: white">HKL &amp; Co., LLC </FONT>against certain liabilities and expenses, including certain liabilities
under the federal securities laws. <FONT STYLE="background-color: white">HKL &amp; Co., LLC </FONT>will solicit proxies from individuals,
banks, brokerage firms, dealers, trust companies, other custodians and other institutional holders. It is anticipated that <FONT STYLE="background-color: white">HKL
&amp; Co., LLC </FONT>will employ up to 35 persons to solicit the Company&rsquo;s stockholders as part of this solicitation. <FONT STYLE="background-color: white">HKL
&amp; Co., LLC </FONT>does not believe that any of its directors, officers, employees, affiliates or controlling persons, if any, is a
&ldquo;participant&rdquo; in this proxy solicitation. The costs related to this proxy solicitation will be borne by the Participants.
Costs of this Proxy Solicitation are currently estimated to be approximately $700,000. The actual amount could be higher or lower depending
on the facts and circumstances arising in connection with the solicitation. We estimate that through the date hereof, the Participants&rsquo;
expenses in connection with this Proxy Solicitation are approximately $200,000. If successful, the Participants may seek reimbursement
of these costs from the Company.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">In the event that the Participants decide to seek
reimbursement of their expenses, the Participants do not intend to submit the matter to a vote of the Company&rsquo;s stockholders. The
Board would be required to evaluate the requested reimbursement consistent with its fiduciary duties to the Company and its stockholders.
Costs related to the solicitation of proxies include expenditures for attorneys, public relations and other advisors, solicitors, printing,
advertising, postage, transportation and other costs incidental to the solicitation.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">If you have any questions or require any assistance
with voting your Shares, please contact our proxy solicitor, <FONT STYLE="background-color: white">HKL &amp; Co., LLC</FONT>: Banks and
Brokerage Firms Please Call Collect: +1 (212) 468-5380; All Others Call Toll-Free: +1 (800) 257-3995; Email: ILMN@hklco.com.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B><U>QUESTIONS AND ANSWERS ABOUT THE PROXY MATERIALS
AND THE ANNUAL MEETING</U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; background-color: white"><B><I>&nbsp;</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white"><B>Q: What are you
asking Illumina&rsquo;s stockholders to do?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white">A: We are asking for
support for the election of our three director candidates, <B>Vincent J. Intrieri</B>, <FONT STYLE="background-color: white"><B>Jesse
A. Lynn</B>, and <B>Andrew J. Teno</B></FONT>, to the Board. As described more fully in this Proxy Statement, we believe our director
candidates will add valuable perspectives and leadership to the Board. We believe our candidates possess the skills, experience, energy
and leadership abilities necessary to contribute to Illumina as well-rounded Board members. Our director candidates will be active and
responsible stewards of the trust placed in them by the stockholders and <FONT STYLE="background-color: white">will represent, and will
seek the best possible results for, all of Illumina&rsquo;s stockholders.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white">Stockholders are permitted
to vote for any combination (up to nine (9) total) of the Icahn Nominees and the Company&rsquo;s nominees on the&nbsp;<B><U>GOLD</U></B>&nbsp;universal
proxy card. However, if stockholders choose to vote for any of the Company&rsquo;s nominees, we recommend that stockholders &ldquo;<B><U>WITHHOLD</U></B>&rdquo;
on Francis A. deSouza, Robert S. Epstein, and John W. Thompson, who we refer to as the &ldquo;<U>Opposed Company Nominees</U>.&rdquo;
The Company&rsquo;s other six (6) nominees (Frances Arnold, Caroline D. Dorsa, Scott Gottlieb, Gary S. Guthart, Philip W. Schiller and
Susan E. Siegel) are referred to hereafter as the &ldquo;<U>Acceptable Company Nominees</U>.&rdquo; We make no recommendation on the Acceptable
Company Nominees. We believe the best opportunity for the Icahn Nominees to be elected is by voting &ldquo;<B><U>FOR</U></B>&rdquo; each
of the Icahn Nominees and to &ldquo;<B><U>WITHHOLD</U></B>&rdquo; on or not vote &ldquo;for&rdquo; the Opposed Company Nominees on the
<B><U>GOLD</U></B> universal proxy card.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white"><B>Q: Who are your
director candidates?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">A: Vincent J. Intrieri, <FONT STYLE="background-color: white">Jesse
A. Lynn, and Andrew J. Teno are highly qualified individuals with significant business and public company director experience. The principal
occupation and business experience of each of these candidates is described in this Proxy Statement in the section titled &ldquo;<I>Matters
to be Considered at the Annual Meeting&mdash;Proposal 1: Election of the Icahn Nominees&mdash;Biographical Information About the Icahn
Nominees</I>.&rdquo; We believe that each of our director candidates would be considered independent under the applicable rules of the
Nasdaq and Illumina&rsquo;s corporate governance guidelines, and none of our director candidates are affiliated with Illumina or any of
its subsidiaries. If elected to the Board, our director candidates would owe fiduciary duties to all of Illumina&rsquo;s stockholders.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt"><B>Q: Who is entitled to vote?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">A: Only holders of voting stock at the close
of business on the Record Date, April 3, 2023, are entitled to notice of and to vote at the Annual Meeting. Stockholders who sold Shares
before the Record Date (or acquire them without voting rights after the Record Date) may not vote such Shares. Stockholders of record
on the Record Date will retain their voting rights in connection with the Annual Meeting even if they sell such Shares after the Record
Date (unless they also transfer their voting rights).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white"><B>Q: How important
is my vote? </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white">A: Your vote is important,
no matter how few Shares you own. The Participants urge you to sign, date, and return the enclosed <B><U>GOLD</U></B> universal proxy
card or, if applicable, the enclosed <B><U>GOLD</U></B> voting instruction form today to elect the Icahn Nominees. The Board will ultimately
be comprised of the nine (9) nominees who receive the most votes cast in favor or his or her election at the Annual Meeting. <B>We urge
you to vote in favor of the Icahn Nominees.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; background-color: white"><B>Q: How do I vote my Shares?&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">A: <I>Shares held in record name.</I> If your
Shares are registered in your own name, please vote today by signing, dating and returning the enclosed <B><U>GOLD</U></B> universal proxy
card in the postage-paid envelope provided. Execution and delivery of a proxy by a record holder of Shares will be presumed to be a proxy
with respect to all Shares held by such record holder unless the proxy specifies otherwise.</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify"><I>Shares beneficially owned or held in &ldquo;street&rdquo;
name.</I> If you hold your Shares in &ldquo;street&rdquo; name with a bank, brokerage firm, dealer, trust company or other custodian,
only that party can exercise the right to vote with respect to the Shares that you beneficially own through such party and only upon receipt
of your specific instructions. <U>Accordingly, it is critical that you promptly give instructions to your broker, bank, dealer, trust
company or other nominee to vote for the Icahn Nominees</U>. Please follow the instructions to vote provided on the enclosed <B><U>GOLD</U></B>
voting instruction form. If your broker, bank, dealer, trust company, or other nominee provides for proxy instructions to be delivered
to them via the Internet, instructions will be included on the enclosed <B><U>GOLD</U></B> voting instruction form. We urge you to confirm
in writing your instructions to the person responsible for your account and provide a copy of those instructions by emailing them to ILMN@hklco.com
or mailing them to Icahn Capital LP, c/o <FONT STYLE="background-color: white">HKL &amp; Co., LLC</FONT>, 3 Columbus Circle, 15<SUP>th</SUP>
Floor, New York, NY 10019, so that we will be aware of all instructions given and can attempt to ensure that such instructions are followed.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">If you vote and return both our <B><U>GOLD</U></B>
universal proxy card and Illumina&rsquo;s white proxy card, only the latest dated proxy card will be counted.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; background-color: white"><B>Q: What is a quorum?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">A: A quorum is the minimum number of Shares that must
