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REVENUE - Disaggregation of Revenue (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 29, 2024	Oct. 01, 2023	Sep. 29, 2024	Oct. 01, 2023
Disaggregation of Revenue [Line Items]
Consolidated revenue	$ 1,080	$ 1,119	$ 3,268	$ 3,382
Americas
Disaggregation of Revenue [Line Items]
Consolidated revenue	609	663	1,852	1,920
Europe
Disaggregation of Revenue [Line Items]
Consolidated revenue	291	260	859	825
Greater China
Disaggregation of Revenue [Line Items]
Consolidated revenue	75	98	228	302
Asia-Pacific, Middle East, and Africa
Disaggregation of Revenue [Line Items]
Consolidated revenue	105	98	329	335
Total product revenue
Disaggregation of Revenue [Line Items]
Consolidated revenue	914	941	2,718	2,864
Consumables
Disaggregation of Revenue [Line Items]
Consolidated revenue	807	760	2,376	2,327
Instruments
Disaggregation of Revenue [Line Items]
Consolidated revenue	107	181	342	537
Service and other revenue
Disaggregation of Revenue [Line Items]
Consolidated revenue	166	178	550	518
Sequencing
Disaggregation of Revenue [Line Items]
Consolidated revenue	995	1,029	2,989	3,088
Sequencing | Total product revenue
Disaggregation of Revenue [Line Items]
Consolidated revenue	845	867	2,490	2,632
Sequencing | Consumables
Disaggregation of Revenue [Line Items]
Consolidated revenue	741	689	2,160	2,108
Sequencing | Instruments
Disaggregation of Revenue [Line Items]
Consolidated revenue	104	178	330	524
Sequencing | Service and other revenue
Disaggregation of Revenue [Line Items]
Consolidated revenue	150	162	499	456
Microarray
Disaggregation of Revenue [Line Items]
Consolidated revenue	85	90	279	294
Microarray | Total product revenue
Disaggregation of Revenue [Line Items]
Consolidated revenue	69	74	228	232
Microarray | Consumables
Disaggregation of Revenue [Line Items]
Consolidated revenue	66	71	216	219
Microarray | Instruments
Disaggregation of Revenue [Line Items]
Consolidated revenue	3	3	12	13
Microarray | Service and other revenue
Disaggregation of Revenue [Line Items]
Consolidated revenue	$ 16	$ 16	$ 51	$ 62

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