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Entity Wide Disclosures (Tables)

3 Months Ended

Mar. 31, 2026

Entity Wide Disclosures [Abstract]

Summary of Revenue by Major Source

The following table disaggregates the Company’s revenue by major source (in thousands):

						Three Months Ended March 31,
						2026						2025
Therapeutic Area
Metabolic						$	237,558					$	148,015
Oncology						201,239						170,476
Other						93,318						95,836
Central Nervous System						80,207						54,901
Cardiology						56,261						58,279
AVAI						38,021						31,063
Total revenue						$	706,604					$	558,570

Schedule of Segment Reporting Information, by Segment

Information about the one reportable segment, significant segment expenses and a reconciliation to condensed consolidated net income is as follows (in thousands):

						Three Months Ended March 31,
						2026						2025
Revenue, net						$	706,604					$	558,570
Operating expenses:
Direct service costs, excluding depreciation and amortization - Employee compensation						164,603						143,927
Direct service costs, excluding depreciation and amortization - Other segment items (a)						33,671						33,889
Reimbursed out-of-pocket expenses						312,004						202,404
Total direct costs						510,278						380,220
Selling, general and administrative						47,917						57,897
Depreciation						6,751						6,694
Amortization						155						236
Total operating expenses						565,101						445,047
Income from operations						141,503						113,523
Other income, net:
Miscellaneous income (expense), net						971						(1,816)
Interest income, net						5,117						6,463
Total other income, net						6,088						4,647
Income before income taxes						147,591						118,170
Income tax provision						23,721						3,575
Segment net income						$	123,870					$	114,595
Reconciliation of profit or loss
Adjustments and reconciling items						—						—
Condensed consolidated net income						$	123,870					$	114,595

(a) Direct service costs, excluding depreciation and amortization - Other segment items includes costs related to inventory, leases, project subcontractors and other direct service costs.

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- Definition

Entity wide disclosures.

+ References

No definition available.

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X

- Definition

Tabular disclosure of disaggregation of revenue into categories depicting how nature, amount, timing, and uncertainty of revenue and cash flows are affected by economic factor.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 5
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-5

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- Definition

Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 25
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-25

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 22
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-22

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 30
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-30

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