be represented at a duly called meeting of stockholders in person or by proxy in order to legally conduct business at the meeting. According
to Illumina&rsquo;s proxy statement, a quorum requires the presence of the holders of a majority of the Shares entitled to vote represented
in person or by proxy at the Annual Meeting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white"><B>Q: How do you recommend
that the Company&rsquo;s stockholders vote with respect to the Company&rsquo;s nominees?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">A: We recommend that the Company&rsquo;s stockholders
&ldquo;<B><U>WITHHOLD</U></B>&rdquo; on Francis A. deSouza, Robert S. Epstein, and John W. Thompson, who we refer to as the &ldquo;<U>Opposed
Company Nominees</U>.&rdquo; The Company&rsquo;s other six (6) nominees (Frances Arnold, Caroline D. Dorsa, Scott Gottlieb, Gary S. Guthart,
Philip W. Schiller and Susan E. Siegel) are referred to hereafter as the &ldquo;<U>Acceptable Company Nominees</U>.&rdquo; We make no
recommendation on the Acceptable Company Nominees. We believe the best opportunity for the Icahn Nominees to be elected will arise if
stockholders vote &ldquo;<B><U>FOR</U></B>&rdquo; each of the Icahn Nominees and to &ldquo;<B><U>WITHHOLD</U></B>&rdquo; on or not vote
&ldquo;for&rdquo; the Opposed Company Nominees on the <B><U>GOLD</U></B> universal proxy card.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; background-color: white"><B>Q: What should I do if I receive a white
proxy card from the Company?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white">A: Each of the Participants
and the Company will be using a universal proxy card for voting on the election of directors at the Annual Meeting, which will include
the name of all nominees for the election to the Board. Stockholders have the ability to vote for up to nine (9) nominees on the enclosed
<B><U>GOLD</U></B> universal proxy card. <B>Accordingly, there is no need to use the Company&rsquo;s white proxy card or voting instruction
form, regardless of how you wish to vote</B>.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white">Only the latest validly
executed proxy or, if applicable, voting instruction form that you submit will be counted; any proxy or, if applicable, voting instruction
form may be revoked at any time prior to its exercise at the Annual Meeting by following the instructions below under &ldquo;<I>Can I
change my vote or revoke my proxy</I>?&rdquo; If you have any questions or require any assistance with voting your Shares, please contact
our proxy solicitor, <FONT STYLE="background-color: white">HKL &amp; Co., LLC</FONT>, 3 Columbus Circle, 15<SUP>th</SUP> Floor, New York,
NY 10019; Banks and Brokerage Firms Please Call Collect: +1 (212) 468-5380; All Others Call Toll-Free: +1 (800) 257-3995; Email: ILMN@hklco.com.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white"><B>Q: What if I submit
a proxy card with more than nine (9) nominees selected in Proposal 1?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white">A: You may vote &ldquo;FOR&rdquo;
up to a total of nine (9) nominees. Each of the Participants and the Company will be using a universal proxy card for voting on the election
of directors at the Annual Meeting, which will include the name of all nominees for the election to the Board. Stockholders have the ability
to vote for up to nine (9) nominees on the enclosed <B><U>GOLD</U></B> universal proxy card. <B>Accordingly, there is no need to use the
Company&rsquo;s white proxy card or voting instruction form, regardless of how you wish to vote</B>.</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify; background-color: white">If you vote using
the <B><U>GOLD</U></B> universal proxy card for less than nine (9) nominees, your shares will be voted &ldquo;FOR&rdquo; only those nominees
you have marked.&nbsp;If you vote using the&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy card &ldquo;FOR&rdquo; more than nine (9) nominees,
your votes on Proposal 1 regarding the nominees will be invalid and will not be counted.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; background-color: white"><B>Q: Can I change my vote or revoke my
proxy?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">A: If you are the stockholder of record, you
may change your proxy instructions or revoke your proxy at any time before your proxy is voted at the Annual Meeting. Proxies may be revoked
by any of the following actions:</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>signing,
dating and returning the enclosed <B><U>GOLD</U></B> universal proxy card (the latest dated proxy is the only one that counts);</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>delivering
a written revocation or a later dated proxy for the Annual Meeting to Icahn Capital LP, c/o <FONT STYLE="background-color: white">HKL
&amp; Co., LLC, </FONT>3 Columbus Circle, 15<SUP>th</SUP> Floor, New York, NY 10019, or to the secretary of the Company;</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>delivering
a written revocation or a later dated proxy for the Annual Meeting to the secretary of the Company or to the Company&rsquo;s proxy solicitor;
or</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>attending
the Annual Meeting and voting (although attendance at the Annual Meeting will not, by itself, revoke a proxy).</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">If your Shares are held by a bank, brokerage
firm, dealer, trust company or other custodian, you should follow the instructions provided by your bank, brokerage firm, dealer, trust
company or other custodian to have your Shares voted. If you attend the Annual Meeting and you beneficially own Shares but are not the
record owner, your mere attendance at the Annual Meeting WILL NOT be sufficient to revoke your prior vote. You must have written authority
from the record owner to vote your Shares held in its name at the meeting. If you have any questions or require any assistance, contact
our proxy solicitor, <FONT STYLE="background-color: white"><B>HKL &amp; Co., LLC </B></FONT><B>- Banks and Brokerage Firms Please Call
Collect: +1 (212) 468-5380; All Others Call Toll-Free: +1 (800) 257-3995; Email: ILMN@hklco.com.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify"><B>IF YOU HAVE ALREADY VOTED USING THE COMPANY&rsquo;S
WHITE PROXY CARD, WE URGE YOU TO REVOKE IT BY FOLLOWING THE INSTRUCTIONS ABOVE.</B> Although a revocation is effective if delivered to
the Company, we request that either the original or a copy of any revocation be mailed to Icahn Capital LP, c/o <FONT STYLE="background-color: white">HKL
&amp; Co., LLC</FONT>, 3 Columbus Circle, 15<SUP>th</SUP> Floor, New York, NY 10019.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify"><B>Q: What is the deadline for providing a
proxy?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">A: We urge you to submit your proxy to us or,
if applicable, your voting instruction form to your custodian broker or bank as soon as possible. For your proxy to be voted at the Annual
Meeting, we must receive it on or prior to the date of the Annual Meeting. The Annual Meeting is being held virtually on May 25, 2023
at 10:00 a.m. (Pacific time). If your shares are held for you by a custodian bank or broker, consult with your custodian bank or broker
to ascertain the deadline for submitting voting instructions.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt"><B>Q: Who is making this proxy solicitation?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">A: The solicitation of proxies pursuant to
this proxy solicitation is being made by the Participants. Proxies may be solicited by mail, facsimile, telephone, Internet, virtually
and by advertisements. The Participants will solicit proxies from individuals, banks, brokerage firms, dealers, trust companies, other
custodians and other institutional holders. The Participants have requested banks, brokerage firms, dealers, trust companies or other
custodians to forward all solicitation materials to the beneficial owners of the Shares they hold of record. The Participants will reimburse
these record holders for their reasonable out-of-pocket expenses in so doing. It is anticipated that certain regular employees of the
Icahn Participants will also participate in the solicitation of proxies. Such employees will receive no additional consideration if they
assist in the solicitation of proxies.&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt"><B>Q: Why are you making this proxy solicitation?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">A: We believe that the Board&rsquo;s past mistakes,
in particular with respect to the GRAIL transaction, demonstrate that Illumina is in critical need of new leadership at the Board level.
We are confident that our highly qualified independent director candidates will add valuable perspectives and leadership to the Board.
