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SEGMENT INFORMATION | 9 Months Ended
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Sep. 28, 2025
Segment Reporting [Abstract] |
SEGMENT INFORMATION |
10. SEGMENT INFORMATION
As of September 28, 2025, we have one reportable segment, Core Illumina. Prior to the Spin-Off of GRAIL, on June 24, 2024, our reportable segments included both Core Illumina and GRAIL. We continue to disclose certain historical information for GRAIL prior to the Spin-Off. Segment information is consistent with how our Chief Operating Decision Maker (CODM), who is our Chief Executive Officer, reviews financial information, makes operating decisions, allocates resources, and assesses performance. We also consider the way budgets and forecasts are prepared and reviewed and the basis on which executive compensation is determined. Core Illumina: Core Illumina’s products and services serve customers in the research, clinical and applied markets, and enable the adoption of a variety of genomic solutions. Core Illumina sells products and provides services to GRAIL, and vice versa, in accordance with contractual agreements between the entities. GRAIL: GRAIL is a healthcare company focused on early detection of multiple cancers. Prior to the Spin-Off of GRAIL into a separate, independent public company, GRAIL was required to be held and operated separately and independently from Illumina pursuant to the transitional measures ordered by the European Commission. Our CODM allocates resources and evaluates business performance based on revenues and net income (loss). Net income (loss) is used in the annual budgeting and monthly forecasting processes and to monitor and assess budgeted/forecasted versus actual results. Our CODM does not evaluate segments using asset information. The following tables present selected financial information with respect to segments for the periods presented:
In millions | Q3 2025 |  | Q3 2024 |  | YTD 2025 |  | YTD 2024
Core Illumina: |  |  |  |  |  |  |
Revenue (1) | $ | 1,084 |  |  | $ | 1,080 |  |  | $ | 3,184 |  |  | $ | 3,228 |
Less: |  |  |  |  |  |  |
Cost of revenue | 351 |  |  | 335 |  |  | 1,073 |  |  | 1,048 |
Research and development | 229 |  |  | 253 |  |  | 728 |  |  | 732 |
Selling and marketing | 148 |  |  | 163 |  |  | 458 |  |  | 480 |
General and administrative | 129 |  |  | 76 |  |  | 319 |  |  | 141 |
Goodwill and intangible impairment | — |  |  | — |  |  | — |  |  | 3 |
Legal contingency and settlement | — |  |  | (488) |  |  | — |  |  | (474) |
Core Illumina income from operations | 227 |  |  | 741 |  |  | 606 |  |  | 1,298 |
GRAIL: |  |  |  |  |  |  |
Revenue | — |  |  | — |  |  | — |  |  | 55 |
Total operating expenses (2) | — |  |  | — |  |  | — |  |  | 2,360 |
Consolidated other (expense) income, net | (7) |  |  | (21) |  |  | 103 |  |  | (358) |
Consolidated provision for income taxes | 70 |  |  | 15 |  |  | 193 |  |  | 44 |
Intersegment eliminations | — |  |  | — |  |  | — |  |  | (1) |
Consolidated net income (loss) | $ | 150 |  |  | $ | 705 |  |  | $ | 516 |  |  | $ | (1,410) |
_____________ (1)Core Illumina revenue included intercompany revenue of $15 million in YTD 2024. (2)GRAIL operating expenses are inclusive of cost of revenue, research and development, selling and marketing, general and administrative, and goodwill and intangible impairment for the comparative period prior to the Spin-Off on June 24, 2024.
In millions | Q3 2025 |  | Q3 2024 |  | YTD 2025 |  | YTD 2024
Depreciation and amortization: |  |  |  |  |  |  |
Core Illumina | $ | 67 |  |  | $ | 70 |  |  | $ | 204 |  |  | $ | 207 |
GRAIL | — |  |  | — |  |  | — |  |  | 76 |
Consolidated depreciation and amortization | $ | 67 |  |  | $ | 70 |  |  | $ | 204 |  |  | $ | 283 |

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 21 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-21 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name 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