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REVENUE - Disaggregation of Revenue (Details) - USD ($)
$ in Millions
 3 Months Ended
Mar. 30, 2025
Mar. 31, 2024
Disaggregation of Revenue [Line Items]    
Total revenue $ 1,041 $ 1,076
Americas    
Disaggregation of Revenue [Line Items]    
Total revenue 570 603
Europe    
Disaggregation of Revenue [Line Items]    
Total revenue 293 279
Greater China    
Disaggregation of Revenue [Line Items]    
Total revenue 72 78
Asia-Pacific, Middle East, and Africa    
Disaggregation of Revenue [Line Items]    
Total revenue 106 116
Total product revenue    
Disaggregation of Revenue [Line Items]    
Total revenue 880 876
Consumables    
Disaggregation of Revenue [Line Items]    
Total revenue 768 762
Instruments    
Disaggregation of Revenue [Line Items]    
Total revenue 112 114
Service and other revenue    
Disaggregation of Revenue [Line Items]    
Total revenue 161 200
Sequencing    
Disaggregation of Revenue [Line Items]    
Total revenue 947 979
Sequencing | Total product revenue    
Disaggregation of Revenue [Line Items]    
Total revenue 805 801
Sequencing | Consumables    
Disaggregation of Revenue [Line Items]    
Total revenue 696 691
Sequencing | Instruments    
Disaggregation of Revenue [Line Items]    
Total revenue 109 110
Sequencing | Service and other revenue    
Disaggregation of Revenue [Line Items]    
Total revenue 142 178
Microarray    
Disaggregation of Revenue [Line Items]    
Total revenue 94 97
Microarray | Total product revenue    
Disaggregation of Revenue [Line Items]    
Total revenue 75 75
Microarray | Consumables    
Disaggregation of Revenue [Line Items]    
Total revenue 72 71
Microarray | Instruments    
Disaggregation of Revenue [Line Items]    
Total revenue 3 4
Microarray | Service and other revenue    
Disaggregation of Revenue [Line Items]    
Total revenue $ 19 $ 22