We believe our candidates possess the</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">skills, experience, energy and leadership abilities
necessary to contribute to Illumina as well-rounded Board members. Our director candidates will be active and responsible stewards of
the trust placed in them by the stockholders.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0; background-color: white"><B>Q: Where can I find additional information
concerning Illumina and the Annual Meeting?</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">A: Pursuant to Rule 14a-5(c) promulgated under
the Exchange Act, we have omitted from this Proxy Statement certain disclosure required by applicable law to be included in Illumina&rsquo;s
proxy statement in connection with the Annual Meeting which can be found on the SEC&rsquo;s website at https://www.sec.gov,
including:</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>Item
1 of Schedule 14A (date, time and place of the Annual Meeting);</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>Item
5 of Schedule 14A (interest of certain persons in matters to be acted upon, other than the Participants);</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>Item
6 of Schedule 14A (voting securities and principal holders thereof, other than the Participants);</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>Item
7 of Schedule 14A (information about directors and executive officers and corporate governance matters);</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>Item
8 of Schedule 14A (compensation of directors and executive officers);</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>Item
9 of Schedule 14A (independent public accountants);</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>Informing
concerning the proposal regarding the approval, on an advisory basis, of the compensation provided to the Company&rsquo;s &ldquo;named
executive officers&rdquo;;</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>Information
concerning the proposal regarding the approval, on an advisory basis, of the frequency on holding an advisory vote to approve compensation
provided to the Company&rsquo;s &ldquo;named executive officers&rdquo;; and</TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif"><TR STYLE="vertical-align: top"><TD STYLE="width: 20px"></TD><TD STYLE="width: 20px">&#8226;</TD><TD>Information
concerning the proposal to approve certain amendments to the Illumina, Inc. 2015 Stock and Incentive Plan.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.5in; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify"><FONT STYLE="background-color: white">Please
refer to the Company&rsquo;s proxy statement for such information. Except as otherwise noted herein, the information in this Proxy Statement
concerning the Company has been taken from or is based upon documents and records on file with the SEC and other publicly available information.
</FONT><FONT STYLE="font-size: 10pt">We take no responsibility for the accuracy or completeness of information contained in Illumina&rsquo;s
proxy statement. </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">This Proxy Statement and all other solicitation
materials in connection with this proxy solicitation will be available on the Internet, free of charge, on the SEC&rsquo;s website at
https://www.sec.gov.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify"><B>Q: Who should I call if I have any questions?
</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">A: If you have any questions, require any assistance
in voting your Shares, need additional copies of our proxy materials, or have any other questions, please contact our proxy solicitor,
<FONT STYLE="background-color: white">HKL &amp; Co., LLC</FONT>, 3 Columbus Circle, 15<SUP>th</SUP> Floor, New York, NY 10019; Banks and
Brokerage Firms Please Call Collect: +1 (212) 468-5380; All Others Call Toll-Free: +1 (800) 257-3995; Email: ILMN@hklco.com.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt"><B>Conclusion</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: justify">We urge you to carefully consider the information
contained in this Proxy Statement and then support our efforts by signing, dating, and returning the enclosed <B><U>GOLD</U></B> universal
proxy card or, if applicable, the enclosed <B><U>GOLD</U></B> voting instruction form today to elect the Icahn Nominees.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">Thank you for your support,</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">Icahn Capital LP</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">April 27, 2023</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="background-color: white"><B>FORWARD LOOKING
STATEMENTS</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><FONT STYLE="background-color: white">This Proxy Statement
may include forward-looking statements that reflect the Participants&rsquo; current views with respect to future events, trends, plans
or objectives. Statements that include the words &ldquo;anticipate,&rdquo; &ldquo;believe,&rdquo; &ldquo;estimate,&rdquo; &ldquo;expect,&rdquo;
&ldquo;forecast,&rdquo; &ldquo;intend,&rdquo; &ldquo;may,&rdquo; &ldquo;objective,&rdquo; &ldquo;plan,&rdquo; &ldquo;position,&rdquo;
&ldquo;project,&rdquo; &ldquo;should,&rdquo; &ldquo;strategy,&rdquo; &ldquo;will,&rdquo; &ldquo;would&rdquo; or the negative of those
terms or other variations of them or comparable terminology are often used to identify forward-looking statements. All forward-looking
statements address matters that involve risks and uncertainties, many of which are beyond our control. Accordingly, there are or will
be important factors that could cause actual results to differ materially from those indicated in such statements and, therefore, you
should not place undue reliance on any such statements. Any forward-looking statements made in this Proxy Statement are qualified in their
entirety by these cautionary statements, and there can be no assurance that the actual results or developments anticipated by the Participants
will be realized or, even if substantially realized, that they will have the expected consequences to, or effects on, the Company or its
business, operations or financial condition. Except to the extent required by applicable law, the Participants undertake no obligation
to update publicly or revise any forward-looking statement, whether as a result of new information, future developments or otherwise.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; background-color: white">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B><U>Annex
I: Information REGARDING the Participants</U></B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">This proxy solicitation is being made by the Participants.
The Participants filing this Proxy Statement include <FONT STYLE="background-color: white">Icahn Partners LP (&ldquo;<U>Icahn Partners</U>&rdquo;),
Icahn Onshore LP (&ldquo;<U>Icahn Onshore</U>&rdquo;), Icahn Partners Master Fund LP (&ldquo;<U>Icahn Master</U>&rdquo;), Icahn Offshore
LP (&ldquo;<U>Icahn Offshore</U>&rdquo;), Icahn Capital LP (&ldquo;<U>Icahn Capital</U>&rdquo;), IPH GP LLC (&ldquo;<U>IPH</U>&rdquo;),
Icahn Enterprises Holdings L.P. (&ldquo;<U>Icahn Enterprises Holdings</U>&rdquo;), Icahn Enterprises G.P. Inc. (&ldquo;<U>Icahn Enterprises
GP</U>&rdquo;), Beckton Corp. (&ldquo;<U>Beckton</U>&rdquo;), Matsumura Fishworks LLC, an Ohio limited liability company (&ldquo;<U>Matsumura</U>&rdquo;),
and Carl C. Icahn, a citizen of the United States of America, and each of the following individuals: Mr. Vincent J. Intrieri, Mr.&nbsp;Jesse&nbsp;A.
Lynn, and Mr.&nbsp;Andrew&nbsp;J. Teno, each of whom is a citizen of the United States of America. Mr. Vincent J. Intrieri, Mr.&nbsp;Jesse&nbsp;A.
Lynn, and Mr.&nbsp;Andrew&nbsp;J. Teno are collectively referred to as the &ldquo;<U>Icahn Nominees</U>&rdquo;.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Icahn Partners, Icahn Onshore, Icahn Master, Icahn
Offshore, Icahn Capital, IPH, Icahn Enterprises Holdings, Icahn Enterprises GP, Beckton, <FONT STYLE="background-color: white">Matsumura,
</FONT>and Mr. Icahn are collectively referred to as the &ldquo;<U>Icahn Participants</U>.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white">The
principal business address of Mr.&nbsp;Icahn, Icahn Partners, Icahn Onshore, Icahn Master, Icahn Offshore, Icahn Capital, IPH, Icahn Enterprises
Holdings, Icahn Enterprises GP, Beckton, Mr.&nbsp;Lynn and Mr.&nbsp;Teno is c/o Icahn Enterprises L.P., 16690&nbsp;Collins&nbsp;Ave.,&nbsp;PH-1,&nbsp;Sunny&nbsp;Isles&nbsp;Beach,
FL 33160. The principal business address of Mr. Intrieri is set forth in the Proxy Statement. </FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">Icahn Onshore is the general
partner of Icahn Partners. Icahn Offshore is the general partner of Icahn Master. Icahn Capital is the general partner of each of Icahn
Onshore and Icahn Offshore. Icahn Enterprises Holdings is the sole member of IPH, which is the general partner of Icahn Capital. Beckton
is the sole stockholder of Icahn Enterprises GP, which is the general partner of Icahn Enterprises Holdings. Matsumura is a wholly owned
subsidiary of Icahn Partners. Carl C. Icahn is the sole stockholder of Beckton. As such, Mr. Icahn is in a position indirectly to determine
the investment and voting decisions made by each of Icahn Partners, Icahn Onshore, Icahn Master, Icahn Offshore, Icahn Capital, IPH, Icahn
Enterprises Holdings, Icahn Enterprises GP, Beckton and Matsumura. In addition, Mr. Icahn is the indirect holder of approximately 86%
of the outstanding depositary units representing limited partnership interests in Icahn Enterprises L.P., a Delaware limited partnership
(&ldquo;<U>Icahn Enterprises</U>&rdquo;). Icahn Enterprises GP is the general partner of Icahn Enterprises, which is the sole limited
partner of Icahn Enterprises Holdings.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Each of Matsumura,
Icahn Partners and Icahn Master is primarily engaged in the business of investing in securities. Icahn Onshore is primarily engaged in
the business of serving as the general partner of Icahn Partners. Icahn Offshore is primarily engaged in the business of serving as the
general partner of Icahn Master. Icahn Capital is primarily engaged in the business of serving as the general partner of each of Icahn
Onshore and Icahn Offshore. IPH is primarily engaged in the business of serving as the general partner of Icahn Capital. Icahn Enterprises
Holdings is primarily engaged in the business of holding direct or indirect interests in various operating businesses. Icahn Enterprises
GP is primarily engaged in the business of serving as the general partner of each of Icahn Enterprises and Icahn Enterprises Holdings.
