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REVENUE - Disaggregation of Revenue (Details) - USD ($)
$ in Millions
 3 Months Ended 9 Months Ended
Sep. 28, 2025
Sep. 29, 2024
Sep. 28, 2025
Sep. 29, 2024
Disaggregation of Revenue [Line Items]        
Total revenue $ 1,084 $ 1,080 $ 3,184 $ 3,268
Americas        
Disaggregation of Revenue [Line Items]        
Total revenue 612 609 1,768 1,852
Europe        
Disaggregation of Revenue [Line Items]        
Total revenue 309 291 911 859
Greater China        
Disaggregation of Revenue [Line Items]        
Total revenue 52 75 187 228
Asia-Pacific, Middle East, and Africa        
Disaggregation of Revenue [Line Items]        
Total revenue 111 105 318 329
Total product revenue        
Disaggregation of Revenue [Line Items]        
Total revenue 927 914 2,719 2,718
Consumables        
Disaggregation of Revenue [Line Items]        
Total revenue 816 807 2,395 2,376
Instruments        
Disaggregation of Revenue [Line Items]        
Total revenue 111 107 324 342
Service and other revenue        
Disaggregation of Revenue [Line Items]        
Total revenue 157 166 465 550
Sequencing        
Disaggregation of Revenue [Line Items]        
Total revenue 1,001 995 2,919 2,989
Sequencing | Total product revenue        
Disaggregation of Revenue [Line Items]        
Total revenue 854 845 2,494 2,490
Sequencing | Consumables        
Disaggregation of Revenue [Line Items]        
Total revenue 747 741 2,183 2,160
Sequencing | Instruments        
Disaggregation of Revenue [Line Items]        
Total revenue 107 104 311 330
Sequencing | Service and other revenue        
Disaggregation of Revenue [Line Items]        
Total revenue 147 150 425 499
Microarray        
Disaggregation of Revenue [Line Items]        
Total revenue 83 85 265 279
Microarray | Total product revenue        
Disaggregation of Revenue [Line Items]        
Total revenue 73 69 225 228
Microarray | Consumables        
Disaggregation of Revenue [Line Items]        
Total revenue 69 66 212 216
Microarray | Instruments        
Disaggregation of Revenue [Line Items]        
Total revenue 4 3 13 12
Microarray | Service and other revenue        
Disaggregation of Revenue [Line Items]        
Total revenue $ 10 $ 16 $ 40 $ 51