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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Millions
 9 Months Ended
Sep. 29, 2024
Oct. 01, 2023
Cash flows from operating activities:    
Net income (loss) $ (1,410) $ (986)
Adjustments to reconcile net loss to net cash provided by operating activities:    
Depreciation expense 170 175
Amortization of intangible assets 113 148
Share-based compensation expense 291 286
Deferred income taxes (161) (42)
Goodwill and intangible (IPR&D) impairment 1,889 821
Property and equipment and right-of-use asset impairment 32 56
Net losses on strategic investments 342 39
Gain on Helix contingent value right (15) (8)
Change in fair value of contingent consideration liabilities (304) (82)
Other 11 15
Changes in operating assets and liabilities:    
Accounts receivable 20 (31)
Inventory (9) (47)
Prepaid expenses and other current assets (11) (3)
Operating lease right-of-use assets and liabilities, net (21) (13)
Other assets (14) 6
Accounts payable (35) (50)
Accrued liabilities (406) (25)
Other long-term liabilities (9) (5)
Net cash provided by operating activities 473 254
Cash flows from investing activities:    
Purchases of property and equipment (99) (144)
Net purchases of strategic investments (33) (1)
Cash received for Helix contingent value right 83 0
Cash paid for acquisitions and intangible assets, net of cash acquired (81) (1)
Net cash used in investing activities (130) (146)
Cash flows from financing activities:    
GRAIL cash deconsolidated as a result of spin-off (968) 0
Proceeds from debt, net of issuance costs 1,241  
Proceeds from debt, net of issuance costs   (1)
Payments on debt obligations (750) (1,235)
Payments on contingent consideration liabilities (1) 0
Common stock repurchases (99) 0
Taxes paid related to net share settlement of equity awards (2) (14)
Proceeds from issuance of common stock 56 67
Net cash used in financing activities (523) (1,183)
Effect of exchange rate changes on cash and cash equivalents 1 (9)
Net decrease in cash and cash equivalents (179) (1,084)
Cash and cash equivalents at beginning of period 1,048 2,011
Cash and cash equivalents at end of period 869 927
Supplemental cash flow information:    
GRAIL net assets, excluding cash and cash equivalents, deconsolidated as a result of spin-off $ 1,770 $ 0