Beckton is primarily engaged in the business of holding the capital stock of Icahn Enterprises GP.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Mr. Icahn&rsquo;s
present principal occupation or employment is serving as (i) Chief Executive Officer of Icahn Capital, a wholly owned subsidiary of Icahn
Enterprises, through which Mr. Icahn manages various private investment funds, including Icahn Partners and Icahn Master, (ii) Chairman
of the Board of Icahn Enterprises GP, the general partner of Icahn Enterprises, a Nasdaq listed diversified holding company engaged in
a variety of businesses, including investment, energy, automotive, food packaging, real estate, home fashion and pharma, and (iii) Chairman
of the Board and a director of Starfire Holding Corporation (&ldquo;<U>Starfire</U>&rdquo;), a holding company engaged in the business
of investing in and/or holding securities of various entities, and as Chairman of the Board and a director of various of Starfire&rsquo;s
subsidiaries.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">As of the Record Date,
the Beneficial Owners beneficially own, in the aggregate, 2,198,853 Shares (including Shares underlying Forwards), representing approximately
1.4% of the Company&rsquo;s Shares (based upon 158,032,030 Shares stated to be outstanding as of the Record Date by the Company in proxy
statement). Except to the extent of any pecuniary interest therein, the other Participants are not entitled to the right to the dividends
on the Shares.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">In addition to Icahn
Partners, Icahn Onshore, Icahn Master, Icahn Offshore, Icahn Capital, IPH, Icahn Enterprises Holdings, Icahn Enterprises GP, Beckton,
Matsumura, and Mr. Icahn, the participants in the solicitation of proxies (the &ldquo;<U>Participants</U>&rdquo;) from stockholders of
Illumina may also include <FONT STYLE="background-color: white">Mr. Vincent J. Intrieri, Mr.&nbsp;Jesse&nbsp;A. Lynn, and</FONT></P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">Mr.&nbsp;Andrew&nbsp;J.
Teno. None of the Icahn Nominees will receive any special compensation in connection with this solicitation.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">In addition, the Participants
may also include Brett Icahn, Andrew Teno and Jesse A. Lynn, each of whom is employed, and therefore compensated, by Icahn Enterprises
or its affiliates. These individuals do not beneficially own any Shares. From time to time, these individuals have served on boards of
directors of entities in which Icahn Enterprises or its affiliates have an interest. In such situations where Icahn Enterprises does not
control such entities, these individuals receive customary director compensation from such entities (which may include cash fees, equity
awards, reimbursement of travel expenses, indemnification and the like). Pursuant to the limited partnership agreement of Icahn Enterprises
(filed as Exhibit 3.1 to Icahn&nbsp;Enterprises&rsquo;&nbsp;Form&nbsp;10-Q&nbsp;for&nbsp;the&nbsp;quarterly period ended June&nbsp;30,
2016, filed with the SEC on August&nbsp;4, 2016), these individuals are entitled to indemnification for certain losses and expenses incurred
in connection with proxy contests and service as directors on boards of directors of companies in which Icahn Enterprises or its affiliates
have an interest (including the proxy contest relating to the Annual Meeting of the Company&rsquo;s stockholders and any service as a
director on the Company&rsquo;s Board). Each of Messrs. Icahn, Teno and Lynn are party to employment agreements with Icahn Enterprises
or its affiliates. Pursuant to the employment agreements with Messrs. Icahn and Teno, under certain circumstances, they will be eligible
to receive certain profit sharing payments relating to net investment gains over a specified hurdle for certain investments held by affiliates
of Icahn Capital (which such investments include the Shares). These individuals will not otherwise receive any special compensation in
connection with the solicitation of proxies from stockholders of the Company.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">As of the Record Date,
Icahn Master has sole voting and sole dispositive power with regard to 915,347 Shares (including Shares underlying Forwards). As of the
Record Date, each of Icahn Offshore, Icahn Capital, IPH GP, Icahn Enterprises Holdings, Icahn Enterprises GP, Beckton and Mr. Icahn, by
virtue of their relationships to Icahn Master, has shared voting power and shared dispositive power with regard to such Shares. Icahn
Partners has sole voting and sole dispositive power with regard to 1,283,406 Shares (including Shares underlying Forwards). Each of Icahn
Onshore, Icahn Capital, IPH GP, Icahn Enterprises Holdings, Icahn Enterprises GP, Beckton and Mr. Icahn, by virtue of their relationships
to Icahn Partners, has shared voting power and shared dispositive power with regard to such Shares. As of the Record Date, Matsumura has
sole voting power and sole dispositive power and shared voting power and shared dispositive power with respect to 100 Shares. Each of
Icahn Onshore, Icahn Capital, IPH GP, Icahn Enterprises Holdings, Icahn Enterprises GP, Beckton and Mr. Icahn, by virtue of their relationships
to Matsumura, has shared voting power and shared dispositive power with regard to such Shares.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">None of the Icahn Nominees own any Shares of Illumina
beneficially or of record. None of the Icahn Nominees has effected any transactions in the securities of Illumina during the past two
years.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Except as set forth in this Proxy Statement (including
the Annexes), (i) during the past ten years, no Participant has been convicted in a criminal proceeding (excluding traffic violations
or similar misdemeanors); (ii) no Participant directly or indirectly beneficially owns any securities of the Company; (iii) no Participant
owns any securities of the Company which are owned of record but not beneficially; (iv) no Participant has purchased or sold any securities
of the Company during the past two years; (v) no part of the purchase price or market value of the securities of the Company owned by
any Participant is represented by funds borrowed or otherwise obtained for the purpose of acquiring or holding such securities; (vi) no
Participant is, or within the past year was, a party to any contract, arrangement, or understanding with any person with respect to any
securities of the Company, including, but not limited to, joint ventures, loan or option arrangements, puts or calls, guarantees against
loss or guarantees of profit, division of losses or profits, or the giving or withholding of proxies; (vii) no associate of any Participant
owns beneficially, directly or indirectly, any securities of the Company; (viii)&nbsp;no Participant owns beneficially, directly or indirectly,
any securities of any parent or subsidiary of the Company; (ix) no Participant nor any of their respective associates was a party to any
transaction, or series of similar transactions, since the beginning of the Company&rsquo;s last fiscal year, or is a party to any currently
proposed transaction, or series of similar transactions, to which the Company or any of its subsidiaries was or is to be a party, in which
the amount involved exceeds $120,000; (x) no Participant nor any of their respective associates has any arrangement or understanding with
any person with respect to any future employment by the Company or its affiliates, or with respect to any future transactions to which
the Company or any of its affiliates will or may be a party; and (xi) no person, including the Participants, has a substantial interest,
direct or indirect, by security holdings or otherwise in any matter to be acted on as set forth in this Proxy Statement. There are no
material proceedings to which the Participants or any of their respective associates is a party adverse to the Company or any of its subsidiaries
or has a material interest adverse to the Company or any of its subsidiaries.</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">During the last fiscal
year, neither any Icahn Nominee nor any Icahn Participant has failed to file reports related to the Company that are required by Section&nbsp;16(a)
of the Exchange Act.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">To the best knowledge
of the Participants, the Participants believe that each of the Icahn Nominees is independent under the applicable rules of Nasdaq and
Illumina&rsquo;s corporate governance guidelines.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Except as set forth in this Proxy Statement (including
the Annexes), the Icahn Participants are not the members of a &ldquo;group&rdquo; (as such term is used in Rule 13d-5 of the Exchange
Act) or otherwise acting in concert with any other person.</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>Beneficial Ownership of Shares</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">The following table shows the number of Shares that
are beneficially owned (within the meaning of Rule 13d-3 under the Exchange Act) by each of the Participants in this solicitation as of
the Record Date. Except as described below, each Participant directly owns and has sole voting power and sole dispositive power with regard
to the number of Shares beneficially owned.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 25%; border: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><B>Title of Class</B></TD>
    <TD STYLE="width: 30%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><B>Name of Beneficial Owner </B><SUP>(1)</SUP></TD>
    <TD STYLE="width: 26%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><B>Amount of Beneficial Ownership</B></TD>
