<SEC-DOCUMENT>0001127602-24-013333.txt : 20240424
<SEC-HEADER>0001127602-24-013333.hdr.sgml : 20240424
<ACCEPTANCE-DATETIME>20240424170430
ACCESSION NUMBER:		0001127602-24-013333
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20240415
FILED AS OF DATE:		20240424
DATE AS OF CHANGE:		20240424

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Wedel Christensen Jakob
		CENTRAL INDEX KEY:			0002020721
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-35406
		FILM NUMBER:		24871432

	MAIL ADDRESS:	
		STREET 1:		5200 ILLUMINA WAY
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92122

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ILLUMINA, INC.
		CENTRAL INDEX KEY:			0001110803
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		IRS NUMBER:				330804655
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1229

	BUSINESS ADDRESS:	
		STREET 1:		5200 ILLUMINA WAY
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92122
		BUSINESS PHONE:		8582024500

	MAIL ADDRESS:	
		STREET 1:		5200 ILLUMINA WAY
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92122

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ILLUMINA INC
		DATE OF NAME CHANGE:	20000331
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>form3.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2024-04-15</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001110803</issuerCik>
        <issuerName>ILLUMINA, INC.</issuerName>
        <issuerTradingSymbol>ILMN</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0002020721</rptOwnerCik>
            <rptOwnerName>Wedel Christensen Jakob</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5200 ILLUMINA WAY</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>SAN DIEGO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92122</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>1</isOfficer>
            <officerTitle>SVP, Strategy/Corp Development</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3356</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Performance Shares</value>
                <footnoteId id="F2"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F3"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F3"/>
            </exerciseDate>
            <expirationDate>
                <value>2027-01-03</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>1393</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Performance Shares</value>
                <footnoteId id="F2"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F4"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F4"/>
            </exerciseDate>
            <expirationDate>
                <value>2027-01-03</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>1393</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Includes unvested Restricted Stock Units granted prior to appointment as Section 16 Officer.</footnote>
        <footnote id="F2">Granted prior to appointment as Section 16 Officer.</footnote>
        <footnote id="F3">Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2024-2026 with vesting on January 3, 2027 . The number of shares issued will range from 0% to 200% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2024-2026 , relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.</footnote>
        <footnote id="F4">Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 3, 2027. The number of shares issued will range from 0% to 200% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 3, 2027, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Robert Maynes for Jakob Wedel Christensen</signatureName>
        <signatureDate>2024-04-24</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>doc1.txt
<DESCRIPTION>POWER OF ATTORNEY (PUBLIC): POWER OF ATTORNEY
<TEXT>
POWER OF ATTORNEY
KNOW ALL MEN BY THESE PRESENTS, that the undersigned hereby
constitutes and appoints Scott Davies and Robert Maynes,
and each of them, his or her true and
lawful attorney-in-fact to:
(1)	execute for and on behalf of the undersigned,
in the undersigneds capacity as an officer and/or director
of Illumina, Inc. (the Company), any and all Form 3, 4 and 5
reports required to be filed by the undersigned in accordance
with Section 16(a) of the Securities Exchange Act of 1934
and the rules thereunder;
(2)	do and perform any and all acts for and on behalf
of the undersigned which may be necessary or desirable to
complete and execute any such Form 3, 4 or 5 report and timely
file such report with the United States Securities and Exchange
Commission and any stock exchange or similar authority; and
(3)	take any other action of any type whatsoever in
connection with the foregoing which, in the opinion of such
attorney in-fact, may be of benefit to, in the best interest of,
or legally required by, the undersigned, it being understood
that the documents executed by such attorney in-fact on behalf
of the undersigned, pursuant to this Power of Attorney, shall be
in such form and shall contain such terms and conditions as such
attorney in-fact may approve in his discretion.
The undersigned hereby grants to each such attorney-in-fact
full power and authority to do and perform each and every act
and thing whatsoever requisite, necessary, and proper to be
done in the exercise of any of the rights and powers herein
granted, as fully to all intents and purposes as the undersigned
might or could do if personally present, with full power of
substitution or revocation, hereby ratifying and confirming
all that such attorney-in-fact, or his or her substitute or
substitutes, shall lawfully do or cause to be done by virtue of
this Power of Attorney and the rights and powers herein granted.
The undersigned acknowledges that no such attorney in-fact,
in serving in such capacity at the request of the undersigned,
is hereby assuming, nor is the Company hereby assuming, any of
the undersigneds responsibilities to comply with Section 16
of the Securities Exchange Act of 1934.
This Power of Attorney shall remain in full force and effect
until the undersigned is no longer required to file Form 3, 4
and 5 reports with respect to the undersigneds holdings of and
transactions in securities issued by the Company, unless earlier
revoked by the undersigned in a signed writing delivered to the
foregoing attorneys in-fact.

IN WITNESS WHEREOF, the undersigned has caused this
Power of Attorney to be executed as of this 15th day of
April, 2024.


/s/Jakob Wedel
[Signature]
Jakob Wedel
[Name]

</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
