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SEGMENT AND GEOGRAPHIC INFORMATION
 12 Months Ended
Dec. 29, 2024
Segment Reporting [Abstract]  
SEGMENT AND GEOGRAPHIC INFORMATION
12. SEGMENT AND GEOGRAPHIC INFORMATION
Reportable Segment Information
As of December 29, 2024, we have one reportable segment, Core Illumina. Prior to the Spin-Off of GRAIL, on June 24, 2024, our reportable segments included both Core Illumina and GRAIL. See note 2. GRAIL Spin-Off for details. We continue to disclose certain historical information for GRAIL prior to the Spin-Off. Segment information is consistent with how our Chief Operating Decision Maker (CODM), who is our Chief Executive Officer, reviews financial information, makes operating decisions, allocates resources, and assesses performance. We also consider the way budgets and forecasts are prepared and reviewed and the basis on which executive compensation is determined.
Core Illumina: Core Illumina’s products and services serve customers in the research, clinical and applied markets, and enable the adoption of a variety of genomic solutions. Core Illumina sells products and provides services to GRAIL, and vice versa, in accordance with contractual agreements between the entities.
GRAIL: GRAIL is a healthcare company focused on early detection of multiple cancers. Prior to the Spin-Off of GRAIL into a separate, independent public company, GRAIL was required to be held and operated separately and independently from Illumina pursuant to the transitional measures ordered by the European Commission.
Our CODM allocates resources and evaluates business performance based on revenues and net income (loss). Net income (loss) is used in the annual budgeting and monthly forecasting processes and to monitor and assess budgeted/forecasted versus actual results. Our CODM does not evaluate segments using asset information. The accounting policies for segments are the same as those described in the summary of significant accounting policies.
The following tables present selected financial information with respect to segments for the periods presented:
In millions202420232022
Core Illumina:
Revenue(1)
$4,332 $4,438 $4,553 
Less:
Cost of revenue1,424 1,582 1,446 
Research and development988 1,030 1,004 
Selling and marketing638 648 677 
General and administrative262 600 326 
Goodwill and intangible impairment
3 6 — 
Legal contingency and settlement
(456)20 619 
Core Illumina income from operations1,473 552 481 
GRAIL:
Revenue
55 93 55 
Total operating expenses(2)
2,360 1,714 4,712 
Consolidated other expense, net
346 48 157 
Consolidated provision for income taxes
44 44 68 
Intersegment eliminations
(1)— (3)
Consolidated net loss$(1,223)$(1,161)$(4,404)
_____________
(1)Core Illumina revenue for 2024, 2023, and 2022 included intercompany revenue of $15 million, $26 million, and $24 million, respectively.
(2)GRAIL operating expenses are inclusive of cost of revenue, research and development, selling and marketing, general and administrative, and goodwill and intangible impairment for the comparative periods prior to the Spin-Off on June 24, 2024.
 In millions202420232022
Depreciation and amortization:
Core Illumina$280 $273 $240 
GRAIL74 159 154 
Consolidated depreciation and amortization$354 $432 $394 
Capital expenditures:
Core Illumina$137 $183 $262 
GRAIL5 13 24 
Eliminations— (1)— 
Consolidated capital expenditures$142 $195 $286 
Geographic Data
Long-lived assets, consisting of property and equipment and operating lease right-of-use assets, were as follows:
In millionsDecember 29,
2024		December 31,
2023
United States$750 $1,040 
Singapore279 298 
United Kingdom124 136 
Other countries81 77 
Total long-lived assets, net
$1,234 $1,551 
Refer to note 3. Revenue for revenue by geographic area.