    <TD STYLE="width: 19%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><B>Percent of Class </B><SUP>(4)</SUP></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Shares</TD>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Icahn Partners</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 17.1pt; padding-left: 5.4pt; text-align: right">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1,283,506 <SUP>(2)</SUP>&nbsp;<SUP>(3)</SUP>&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right">0.8%</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Shares</TD>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Icahn Master</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 17.1pt; padding-left: 5.4pt; text-align: right">&#9;&nbsp;701,651 <SUP>(2)</SUP>&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right">0.6%</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Shares</TD>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="background-color: white">Icahn Onshore LP </FONT></TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 17.1pt; padding-left: 5.4pt; text-align: right">&nbsp;1,283,506 <SUP>(2)</SUP>&nbsp;<SUP>(3)</SUP>&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right">0.8%</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Shares</TD>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="background-color: white">Icahn Offshore LP </FONT></TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 17.1pt; padding-left: 5.4pt; text-align: right">701,651 <SUP>(2)</SUP>&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right">0.6%</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Shares</TD>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="background-color: white">Icahn Capital LP</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 17.1pt; padding-left: 5.4pt; text-align: right">&nbsp;2,198,853 <SUP>(2)</SUP>&nbsp;<SUP>(3)</SUP>&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right">1.4%</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Shares</TD>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="background-color: white">IPH GP LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 17.1pt; padding-left: 5.4pt; text-align: right">&nbsp;2,198,853<SUP>(2)</SUP>&nbsp;<SUP>(3)</SUP>&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right">1.4%</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Shares</TD>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="background-color: white">Icahn Enterprises Holdings L.P. </FONT></TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 17.1pt; padding-left: 5.4pt; text-align: right">&nbsp;2,198,853<SUP>(2)</SUP>&nbsp;<SUP>(3)</SUP>&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right">1.4%</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Shares</TD>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="background-color: white">Icahn Enterprises G.P. Inc.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 17.1pt; padding-left: 5.4pt; text-align: right">&nbsp;2,198,853<SUP>(2)</SUP>&nbsp;<SUP>(3)</SUP>&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right">1.4%</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Shares</TD>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="background-color: white">Beckton Corp.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 17.1pt; padding-left: 5.4pt; text-align: right">&nbsp;2,198,853<SUP>(2)</SUP>&nbsp;<SUP>(3)</SUP>&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right">1.4%</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Shares</TD>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Matsumura</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 17.1pt; padding-left: 5.4pt; text-align: right">100</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right">Less than 1%</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Shares</TD>
    <TD STYLE="vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">Carl C. Icahn</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 17.1pt; padding-left: 5.4pt; text-align: right">&nbsp;2,198,853<SUP>(2)</SUP>&nbsp;<SUP>(3)</SUP>&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: right">1.4%</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 6pt; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
<TD STYLE="width: 35pt; text-align: right">(1)</TD><TD STYLE="width: 5pt"></TD><TD STYLE="text-align: justify">Each holder listed in this table is, as of the date of this Notice, the direct beneficial
owner of the Shares set forth under the heading &ldquo;Amount of Beneficial Ownership.&rdquo;</TD>
</TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 6pt; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
<TD STYLE="width: 35pt; text-align: right">(2)</TD><TD STYLE="width: 5pt"></TD><TD STYLE="text-align: justify">Includes Shares to be acquired pursuant to forward contracts (&ldquo;<U>Forwards</U>&rdquo;),
which expire on February 13, 2026. An aggregate of 1,768,853 Shares were acquired at a forward price of $170.00 per share, for an aggregate
forward price of approximately $300.7 million, plus a &#64257;nancing charge.</TD>
</TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 6pt; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
<TD STYLE="width: 35pt; text-align: right">(3)</TD><TD STYLE="width: 5pt"></TD><TD STYLE="text-align: justify">Includes 100 Shares that are held of record by Matsumura.</TD>
</TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 6pt; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
<TD STYLE="width: 35pt; text-align: right">(4)</TD><TD STYLE="width: 5pt"></TD><TD STYLE="text-align: justify">Percentages of ownership set forth in this column are based upon 158,032,030 Shares stated
to be outstanding as of the Record Date by the Company in proxy statement.</TD>
</TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt 0.5in; text-indent: -0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt"><B>&nbsp;</B></P>


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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>Two Year Summary Table</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: justify">The table below indicates the date of each purchase
of Shares by the Record Holder and the other Beneficial Owners within the past two years and the number of Shares in each such purchase
(including Shares underlying forward contracts). All such Shares (including Shares underlying forward contracts) were purchased because
the purchaser thereof believed that the Shares represented an attractive investment opportunity. Unless otherwise indicated, all transactions
were effected on the open market. None of the Icahn Nominees have purchased any Shares during the past two years.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD ROWSPAN="2" STYLE="white-space: nowrap; vertical-align: top; width: 33%; border: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt"><B><U>Name of Beneficial Owner</U></B></FONT></TD>
    <TD ROWSPAN="2" STYLE="white-space: nowrap; vertical-align: top; width: 18%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt"><B><U>Date of Transaction</U></B></FONT></TD>
    <TD ROWSPAN="2" STYLE="white-space: nowrap; vertical-align: top; width: 19%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt"><B><U>Number of Securities</U></B></FONT></TD>
    <TD ROWSPAN="2" STYLE="white-space: nowrap; vertical-align: top; width: 18%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt"><B><U>Price Per Share ($)</U></B></FONT></TD>
    <TD STYLE="width: 11%">&nbsp;</TD>
    <TD STYLE="width: 1%">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/13/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;250,937 </FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$208.69 </FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/13/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;112,346 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$44.99 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/14/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;60,611 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$39.89 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/15/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;5,108 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$41.81 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/16/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;130,348 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$41.58 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/17/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;91,042 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$39.78 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/21/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;257,033 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$34.41 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/23/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;76,310 <SUP>(1)</SUP>&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$30.54 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/24/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">72,541 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$27.36</FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/27/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">87,936 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$26.93 </FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/28/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">4,876 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$26.95 </FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">3/1/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">13,912 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$27.35 </FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">3/2/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">1,956 