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SEGMENT INFORMATION (Tables) | 9 Months Ended
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Sep. 28, 2025
Segment Reporting [Abstract] |
Schedule of Operating Performance and Assets by Segment | The following tables present selected financial information with respect to segments for the periods presented:
In millions | Q3 2025 |  | Q3 2024 |  | YTD 2025 |  | YTD 2024
Core Illumina: |  |  |  |  |  |  |
Revenue (1) | $ | 1,084 |  |  | $ | 1,080 |  |  | $ | 3,184 |  |  | $ | 3,228 |
Less: |  |  |  |  |  |  |
Cost of revenue | 351 |  |  | 335 |  |  | 1,073 |  |  | 1,048 |
Research and development | 229 |  |  | 253 |  |  | 728 |  |  | 732 |
Selling and marketing | 148 |  |  | 163 |  |  | 458 |  |  | 480 |
General and administrative | 129 |  |  | 76 |  |  | 319 |  |  | 141 |
Goodwill and intangible impairment | — |  |  | — |  |  | — |  |  | 3 |
Legal contingency and settlement | — |  |  | (488) |  |  | — |  |  | (474) |
Core Illumina income from operations | 227 |  |  | 741 |  |  | 606 |  |  | 1,298 |
GRAIL: |  |  |  |  |  |  |
Revenue | — |  |  | — |  |  | — |  |  | 55 |
Total operating expenses (2) | — |  |  | — |  |  | — |  |  | 2,360 |
Consolidated other (expense) income, net | (7) |  |  | (21) |  |  | 103 |  |  | (358) |
Consolidated provision for income taxes | 70 |  |  | 15 |  |  | 193 |  |  | 44 |
Intersegment eliminations | — |  |  | — |  |  | — |  |  | (1) |
Consolidated net income (loss) | $ | 150 |  |  | $ | 705 |  |  | $ | 516 |  |  | $ | (1,410) |
_____________ (1)Core Illumina revenue included intercompany revenue of $15 million in YTD 2024. (2)GRAIL operating expenses are inclusive of cost of revenue, research and development, selling and marketing, general and administrative, and goodwill and intangible impairment for the comparative period prior to the Spin-Off on June 24, 2024.
In millions | Q3 2025 |  | Q3 2024 |  | YTD 2025 |  | YTD 2024
Depreciation and amortization: |  |  |  |  |  |  |
Core Illumina | $ | 67 |  |  | $ | 70 |  |  | $ | 204 |  |  | $ | 207 |
GRAIL | — |  |  | — |  |  | — |  |  | 76 |
Consolidated depreciation and amortization | $ | 67 |  |  | $ | 70 |  |  | $ | 204 |  |  | $ | 283 |

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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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