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SEGMENT INFORMATION (Tables)

9 Months Ended

Sep. 28, 2025

Segment Reporting [Abstract]

Schedule of Operating Performance and Assets by Segment

The following tables present selected financial information with respect to segments for the periods presented:

In millions			Q3 2025						Q3 2024						YTD 2025						YTD 2024
Core Illumina:
Revenue (1)			$	1,084					$	1,080					$	3,184					$	3,228
Less:
Cost of revenue			351						335						1,073						1,048
Research and development			229						253						728						732
Selling and marketing			148						163						458						480
General and administrative			129						76						319						141
Goodwill and intangible impairment			—						—						—						3
Legal contingency and settlement			—						(488)						—						(474)
Core Illumina income from operations			227						741						606						1,298
GRAIL:
Revenue			—						—						—						55
Total operating expenses (2)			—						—						—						2,360
Consolidated other (expense) income, net			(7)						(21)						103						(358)
Consolidated provision for income taxes			70						15						193						44
Intersegment eliminations			—						—						—						(1)
Consolidated net income (loss)			$	150					$	705					$	516					$	(1,410)

_____________

(1)Core Illumina revenue included intercompany revenue of $15 million in YTD 2024.

(2)GRAIL operating expenses are inclusive of cost of revenue, research and development, selling and marketing, general and administrative, and goodwill and intangible impairment for the comparative period prior to the Spin-Off on June 24, 2024.

In millions			Q3 2025						Q3 2024						YTD 2025						YTD 2024
Depreciation and amortization:
Core Illumina			$	67					$	70					$	204					$	207
GRAIL			—						—						—						76
Consolidated depreciation and amortization			$	67					$	70					$	204					$	283

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- Definition

Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 25
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-25

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 22
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-22

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 30
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-30

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- References

No definition available.

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