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$27.22 </FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">3/7/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">48,213 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$38.15 </FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">3/8/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">29,396 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$37.76 </FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">3/9/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;40,841 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$34.00 </FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/13/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;178,963 </FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$208.69 </FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/13/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;80,123 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$44.99 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/14/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;43,298 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$39.89 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/15/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;3,643 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$41.81 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/16/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;92,962 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$41.58 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/17/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;64,929 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$39.78 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/21/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;183,309 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$34.41 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/23/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;54,424 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$30.54 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/24/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">51,735 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$27.36 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/27/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">62,714 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$26.93 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/28/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">3,478 <SUP>(1)</SUP>&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$26.95 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">3/1/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">9,900 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$27.35 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">3/2/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">1,395 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$27.22 <SUP>(2)</SUP></FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">3/7/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">34,384 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$38.15 <SUP>(2)</SUP>&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">3/8/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">20,963 <SUP>(1)</SUP></FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$37.76 <SUP>(2)</SUP>&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Icahn Partners Master Fund LP</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">3/9/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">29,127 <SUP>(1)</SUP>&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">$34.00 <SUP>(2)</SUP>&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt"><FONT STYLE="font-size: 10pt">Matsumura Fishworks LLC </FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center"><FONT STYLE="font-size: 10pt">2/13/2023</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.25pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">100</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: top; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 19.5pt; padding-left: 5.4pt; text-align: right"><FONT STYLE="font-size: 10pt">&nbsp;$208.24 </FONT></TD>
    <TD STYLE="padding-right: 5.4pt; padding-left: 5.4pt">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 9pt"></TD><TD STYLE="width: 18pt">(1)</TD><TD STYLE="text-align: justify">Represents Shares to be acquired pursuant to Forwards, which expire on February 13, 2026.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 27pt; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 9pt"></TD><TD STYLE="width: 18pt">(2)</TD><TD STYLE="text-align: justify">Represents the amount per Share paid to the counterparty to the Forward upon entering into such Forwards,
which expire on February 13, 2026. An aggregate of 1,768,853 Shares were acquired at a forward price of $170.00 per share, for an aggregate
forward price of approximately $300.7 million, plus a &#64257;nancing charge.</TD></TR></TABLE>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 27pt; text-align: justify">The forward price is subject to adjustment
to account for any dividends or other distributions declared by the Company. The counterparty to the Forwards was paid an aggregate amount
of approximately $<FONT STYLE="font-size: 10pt">63.6 million upon entering into such Forwards.</FONT></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>


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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>IMPORTANT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Please review this Proxy Statement and the enclosed
materials carefully. YOUR VOTE IS VERY IMPORTANT, no matter how many or how few Shares you own.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; background-color: white; border-collapse: collapse">
  <TR>
    <TD STYLE="width: 4%; text-align: justify">&nbsp;</TD>
    <TD STYLE="vertical-align: top; width: 4%; text-align: justify"><FONT STYLE="font-size: 10pt">1.</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: justify"><FONT STYLE="font-size: 10pt">If your Shares are registered in your own name, please sign, date and mail the enclosed&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy card to <FONT STYLE="background-color: white">HKL &amp; Co., LLC </FONT>in the postage-paid envelope provided today.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; background-color: white; border-collapse: collapse">
  <TR>
    <TD STYLE="width: 4%; text-align: justify">&nbsp;</TD>
    <TD STYLE="vertical-align: top; width: 4%; text-align: justify"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: justify"><FONT STYLE="font-size: 10pt">If you have previously signed and returned a proxy card to the Company, you have every right to change your vote. Only your latest dated proxy card will count. You may revoke any proxy card already sent to the Company by signing, dating and mailing the enclosed&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy card in the postage-paid envelope provided. Any proxy may be revoked at any time prior to the Annual Meeting (i) by delivering a written notice of revocation or a later-dated proxy for the Annual Meeting to <FONT STYLE="background-color: white">HKL &amp; Co., LLC</FONT>, <FONT STYLE="background-color: white">(ii) by delivering a written notice of revocation or a later-dated proxy for the Annual Meeting to the Company or its proxy solicitor, or </FONT>(iii) by voting at the Annual Meeting. Attendance at the Annual Meeting will not in and of itself constitute a revocation.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; background-color: white; border-collapse: collapse">
  <TR>
    <TD STYLE="width: 4%; text-align: justify">&nbsp;</TD>
    <TD STYLE="vertical-align: top; width: 4%; text-align: justify"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD STYLE="vertical-align: top; text-align: justify"><FONT STYLE="font-size: 10pt">If your Shares are held in the name of a bank, brokerage firm, dealer, trust company or other custodian, only such firm, custodian or other institution can vote your Shares and only after receiving your specific instructions by mail or via the Internet. Accordingly, please sign, date and mail the enclosed&nbsp;<B><U>GOLD</U></B>&nbsp;voting instruction form in the postage-paid envelope provided or via the Internet by following the instructions provided by your custodian broker or bank, and to ensure that your Shares are voted, you should also contact the person responsible for your account and give instructions for a&nbsp;<B><U>GOLD</U></B>&nbsp;universal proxy card to be issued representing your Shares.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; background-color: white; border-collapse: collapse">
  <TR>
    <TD STYLE="width: 4%; text-align: justify">&nbsp;</TD>
    <TD STYLE="vertical-align: top; width: 4%; text-align: justify"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">After signing and returning the enclosed&nbsp;<B><U>GOLD</U></B>&nbsp;universal
    proxy card or, if applicable, the <B><U>GOLD</U></B> voting instruction form, do not sign or return the Company&rsquo;s white proxy card
    or, if applicable, voting instruction form unless you intend to change your vote, because only your latest dated proxy card will be counted.</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>IF YOU ARE A STOCKHOLDER OF RECORD AND ALREADY
HAVE VOTED USING THE COMPANY&rsquo;S WHITE PROXY CARD OR VIA THE INTERNET BY FOLLOWING THE INSTRUCTIONS PROVIDED TO YOU BY THE COMPANY,
YOU MAY REVOKE YOUR PREVIOUSLY SUBMITTED WHITE PROXY BY SIGNING AND RETURNING A LATER-DATED&nbsp;<U>GOLD</U> UNIVERSAL PROXY CARD USING
THE ENCLOSED POSTAGE-PAID ENVELOPE, OR BY DELIVERING A WRITTEN NOTICE OF REVOCATION TO THE COMPANY OR TO THE SECRETARY OF THE COMPANY.
ONLY THE LATEST VALIDLY EXECUTED PROXY THAT YOU SUBMIT WILL BE COUNTED.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>IF YOU ARE A STREET-NAME HOLDER (I.E., IF YOUR
SHARES ARE HELD FOR YOU BY A CUSTODIAN BROKER OR BANK) AND IF YOU ALREADY HAVE PROVIDED YOUR BROKER OR BANK CUSTODIAN WITH VOTING INSTRUCTIONS
USING THE COMPANY&rsquo;S WHITE VOTING INSTRUCTION FORM OR VIA THE INTERNET, YOU MAY REVOKE YOUR PREVIOUSLY SUBMITTED VOTING INSTRUCTIONS
BY SIGNING AND SUBMITTING A LATER-DATED <U>GOLD</U> UNIVERSAL VOTING INSTRUCTION FORM USING THE POSTAGE-PAID ENVELOPE PROVIDED BY YOUR
CUSTODIAN BROKER OR BANK OR VIA THE INTERNET BY FOLLOWING THE INSTRUCTIONS PROVIDED BY YOUR CUSTODIAN BROKER OR BANK. IN THAT CASE, YOUR
CUSTODIAN BROKER OR BANK WILL SEEK TO GIVE EFFECT TO ONLY THE LATEST-DATED VOTING INSTRUCTIONS IT RECEIVES FROM YOU.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><I>&nbsp;</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><I>If you have any questions concerning this Proxy
Statement, would like to request additional copies of this Proxy Statement, or need help voting your Shares, please contact our proxy
solicitor:</I></P>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<DIV STYLE="margin-right: 2.15pt; margin-left: 2.15pt; padding: 0in; border: black 1.5pt solid">

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: center"><B>&nbsp; </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0 0; text-align: center"><FONT STYLE="background-color: white"><B>HKL
&amp; Co., LLC</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>3 Columbus Circle, 15<SUP>th</SUP> Floor</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>New York, NY 10019</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Banks and Brokerage Firms Please Call Collect: +1
(212) 468-5380 </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>All Others Call Toll-Free: +1 (800) 257-3995</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt; text-align: center"><B>Email: ILMN@hklco.com</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt"><B>&nbsp;</B></P>

</DIV>



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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="background-color: white">[GOLD
UNIVERSAL PROXY CARD]</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>ILLUMINA, INC. </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>2023 ANNUAL MEETING OF STOCKHOLDERS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify; background-color: white"><B>THIS PROXY (THIS &ldquo;<U>PROXY</U>&rdquo;)
IS SOLICITED ON BEHALF <FONT STYLE="font-family: Times New Roman, Times, Serif; text-transform: uppercase">OF ICAHN PARTNERS LP, ICAHN
PARTNERS MASTER FUND LP, ICAHN ONSHORE LP, ICAHN OFFSHORE LP, ICAHN CAPITAL LP, IPH GP LLC, ICAHN ENTERPRISES HOLDINGS L.P., icahn enterprises
g.p. inc., beckton corp., MATSUMURA FISHWORKS LLC, carl c. icahn, VINCENT J. INTRIERI, </FONT>JESSE A. LYNN, AND ANDREW J. TENO <FONT STYLE="font-family: Times New Roman, Times, Serif; text-transform: uppercase">(Collectively,
the &ldquo;<U>participants</U>&rdquo;)</FONT></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; background-color: white"><FONT STYLE="text-transform: uppercase"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; background-color: white"><FONT STYLE="text-transform: uppercase"><B>THIS
PROXY SOLICITATION IS NOT BEING MADE BY OR ON BEHALF OF<BR>
ILLUMINA, INC. </B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">The undersigned appoint(s)
Peter C. Harkins and Jordan M. Kovler and each of them, as proxies (each and any substitute, a &ldquo;<U>Proxyholder</U>&rdquo;) with
full power of substitution and with discretionary authority to vote all shares of common stock, par value $0.01 per share (the &ldquo;<U>Shares</U>&rdquo;),
of Illumina, Inc. (the &ldquo;<U>Company</U>&rdquo;), which the undersigned would be entitled to vote if present at the 2023 Annual Meeting
of Stockholders of the Company scheduled to be held virtually on May 25, 2023 at 10:00 a.m. (Pacific time), including any adjournments,
continuations or postponements thereof and at any meeting called in lieu thereof (the &ldquo;<U>Annual Meeting</U>&rdquo;) on all matters
coming before the Annual Meeting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">The undersigned hereby
revokes any other proxy or proxies heretofore given to vote or act with respect to the Shares of the Company held by the undersigned,
and hereby ratifies and confirms all actions the herein named Proxyholders, their substitutes, or any of them may lawfully take by virtue
hereof. Other than the five (5) proposals set forth on the reverse side of this card, the Participants are not aware of any other matters
to be considered at the Annual Meeting. However, should other matters, unknown a reasonable time before the Annual Meeting, be brought
before the Annual Meeting, each Proxyholder will vote on such matters in their discretion. If properly executed, this Proxy will be voted
as directed on the reverse side and each Proxyholder will vote in his or her discretion with respect to any other matters, unknown a reasonable
time before the Annual Meeting, as may properly come before the Annual Meeting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white">This Proxy will be
valid until the completion of the Annual Meeting. This Proxy will only be valid in connection with the Participants&rsquo; solicitation
of proxies for the Annual Meeting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white"><B>IF
THIS PROXY IS SIGNED AND RETURNED, IT WILL BE VOTED IN ACCORDANCE WITH YOUR SPECIFICATIONS AND AS DETAILED BELOW, AS APPLICABLE. </B></FONT><B>IF
NO DIRECTION IS INDICATED WITH RESPECT TO THE PROPOSALS ON THE REVERSE SIDE, THIS&nbsp;PROXY WILL BE VOTED (1) <FONT STYLE="background-color: white">&ldquo;<U>FOR</U>&rdquo;
EACH OF THE ICAHN NOMINEES, TO &ldquo;<U>WITHHOLD</U>&rdquo; ON EACH OF THE OPPOSED COMPANY NOMINEES AND EACH OF THE ACCEPTABLE COMPANY
NOMINEES, </FONT>(2) &ldquo;<U>FOR</U>&rdquo; THE RATIFICATION OF THE APPOINTMENT OF ERNST &amp; YOUNG LLP AS THE COMPANY&rsquo;S INDEPENDENT
REGISTERED PUBLIC ACCOUNTING FIRM FOR THE FISCAL YEAR ENDING DECEMBER 31, 2023; (3) &ldquo;<U>AGAINST</U>&rdquo; THE APPROVAL, ON AN ADVISORY
BASIS, OF THE COMPENSATION OF THE &ldquo;NAMED EXECUTIVE OFFICERS&rdquo; AS DISCLOSED IN THE COMPANY&rsquo;S PROXY STATEMENT; (4) &ldquo;<U>1
YEAR</U>&rdquo; ON THE PROPOSAL TO APPROVE, ON AN ADVISORY BASIS, THE FREQUENCY OF HOLDING AN ADVISORY VOTE TO APPROVE THE COMPENSATION
PROVIDED TO THE COMPANY&rsquo;S &ldquo;NAMED EXECUTIVE OFFICERS&rdquo;; (5) &ldquo;<U>ABSTAIN</U>&rdquo; ON THE APPROVAL OF THE AMENDMENTS
TO THE ILLUMINA, INC. 2015 STOCK AND INCENTIVE PLAN; AND (6) <FONT STYLE="background-color: white">IN THE PROXY HOLDERS&rsquo; DISCRETION
AS TO OTHER MATTERS THAT MAY PROPERLY COME BEFORE THE ANNUAL MEETING.</FONT></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white"><B>YOU
MAY VOTE &ldquo;FOR&rdquo; UP TO NINE (9) NOMINEES IN TOTAL: </B></FONT></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 12pt; margin-bottom: 0; background-color: white"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="background-color: white"><B>IF YOU VOTE ON AT LEAST ONE NOMINEE BUT FEWER THAN NINE (9) NOMINEES
IN PROPOSAL 1, YOUR SHARES WILL BE VOTED &ldquo;FOR&rdquo; ONLY THOSE NOMINEES YOU HAVE SO MARKED.</B></FONT></TD></TR></TABLE>


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<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 12pt; margin-bottom: 0; background-color: white"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="background-color: white"><B>IF YOU VOTE &ldquo;FOR&rdquo; MORE THAN NINE (9) NOMINEES ON
A <U>GOLD</U> UNIVERSAL PROXY CARD, YOUR VOTES ON PROPOSAL 1 REGARDING THE NOMINEES WILL BE INVALID AND WILL NOT BE COUNTED.</B></FONT></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center; background-color: white">IMPORTANT: PLEASE COMPLETE,
SIGN, DATE AND MAIL THIS <B><U>GOLD</U></B> UNIVERSAL PROXY CARD TODAY!</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><B>PROPOSAL 1</B>:
Election of nine (9) directors of Illumina for a term to end as of the 2024 annual meeting and until their successors are duly elected
and qualified.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><B><I>Vote &ldquo;FOR&rdquo;
up to nine (9) nominees in total</I></B><I>.&nbsp;&nbsp;If you vote this&nbsp;<U>GOLD</U>&nbsp;universal proxy card for less than nine
(9) nominees, your shares will be voted &ldquo;FOR&rdquo; only those nominees you have marked.&nbsp;If you vote this&nbsp;<U>GOLD</U>&nbsp;universal
proxy card &ldquo;FOR&rdquo; more than nine (9) nominees, your votes on Proposal 1 regarding the nominees will be invalid and will not
be counted.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: center"><B>INSTRUCTIONS: FILL IN VOTING BOXES &ldquo;<IMG SRC="filled_ballot.jpg" ALT="" STYLE="height: 5.25pt; width: 5.25pt">&ldquo;
IN BLACK OR BLUE INK</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt"><FONT STYLE="text-transform: uppercase"><B>We recommend THAT YOU
vote &ldquo;<U>FOR</U>&rdquo; each of the Icahn Nominees.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt"><B><U><BR></U></B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 0pt; text-align: left; width: 35%"><FONT STYLE="font-size: 10pt"><B><U>ICAHN NOMINEES</U></B></FONT></TD>
    <TD STYLE="padding-top: 0pt; text-align: left; width: 32%"><FONT STYLE="font-size: 10pt"><B>FOR</B></FONT></TD>
    <TD STYLE="padding-top: 0pt; text-align: left; width: 33%"><FONT STYLE="font-size: 10pt"><B>WITHHOLD</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">Vincent J. Intrieri</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">Jesse A. Lynn </FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">Andrew J. Teno </FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt"><FONT STYLE="text-transform: uppercase"><B><BR>
We MAKE NO RECOMMENDATION ON THE ACCEPTABLE COMPANY NOMINEES.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><B></B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 0pt; width: 35%; text-align: left"><FONT STYLE="font-size: 10pt"><B><U>ACCEPTABLE COMPANY NOMINEES</U></B></FONT></TD>
    <TD STYLE="padding-top: 0pt; width: 32%; text-align: left"><FONT STYLE="font-size: 10pt"><B>FOR</B></FONT></TD>
    <TD STYLE="padding-top: 0pt; width: 33%; text-align: left"><FONT STYLE="font-size: 10pt"><B>WITHHOLD</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">Frances Arnold</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">Caroline D. Dorsa</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">Scott Gottlieb</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">Gary S. Guthart</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">Philip W. Schiller </FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">Susan E. Siegel</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt"><FONT STYLE="text-transform: uppercase"><B>We recommend THAT YOU
&ldquo;<U>WITHHOLD</U>&rdquo; ON EACH OF Francis A. deSouza, Robert S. Epstein AND John W. Thompson.</B></FONT></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 0pt; width: 35%; text-align: left"><FONT STYLE="font-size: 10pt"><B><U>OPPOSED COMPANY NOMINEES</U></B></FONT></TD>
    <TD STYLE="padding-top: 0pt; width: 32%; text-align: left"><FONT STYLE="font-size: 10pt"><B>FOR</B></FONT></TD>
    <TD STYLE="padding-top: 0pt; width: 33%; text-align: left"><FONT STYLE="font-size: 10pt"><B>WITHHOLD</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">Francis A. deSouza</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">Robert S. Epstein </FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-size: 10pt">John W. Thompson</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="padding-top: 10pt; text-align: left"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  </TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 6pt"><FONT STYLE="text-transform: uppercase"><B>&nbsp;</B></FONT></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><B>PROPOSAL 2</B>:
To ratify the appointment of Ernst &amp; Young LLP as Illumina&rsquo;s independent registered public accounting firm for the fiscal year
ending December 31, 2023.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><B>WE RECOMMEND THAT
YOU VOTE &ldquo;<U>FOR</U>&rdquo; THE RATIFICATION OF THE APPOINTMENT OF ERNST &amp; YOUNG LLP AS THE COMPANY&rsquo;S INDEPENDENT REGISTERED
PUBLIC ACCOUNTING FIRM FOR THE FISCAL YEAR ENDING DECEMBER 31, 2023.</B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="vertical-align: bottom; width: 34%; text-align: center"><FONT STYLE="font-size: 10pt"><B>FOR</B></FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 33%; text-align: center"><FONT STYLE="font-size: 10pt"><B>AGAINST</B></FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 33%; text-align: center">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>ABSTAIN</B></P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>PROPOSAL 3</B>: <FONT STYLE="background-color: white">&thinsp;&thinsp;To
approve, on an advisory basis, the compensation of the &ldquo;named executive officers&rdquo; as disclosed in the Company&rsquo;s Proxy
Statement.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><B>WE RECOMMEND THAT
YOU VOTE &ldquo;<U>AGAINST</U>&rdquo; THE APPROVAL, ON AN ADVISORY BASIS, OF THE COMPENSATION OF THE &ldquo;NAMED EXECUTIVE OFFICERS&rdquo;
AS DISCLOSED IN THE COMPANY&rsquo;S PROXY STATEMENT.</B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="vertical-align: bottom; width: 34%; text-align: center"><FONT STYLE="font-size: 10pt"><B>FOR</B></FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 33%; text-align: center"><FONT STYLE="font-size: 10pt"><B>AGAINST</B></FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 33%; text-align: center">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>ABSTAIN</B></P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><B>PROPOSAL 4</B>:
<FONT STYLE="background-color: white">&thinsp;&thinsp;To approve, on an advisory basis, the frequency of holding an advisory vote to approve
the compensation provided to the Company&rsquo;s &ldquo;named executive officers&rdquo;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><B>WE RECOMMEND THAT
YOU VOTE &ldquo;<U>1 YEAR</U>&rdquo; ON THE PROPOSAL TO APPROVE, ON AN ADVISORY BASIS, THE FREQUENCY OF HOLDING AN ADVISORY VOTE TO APPROVE
THE COMPENSATION PROVIDED TO THE COMPANY&rsquo;S &ldquo;NAMED EXECUTIVE OFFICERS&rdquo;</B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 25%">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center"><B>1 YEAR</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center">&#9744;</P></TD>
    <TD STYLE="width: 25%">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center"><B>2 YEARS</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center">&#9744;</P></TD>
    <TD STYLE="width: 25%">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center"><B>3 YEARS</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center">&#9744;</P></TD>
    <TD STYLE="width: 25%">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center"><B>ABSTAIN</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center">&#9744;</P></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><B>PROPOSAL 5</B>:
<FONT STYLE="background-color: white">&thinsp;&thinsp;To approve certain amendments to the Illumina, Inc. 2015 Stock and Incentive Plan.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: justify; background-color: white"><B>WE MAKE NO RECOMMENDATION
ON THE APPROVAL OF THE AMENDMENTS TO THE ILLUMINA, INC. 2015 STOCK AND INCENTIVE PLAN.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="vertical-align: bottom; width: 34%; font-size: 10pt; text-align: center"><FONT STYLE="font-size: 10pt"><B>FOR</B></FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 33%; font-size: 10pt; text-align: center"><FONT STYLE="font-size: 10pt"><B>AGAINST</B></FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 33%; text-align: center">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>ABSTAIN</B></P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></P>

<!-- Field: Page; Sequence: 44 -->
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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>IN ORDER FOR YOUR PROXY TO BE VALID, IT MUST BE
SIGNED. PLEASE ALSO DATE THE PROXY WHERE INDICATED BELOW.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="border-bottom: black 1pt solid; vertical-align: top; width: 68%; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; width: 8%; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="border-bottom: black 1pt solid; vertical-align: bottom; width: 24%; font-size: 10pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-size: 10pt">Signature (Capacity/Title)</FONT></TD>
    <TD STYLE="vertical-align: top; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-size: 10pt">Date</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P></TD>
    <TD STYLE="vertical-align: top; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="border-bottom: black 1pt solid; vertical-align: top; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="border-bottom: black 1pt solid; vertical-align: bottom; font-size: 10pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;Signature (Joint Owner) (Capacity/Title)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P></TD>
    <TD STYLE="vertical-align: top; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Date</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="3">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>&nbsp;</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B>NOTE: </B>Please sign exactly as your name(s) appear(s)
    on stock certificates or on the label affixed hereto. When signing as attorney, executor, administrator or other fiduciary, please give
    full title as such. Joint owners should each sign personally. <B>ALL HOLDERS MUST SIGN.</B> If a corporation or partnership, please sign
    in full corporate or partnership name by an authorized officer and give full title as such.</P></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>PLEASE <U>SIGN</U>, <U>DATE</U> AND <U>PROMPTLY
RETURN</U> THIS <FONT STYLE="background-color: white">GOLD UNIVERSAL PROXY CARD</FONT> USING THE ENCLOSED RETURN ENVELOPE.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 8pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"></P>


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end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
